Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Innocent Safeukui"'
Autor:
Maisha Khair Nima, Angana Mukherjee, Saiful Arefeen Sazed, Muhammad Riadul Haque Hossainey, Ching Swe Phru, Fatema Tuj Johora, Innocent Safeukui, Anjan Saha, Afsana Alamgir Khan, Aung Swi Prue Marma, Russell E. Ware, Narla Mohandas, Barbara Calhoun, Rashidul Haque, Wasif Ali Khan, Mohammad Shafiul Alam, Kasturi Haldar
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Emerging resistance to artemisinin drugs threatens the elimination of malaria. Resistance is widespread in South East Asia (SEA) and Myanmar. Neighboring Bangladesh, where 90% of infections occur in the Chittagong Hill Tracts (CHTs), lacks r
Externí odkaz:
https://doaj.org/article/793f8d0f3d01417f81e2313a98837877
Autor:
Steven Kho, Labibah Qotrunnada, Leo Leonardo, Benediktus Andries, Putu A I Wardani, Aurelie Fricot, Benoit Henry, David Hardy, Nur I Margyaningsih, Dwi Apriyanti, Agatha M Puspitasari, Pak Prayoga, Leily Trianty, Enny Kenangalem, Fabrice Chretien, Valentine Brousse, Innocent Safeukui, Hernando A Del Portillo, Carmen Fernandez-Becerra, Elamaran Meibalan, Matthias Marti, Ric N Price, Tonia Woodberry, Papa A Ndour, Bruce M Russell, Tsin W Yeo, Gabriela Minigo, Rintis Noviyanti, Jeanne R Poespoprodjo, Nurjati C Siregar, Pierre A Buffet, Nicholas M Anstey
Publikováno v:
PLoS Medicine, Vol 18, Iss 5, p e1003632 (2021)
BackgroundA very large biomass of intact asexual-stage malaria parasites accumulates in the spleen of asymptomatic human individuals infected with Plasmodium vivax. The mechanisms underlying this intense tropism are not clear. We hypothesised that im
Externí odkaz:
https://doaj.org/article/74546525e52f41f58b7455b25283b43b
Autor:
Innocent Safeukui, Noé D. Gomez, Aanuoluwa A. Adelani, Florence Burte, Nathaniel K. Afolabi, Rama Akondy, Peter Velazquez, Anthony Holder, Rita Tewari, Pierre Buffet, Biobele J. Brown, Wuraola A. Shokunbi, David Olaleye, Olugbemiro Sodeinde, James Kazura, Rafi Ahmed, Narla Mohandas, Delmiro Fernandez-Reyes, Kasturi Haldar
Publikováno v:
mBio, Vol 6, Iss 1 (2015)
ABSTRACT Severe malarial anemia (SMA) in semi-immune individuals eliminates both infected and uninfected erythrocytes and is a frequent fatal complication. It is proportional not to circulating parasitemia but total parasite mass (sequestered) in the
Externí odkaz:
https://doaj.org/article/b18bccfedc1f46e3a03ecd402fa15bf1
Autor:
Innocent Safeukui, Pierre A Buffet, Sylvie Perrot, Alain Sauvanet, Beatrice Aussilhou, Safi Dokmak, Anne Couvelard, Dominique Cazals Hatem, Narla Mohandas, Peter H David, Odile Mercereau-Puijalon, Geneviève Milon
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60150 (2013)
Ex vivo perfusion of human spleens revealed innate retention of numerous cultured Plasmodium falciparum ring-infected red blood cells (ring-iRBCs). Ring-iRBC retention was confirmed by a microsphiltration device, a microbead-based technology that mim
Externí odkaz:
https://doaj.org/article/43ecbbd0c7a54427967f7bd367152ea8
Autor:
Md Suhail Alam, Michelle Getz, Innocent Safeukui, Sue Yi, Pamela Tamez, Jenny Shin, Peter Velázquez, Kasturi Haldar
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48273 (2012)
Niemann-Pick Type C (NPC) disease is a rare, genetic, lysosomal disorder with progressive neurodegeneration. Poor understanding of the pathophysiology and a lack of blood-based diagnostic markers are major hurdles in the treatment and management of N
Externí odkaz:
https://doaj.org/article/cef32eab972c4cabbae4138e4920f438
Autor:
Noé D Gómez, Innocent Safeukui, Aanuoluwa A Adelani, Rita Tewari, Janardan K Reddy, Sam Rao, Anthony Holder, Pierre Buffet, Narla Mohandas, Kasturi Haldar
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25477 (2011)
Malaria parasites induce complex cellular and clinical phenotypes, including anemia, cerebral malaria and death in a wide range of mammalian hosts. Host genes and parasite 'toxins' have been implicated in malarial disease, but the contribution of par
Externí odkaz:
https://doaj.org/article/0e1168ea41e646cf824bdca963bfb53e
Publikováno v:
Blood Advances.
