Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Innate/*genetics"'
Publikováno v:
Viruses, vol. 14, no. 8, pp. 1666
Epitranscriptomics, i.e., chemical modifications of RNA molecules, has proven to be a new layer of modulation and regulation of protein expression, asking for the revisiting of some aspects of cellular biology. At the virological level, epitranscript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1900::5acd9e619a399ed891ea3b248868f9af
https://serval.unil.ch/notice/serval:BIB_169EFDDEF7AA
https://serval.unil.ch/notice/serval:BIB_169EFDDEF7AA
Autor:
W. A. Bemelman, Jochem H. Bernink, Lisette Krabbendam, Christianne J. Buskens, Chantal M. A. Kradolfer, Nienke J. E. Haverkate, Hergen Spits, M Becker, Balthasar A. Heesters
Publikováno v:
Nature communications, 12(1):5841. Nature Publishing Group
Nature Communications, 12(1):5841. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature Communications, 12(1), 1. Nature Publishing Group
Nature Communications, 12(1):5841. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature Communications, 12(1), 1. Nature Publishing Group
Phenotypic definition of helper ILC1 and NK cells is problematic due to overlapping markers. Recently we showed the identification of cytotoxic ILC3s characterized by expression of CD94. Here we analyse CD127+ ILCs and NK cells in intestinal lamina p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f083059747cc9d7bac97f9593c7a2022
https://pure.amc.nl/en/publications/cd127-cd94-innate-lymphoid-cells-expressing-granulysin-and-perforin-are-expanded-in-patients-with-crohns-disease(b96c4eec-38f0-428b-992c-5963bbe26c6d).html
https://pure.amc.nl/en/publications/cd127-cd94-innate-lymphoid-cells-expressing-granulysin-and-perforin-are-expanded-in-patients-with-crohns-disease(b96c4eec-38f0-428b-992c-5963bbe26c6d).html
Autor:
Vincenzo Lagani, Ioannis Tsamardinos, Ekaterini Chatzaki, Oluf Dimitri Røe, Georgios Papoutsoglou, Naomi Thomson, Makrina Karaglani
Publikováno v:
Scientific Reports
Papoutsoglou, G, Karaglani, M, Lagani, V, Thomson, N, Røe, O D, Tsamardinos, I & Chatzaki, E 2021, ' Automated machine learning optimizes and accelerates predictive modeling from COVID-19 high throughput datasets ', Scientific Reports, vol. 11, no. 1, 15107 . https://doi.org/10.1038/s41598-021-94501-0
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Papoutsoglou, G, Karaglani, M, Lagani, V, Thomson, N, Røe, O D, Tsamardinos, I & Chatzaki, E 2021, ' Automated machine learning optimizes and accelerates predictive modeling from COVID-19 high throughput datasets ', Scientific Reports, vol. 11, no. 1, 15107 . https://doi.org/10.1038/s41598-021-94501-0
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
COVID-19 outbreak brings intense pressure on healthcare systems, with an urgent demand for effective diagnostic, prognostic and therapeutic procedures. Here, we employed Automated Machine Learning (AutoML) to analyze three publicly available high thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02549b9121b7e618e07247c67d2f9d6f
https://hdl.handle.net/11250/3048235
https://hdl.handle.net/11250/3048235
Autor:
Maxime M. Vroegindewey, Rohit M. Oemrawsingh, Isabella Kardys, Folkert W. Asselbergs, Pim van der Harst, Anton J. Oude Ophuis, G. Etienne Cramer, Arthur Maas, S. Hong Kie The, Alexander J. Wardeh, Henk Mouthaan, Eric Boersma, K. Martijn Akkerhuis
Publikováno v:
Biomarkers, 24(2), 199-205. Taylor & Francis Ltd
Biomarkers, 24, 199-205
Biomarkers, 24(2), 199. Informa Healthcare
Biomarkers, 24, 2, pp. 199-205
Biomarkers, 24(2), 199-205. Informa Healthcare
Biomarkers, 24, 199-205
Biomarkers, 24(2), 199. Informa Healthcare
Biomarkers, 24, 2, pp. 199-205
Biomarkers, 24(2), 199-205. Informa Healthcare
Purpose: We assessed the temporal pattern of 29 immune and inflammatory proteins in post-acute coronary syndrome (ACS) patients, prior to the development of recurrent ACS. Methods: High-frequency blood sampling was performed in 844 patients admitted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4627e5c16117cd60b7548d31995dea7d
https://pubmed.ncbi.nlm.nih.gov/30514120
https://pubmed.ncbi.nlm.nih.gov/30514120
Autor:
Norman Adlung, Ulla Bonas
Publikováno v:
Adlung, N & Bonas, U 2017, ' Dissecting virulence function from recognition : cell death suppression in Nicotiana benthamiana by XopQ/HopQ1-family effectors relies on EDS1-dependent immunity ', Plant Journal, vol. 91, no. 3, pp. 430-442 . https://doi.org/10.1111/tpj.13578
Summary Many Gram-negative plant pathogenic bacteria express effector proteins of the XopQ/HopQ1 family which are translocated into plant cells via the type III secretion system during infection. In Nicotiana benthamiana, recognition of XopQ/HopQ1 pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fb065299a2774ddaae83484be5ab60
https://cris.vtt.fi/en/publications/66a5111b-9d5a-4221-b16c-f21e32bf6955
