Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Inna Saporoschetz"'
Autor:
Inna Saporoschetz, K. Collins, Miriam Nestor, Mary L. Rodrick, John A. Mannick, Paul Curley, M. V. Mendez
Publikováno v:
Gastroenterology. 110:583-588
The role of the cytokine interleukin 2 (IL-2) has long been recognized as central to normal immunologic function and defense against infection after burns and trauma, but little effort has been directed towards its role in acute pancreatitis (AP), wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cf76df7c14af00db34a5ed5b39d4feb
https://doi.org/10.1053/gast.1996.v110.pm8566607
https://doi.org/10.1053/gast.1996.v110.pm8566607
Autor:
Richard G Molloy, M L Rodrick, M. V. Mendez, M. Nestor, John A. Mannick, Inna Saporoschetz, Diarmuid S. O'Riordain, K. Collins, Paul Curley, René G Holzheimer
Publikováno v:
The Journal of Trauma: Injury, Infection, and Critical Care. 38:757-762
Major thermal or traumatic injury often results in abnormalities of immune function, and these abnormalities contribute to the increased susceptibility to infection observed in these patients. Abnormalities of T-cell function, including decreased pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758c4249bcb00e55ef58513f7530f766
https://doi.org/10.1097/00005373-199505000-00014
https://doi.org/10.1097/00005373-199505000-00014
Autor:
Deric D. Schoof, John A. Mannick, M. V. Mendez, M. Nestor, Inna Saporoschetz, Mary L. Rodrick, A. Obando, Richard G Molloy, Diarmuid S. O'Riordain, René G Holzheimer
Publikováno v:
Journal of Surgical Research. 54:565-570
It has previously been shown by this laboratory that immunomodulation of thermally injured animals with low-dose interleukin-1 (IL-2) and indomethacin (Indo) improves survival following septic challenge. Lymphokine-activated killer (LAK) cells have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11233b7f0c57b563c27bbcbb5307bf5
https://doi.org/10.1006/jsre.1993.1086
https://doi.org/10.1006/jsre.1993.1086
Autor:
René G Holzheimer, Jane M. Doherty, Mary L. Rodrick, Inna Saporoschetz, John A. Mannick, Paul Curley
Publikováno v:
Shock (Augusta, Ga.). 17(6)
Although there are many reports of circadian variation in hormone secretion, there are only a few reports on the relationship between circadian rhythm and cytokine production. The aim of the present studies was to investigate whether there is a circa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8741235d8499b3a5f4cdbca637e69d4d
https://pubmed.ncbi.nlm.nih.gov/12069192
https://pubmed.ncbi.nlm.nih.gov/12069192
Autor:
Mary L. Rodrick, Ann Lyons, Andreas Goebel, Inna Saporoschetz, James A. Lederer, John A. Mannick, Christopher C. Soberg, Eamon G. Kavanagh
Publikováno v:
Annals of surgery. 231(2)
Serious injury induces diminished resistance to infection, and sepsis is a leading cause of death in injured patients who survive initial resuscitation. Attempting to explain this phenomenon, numerous investigators over the past two decades have docu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db60dd94540d104c73ae4c4f7b4922d6
https://pubmed.ncbi.nlm.nih.gov/10674618
https://pubmed.ncbi.nlm.nih.gov/10674618
Publikováno v:
Immunology and Its Impact on Infections in Surgery ISBN: 9783540581451
Endotoxin is thought to play a central role in the development of irreversible multi-organ failure in patients with septic shock which is the largest cause of mortality in the intensive care setting [1]. Antiserum to the central core of endotoxin has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::673ecd82efe0eeec493f0dca19cd9e05
https://doi.org/10.1007/978-3-642-79079-9_3
https://doi.org/10.1007/978-3-642-79079-9_3
Autor:
Douglas W. Wilmore, M L Rodrick, Danny O. Jacobs, John A. Mannick, Jan D. Rounds, Inna Saporoschetz, K. Collins, Malcolm K. Robinson
Publikováno v:
Archives of surgery (Chicago, Ill. : 1960). 128(1)
• Critical illness is associated with both immunosuppression and glutathione deficiency. We determined if in vivo depletion of glutathione would adversely affect immune status. Rats with normal glutathione levels and those with glutathione stores d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e535def73715fa6dd1c6383095e68d8
https://pubmed.ncbi.nlm.nih.gov/8418777
https://pubmed.ncbi.nlm.nih.gov/8418777
Autor:
Michael Pilz, M. G. O'riordain, Inna Saporoschetz, John A. Mannick, Mary L. Rodrick, K. Collins
Publikováno v:
Archives of Surgery. 127:152
• Macrophage hyperactivity with increased production of tumor necrosis factor, interleukin 6, interleukin 1, and prostaglandins has been demonstrated in the injured patient, but the effect of this on the clinical outcome is unclear. We studied the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e209ca0a950da49b4c37308f50cd0e5
https://doi.org/10.1001/archsurg.1992.01420020034005
https://doi.org/10.1001/archsurg.1992.01420020034005
Autor:
Gerard A. Mcloughlin, Richard B. Nimberg, Inna Saporoschetz, John A. Mannick, Andrew V. O. Wu
Publikováno v:
Annals of Surgery. 190:297-304
In order to clarify the relationship between anergy and immunosuppressive activity in the serum, we studied 46 previously well patients before and at three, five, seven and 28 days after surgery. Delayed hypersensitivity was measured by skin testing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f12bcd616afb9916328b72837001f0b
https://doi.org/10.1097/00000658-197909000-00004
https://doi.org/10.1097/00000658-197909000-00004
Autor:
Nuala M. Moss, John T. Grbic, Andrea Jordan, John A. Mannick, Mary L. Rodrick, Inna Saporoschetz, J J Wood, Robert H. Demling, Carl Davis, J B O'Mahony, Philip D'Eon
Publikováno v:
Journal of Clinical Immunology. 6:310-318
Depression of cell-mediated immunity in patients following severe traumatic injury has been well documentedin vitro andin vivo. However, the exact mechanism of this defect is still controversial. In this study, we have investigated the ability of inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194722e1c65f11da197361090994ac9e
https://doi.org/10.1007/bf00917332
https://doi.org/10.1007/bf00917332