Effective treatments for genetic disorders that co-evolved with pathogens require simultaneous betterment of both conditions. Hydroxyurea (HU) offers safe and efficacious treatment for sickle cell anaemia (SCA) by reducing clinical complications, tra
Simultaneous adjunctive treatment of malaria and its co-evolved genetic disorder sickle cell anaemia
Effective treatments for genetic disorders that co-evolved with pathogens require simultaneous betterment of both conditions. Hydroxyurea (HU) offers safe and efficacious treatment for sickle cell anemia (SCA) by reducing clinical complications, tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64a9ca09c0abef75a78be626943f2aea
https://doi.org/10.1101/2022.09.01.506230
https://doi.org/10.1101/2022.09.01.506230
Autor:
Rashidul Haque, Mukherjee A, Wasif A. Khan, Prue Marma As, Mohammad Shafiul Alam, Ching Swe Phru, Hossainey Mrh, Innocent Safeukui, Russell E. Ware, Kasturi Haldar, Barbara Calhoun, Fatema Tuj Johora, Sazed Sa, Saha A, Narla M, Khan Aa, Maisha Khair Nima
The emergence of resistance to artemisinin drugs threatens global malaria control. Resistance is widely seen in South East Asia (SEA) and Myanmar, but not comprehensively assessed in Bangladesh. This is due to lack of measuring parasite clearance tim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d674deb908feda634b6aa60242b2f9a
https://doi.org/10.1101/2021.06.24.21259123
https://doi.org/10.1101/2021.06.24.21259123
Autor:
Nur I. Margyaningsih, Nicholas M. Anstey, Bruce Russell, Innocent Safeukui, Benediktus Andries, Pak Prayoga, Fabrice Chrétien, Leo Leonardo, Matthias Marti, Carmen Fernandez-Becerra, Tonia Woodberry, David Hardy, Labibah Qotrunnada, Ric N. Price, Dwi Apriyanti, Steven Kho, Nurjati Chairani Siregar, Benoit Henry, Papa Alioune Ndour, Gabriela Minigo, Leily Trianty, Tsin W. Yeo, Pierre Buffet, Hernando A. del Portillo, Aurélie Fricot, Agatha M. Puspitasari, Enny Kenangalem, Rintis Noviyanti, Elamaran Meibalan, Jeanne Rini Poespoprodjo, Putu A. I. Wardani
Publikováno v:
New England Journal of Medicine
New England Journal of Medicine, Massachusetts Medical Society, 2021, 384 (21), pp.2067-2069. ⟨10.1056/NEJMc2023884⟩
New England Journal of Medicine, 2021, 384 (21), pp.2067-2069. ⟨10.1056/NEJMc2023884⟩
New England Journal of Medicine, Massachusetts Medical Society, 2021, 384 (21), pp.2067-2069. ⟨10.1056/NEJMc2023884⟩
New England Journal of Medicine, 2021, 384 (21), pp.2067-2069. ⟨10.1056/NEJMc2023884⟩
Malaria and the Spleen In this report, patients living in a malaria-endemic area underwent trauma-related splenectomy. In these asymptomatic patients who were naturally infected with Plasmodium fal...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a0cab37fecec78cafd4c72bfcc3837b
https://hal-pasteur.archives-ouvertes.fr/pasteur-03249650/file/nejmc2023884.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-03249650/file/nejmc2023884.pdf