Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Inner acrosomal membrane"'
Autor:
Michaela Bartóková, Jana Antalíková, Jana Jankovičová, Kateřina Komrsková, Petra Sečová, Eliska Valaskova, Michaela Frolikova, L'. Horovská, Pavla Manaskova-Postlerova, V. Palenikova, Jiri Cerny
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
The physiological importance of CD151 tetraspanin is known from somatic cells and its outside-in signalling through integrins was described. In male germ cells, two tetraspanins, CD9 and CD81, are involved in sperm-egg membrane fusion, and similarly
Autor:
Katerina Komrskova, Pavla Postlerova, Veronika Palenikova, Eliska Valaskova, Michaela Frolikova
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9525, p 9525 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 17
International Journal of Molecular Sciences
Volume 22
Issue 17
Integrins are transmembrane receptors that facilitate cell adhesion and cell–extracellular matrix communication. They are involved in the sperm maturation including capacitation and gamete interaction, resulting in successful fertilization. αV int
Publikováno v:
Molecular reproduction and developmentREFERENCES. 88(7)
Many factors are involved in acrosome biogenesis in order for appropriate acrosome formation to occur. Here, we demonstrate that IZUMO family member 3, IZUMO3, plays an important role in acrosome biogenesis, as proven by gene disruption experiments.
Publikováno v:
Gene. 773
Vitamin E is generally believed to promote the production of ovine sperm mainly through its antioxidant effect. Our previous studies have shown that some non-antioxidant genes may also be key in mediating this process. The objective of this study was
Publikováno v:
Molecular reproduction and developmentREFERENCES.
We isolated the transmembrane and coiled-coil domains 2 (Tmco2) gene using a polymerase chain reaction-based subtraction technique. Tmco2 is predominantly expressed in rat testes starting from 4 weeks of age. Rat TMCO2 consists of 187 amino acids wit
Autor:
Erma Z. Drobnis, Wei Xu, Miriam Sutovsky, Richard Oko, Nicolai V. Bovin, Karl Kerns, Mark R. Ellersieck, Momal Sharif, Lauren E. Hamilton, Peter Sutovsky, Michal Zigo, David J. Miller
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2121 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 6
International Journal of Molecular Sciences
Volume 21
Issue 6
Building on our recent discovery of the zinc signature phenomenon present in boar, bull, and human spermatozoa, we have further characterized the role of zinc ions in the spermatozoa&rsquo
s pathway to fertilization. In boar, the zinc signature
s pathway to fertilization. In boar, the zinc signature
Autor:
Fenghua Lu, Shun Zhang, Peng Huo, Qingyou Liu, Xiaomei Guan, Xiaocan Lei, Deshun Shi, Jianrong Jiang
Publikováno v:
Molecular Biology Reports. 46:251-259
The binding of exogenous DNA to sperm is a key process for sperm-mediated gene transfer; however, the underlying molecular mechanisms have yet to be elucidated. In the present study, we aimed to identify the DNA binding proteins (DBPs) in rabbit sper
Autor:
M. Kathryn Liszewski, John P. Atkinson
Publikováno v:
The Complement FactsBook ISBN: 9780127333601
Publisher Summary This chapter provides an overview of Membrane Cofactor Protein (MCP), which is a type 1 membrane glycoprotein expressed as four common isoforms (C1, C2, BC1, and BC2) that arise by alternative splicing. MCP is a cofactor for the fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e989d6ff3628817657a4424036ce480
https://doi.org/10.1016/b978-0-12-810420-0.00026-2
https://doi.org/10.1016/b978-0-12-810420-0.00026-2
Publikováno v:
Journal of Biological Chemistry. 290:17710-17723
Oviductosomes ((OVS), exosomes/microvesicles), which deliver the Ca2+ efflux pump, plasma membrane Ca2+ATPase 4 (PMCA4), to sperm are likely to play an important role in sperm fertilizing ability (Al-Dossary, A. A., Strehler, E. E., and Martin-DeLeon
Autor:
Thomas Karaouzène, Julie Delaroche, Jessica Escoffier, Christophe Arnoult, Pierre F. Ray, Sylviane Hennebicq, Raoudha Zouari, Rafael A. Fissore, Karin Pernet-Gallay, Sandra Yassine, Guillaume Martinez, Charles Coutton, Catherine Metzler-Guillemain, Hoi Chang Lee
Publikováno v:
MHR: Basic science of reproductive medicine. 21:157-168
We recently identified the DPY19L2 gene as the main genetic cause of human globozoospermia (70%) and described that Dpy19l2 knockout (KO) mice faithfully reproduce the human phenotype of globozoospermia making it an excellent model to characterize th