https://cris.vtt.fi/en/publications/66a5111b-9d5a-4221-b16c-f21e32bf6955
Autor:
Christian Krapp, Jens von Einem, Marisa Gariglio, Sara Pautasso, Valentina Dell'Oste, Francesca Gugliesi, Santo Landolfo, Martin R. Jakobsen, Matteo Biolatti, Cinzia Borgogna, Marco De Andrea
Publikováno v:
Biolatti, M, Dell'Oste, V, Pautasso, S, Gugliesi, F, von Einem, J, Krapp, C, Jakobsen, M R, Borgogna, C, Gariglio, M, De Andrea, M & Landolfo, S 2018, ' Human cytomegalovirus tegument protein pp65 (pUL83) dampens type I interferon production by inactivating the DNA sensor cGAS without affecting STING ', Journal of Virology, vol. 92, no. 6, e01774-17 . https://doi.org/10.1128/JVI.01774-17
The innate immune response plays a pivotal role during human cytomegalovirus (HCMV) primary infection. Indeed, HCMV infection of primary fibroblasts rapidly triggers strong induction of type I interferons (IFN-I), accompanied by proinflammatory cytok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72dfe9f54707f7fe560255620c1c97d7
https://pure.au.dk/portal/da/publications/human-cytomegalovirus-tegument-protein-pp65-pul83-dampens-type-i-interferon-production-by-inactivating-the-dna-sensor-cgas-without-affecting-sting(63238203-e4d3-4976-963e-343095a20474).html
https://pure.au.dk/portal/da/publications/human-cytomegalovirus-tegument-protein-pp65-pul83-dampens-type-i-interferon-production-by-inactivating-the-dna-sensor-cgas-without-affecting-sting(63238203-e4d3-4976-963e-343095a20474).html
Autor:
Petar Scepanovic, Julie Hunkapiller, Jacob Bergstedt, Alejandra Urrutia, Jacques Fellay, Lluis Quintana-Murci, Hélène Quach, Friederike Jönsson, Cherie Green, Olivier Lantz, Lars Rogge, Stéphanie Thomas, Vincent Rouilly, Barbara Piasecka, Yoong Wearn Lim, Claire Leloup, Cécile Alanio, Isabelle Peguillet, Christian Hammer, Benoit Beitz, Magnus Fontes, Magge Zepeda, Matthew L. Albert, Valentina Libri, James P. Di Santo, Etienne Patin, Milena Hasan, François Huetz, Darragh Duffy
Publikováno v:
Nature Immunology
Nature Immunology, 2018, 19 (3), pp.302-314. ⟨10.1038/s41590-018-0049-7⟩
Nature Immunology, Nature Publishing Group, 2018, 19 (3), pp.302-314. ⟨10.1038/s41590-018-0049-7⟩
Nature Immunology, 2018, 19 (3), pp.302-314. ⟨10.1038/s41590-018-0049-7⟩
Nature Immunology, Nature Publishing Group, 2018, 19 (3), pp.302-314. ⟨10.1038/s41590-018-0049-7⟩
A Publisher Correction to this article was published on 03 May 2018; International audience; The quantification and characterization of circulating immune cells provide key indicators of human health and disease. To identify the relative effects of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7632e50a0858023a8e68c6aaad539182
https://hal-pasteur.archives-ouvertes.fr/pasteur-01768943
https://hal-pasteur.archives-ouvertes.fr/pasteur-01768943
Autor:
Thierry Calandra, Pierre-Yves Bochud
Publikováno v:
Clinical Infectious Diseases, vol. 49, no. 5, pp. 733-735
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a424ca67edf73e548a300a7e499958a9
http://doc.rero.ch/record/301751/files/49-5-733.pdf
http://doc.rero.ch/record/301751/files/49-5-733.pdf
Autor:
Ansari, M. Azim, Pedergnana, Vincent, Ip, Camilla L.C., Magri, Andrea, Von Delft, Annette, Bonsall, David, Chaturvedi, Nimisha, Bartha, Istvan, Smith, David, Nicholson, George, McVean, Gilean, Trebes, Amy, Piazza, Paolo, Fellay, Jacques, Cooke, Graham, Foster, Graham R., Hudson, Emma, McLauchlan, John, Simmonds, Peter, Bowden, Rory, Klenerman, Paul, Barnes, Eleanor, Spencer, Chris C.A., STOP-HCV Consortium
Publikováno v:
Nature genetics
Nature genetics, vol. 49, no. 5, pp. 666-673
Nature genetics, vol. 49, no. 5, pp. 666-673
Outcomes of hepatitis C virus (HCV) infection and treatment depend on viral and host genetic factors. Here we use human genome-wide genotyping arrays and new whole-genome HCV viral sequencing technologies to perform a systematic genome-to-genome stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd7b4a18157ec361570ab2d4df374b1e
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Autor:
Tobias Sahr, Clement Bertholet, Carmen Buchrieser, Christophe Rusniok, Raphaël Margueron, Serena Sanulli, Monica Rolando, Laura Gomez-Valero
Publikováno v:
Cell Host and Microbe
Cell Host and Microbe, Elsevier, 2013, 13 (4), pp.395-405. ⟨10.1016/j.chom.2013.03.004⟩
Cell Host and Microbe, 2013, 13 (4), pp.395-405. ⟨10.1016/j.chom.2013.03.004⟩
Cell Host and Microbe, Elsevier, 2013, 13 (4), pp.395-405. ⟨10.1016/j.chom.2013.03.004⟩
Cell Host and Microbe, 2013, 13 (4), pp.395-405. ⟨10.1016/j.chom.2013.03.004⟩
International audience; Histone posttranslational modifications control eukaryotic gene expression and regulate many biological processes including immunity. Pathogens alter host epigenetic control to aid pathogenesis. We find that the intracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7f9ba679975f15521adf796cc088f3