Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Inna Sekirov"'
Autor:
Omid Gheysar Gharamaleki, Caroline Colijn, Inna Sekirov, James C. Johnston, Benjamin Sobkowiak
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Identifying individuals with tuberculosis (TB) with a high risk of onward transmission can guide disease prevention and public health strategies. Here, we train classification models to predict the first sampled isolates in Mycobacterium tub
Externí odkaz:
https://doaj.org/article/e302d150f2704ac39643dfc1dfe1fa20
Autor:
Gabrielle N. Gaultier, Brynn McMillan, Chad Poloni, Mandy Lo, Bing Cai, Jean J. Zheng, Hannah M. Baer, Hennady P. Shulha, Karen Simmons, Ana Citlali Márquez, Sofia R. Bartlett, Laura Cook, Megan K. Levings, Theodore Steiner, Inna Sekirov, James E. A. Zlosnik, Muhammad Morshed, Danuta M. Skowronski, Mel Krajden, Agatha N. Jassem, Manish Sadarangani
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract To evaluate immune responses to COVID-19 vaccines in adults aged 50 years and older, spike protein (S)-specific antibody concentration, avidity, and function (via angiotensin-converting enzyme 2 (ACE2) inhibition surrogate neutralization and
Externí odkaz:
https://doaj.org/article/b21ce8f9399a4f10afbf41b7b7c5bfbe
Autor:
Aidan M. Nikiforuk, Kevin S. Kuchinski, Katy Short, Susan Roman, Mike A. Irvine, Natalie Prystajecky, Agatha N. Jassem, David M. Patrick, Inna Sekirov
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Widespread human-to-human transmission of the severe acute respiratory syndrome coronavirus two (SARS-CoV-2) stems from a strong affinity for the cellular receptor angiotensin converting enzyme two (ACE2). We investigate the relat
Externí odkaz:
https://doaj.org/article/176ef97582e64aeea44aa7bf8ecdd203
Autor:
Sarah L. Silverberg, Hennady P. Shulha, Brynn McMillan, Guanyuhui He, Amy Lee, Ana Citlali Márquez, Sofia R. Bartlett, Vivek Gill, Bahaa Abu-Raya, Julie A. Bettinger, Adriana Cabrera, Daniel Coombs, Soren Gantt, David M. Goldfarb, Laura Sauvé, Mel Krajden, Muhammad Morshed, Inna Sekirov, Agatha N. Jassem, Manish Sadarangani
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background and objectives Pediatric COVID-19 cases are often mild or asymptomatic, which has complicated estimations of disease burden using existing testing practices. We aimed to determine the age-specific population seropositivity and ris
Externí odkaz:
https://doaj.org/article/9b9fcfc8760f46279eee464e73b49d21
Autor:
Hudson Reddon, Brittany Barker, Sofia Bartlett, Ana Citlali Márquez, Inna Sekirov, Agatha Jassem, Muhammad Morshed, Ari Clemens, Phoenix Beck McGreevy, Kanna Hayashi, Kora DeBeck, Mel Krajden, M.-J. Milloy, Maria Eugenia Socías
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract We sought to evaluate the rates and predictors of SARS-CoV-2 vaccination among members of a structurally-marginalized population of people who use drugs (PWUD) during a targeted, community-wide, vaccination campaign in Vancouver, Canada. Int
Externí odkaz:
https://doaj.org/article/a9e30041cb2a474cad34d99f9d5c968d
Autor:
Meenu Kaushal Sharma, Michael Stobart, Pierre-Marie Akochy, Heather Adam, Debra Janella, Melissa Rabb, Mohey Alawa, Inna Sekirov, Gregory J. Tyrrell, Hafid Soualhine
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6245 (2024)
Phenotypic susceptibility testing of the Mycobacterium tuberculosis complex (MTBC) isolate requires culture growth, which can delay rapid detection of resistant cases. Whole genome sequencing (WGS) and data analysis pipelines can assist in predicting
Externí odkaz:
https://doaj.org/article/b08359b62af247d586bbef56fadd1c1b
Autor:
James W. Saville, Dhiraj Mannar, Xing Zhu, Shanti S. Srivastava, Alison M. Berezuk, Jean-Philippe Demers, Steven Zhou, Katharine S. Tuttle, Inna Sekirov, Andrew Kim, Wei Li, Dimiter S. Dimitrov, Sriram Subramaniam
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Saville, Mannar et al. provide a structural basis for enhanced antibody evasion and ACE2 binding by the Delta SARS-CoV-2 spike protein. They further identify a head-to-head dimer-of-trimers cryoEM reconstruction unique to the Kappa variant spike.
Externí odkaz:
https://doaj.org/article/feef3d51eb6145eeb9cb3f29799a3060
Autor:
Aidan M. Nikiforuk, Brynn McMillan, Sofia R. Bartlett, Ana Citlali Márquez, Tamara Pidduck, Jesse Kustra, David M. Goldfarb, Vilte Barakauskas, Graham Sinclair, David M. Patrick, Manish Sadarangani, Gina S. Ogilvie, Mel Krajden, Muhammad Morshed, Inna Sekirov, Agatha N. Jassem
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
Externí odkaz:
https://doaj.org/article/043dfd761af8495688053aa2d37278bf
Autor:
Carmen Charlton, Jamil Kanji, Vanessa Tran, Julianne Kus, Jonathan Gubbay, Carla Osiowy, Jason Robinson, Inna Sekirov, Michael Drebot, Todd Hatchette, Derek Stein, Nadia El-Gabalawy, Amanda Lang, Lei Jiao, Paul Levett, Heidi Wood, Christian Therrien, L Robbin Lindsay, Muhammad Morshed, Jessica Forbes, Antonia Dibernardo
Publikováno v:
Canada Communicable Disease Report, Vol 47, Iss 4, Pp 171-183 (2021)
The landscape of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnostic testing is rapidly evolving. While serology testing has limited diagnostic capacity for acute infection, its role in providing population-based information on
Externí odkaz:
https://doaj.org/article/e43ae1b010cc405db886e97ce6d57a3e
Autor:
Aidan M. Nikiforuk, Brynn McMillan, Sofia R. Bartlett, Ana Citlali Márquez, Tamara Pidduck, Jesse Kustra, David M. Goldfarb, Vilte Barakauskas, Graham Sinclair, David M. Patrick, Manish Sadarangani, Gina S. Ogilvie, Mel Krajden, Muhammad Morshed, Inna Sekirov, Agatha N. Jassem
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 2 (2022)
ABSTRACT We investigate the diagnostic accuracy and predictive value of finger prick capillary dried blood spot (DBS) samples tested by a quantitative multiplex anti-immunoglobulin G (IgG) assay to detect severe acute respiratory syndrome coronavirus
Externí odkaz:
https://doaj.org/article/43516333bf4a4eaa9daa77e41d317b7f