Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Inna Sabirzhanova"'
Autor:
Qiangni Liu, Inna Sabirzhanova, Emily Anne Smith Bergbower, Murali Yanda, William G. Guggino, Liudmila Cebotaru
Publikováno v:
Cellular Physiology and Biochemistry, Vol 53, Iss 2, Pp 400-412 (2019)
Externí odkaz:
https://doaj.org/article/1d8386bd756c4850bba50f5942e57680
Autor:
Emily Anne Smith Bergbower, Inna Sabirzhanova, Clément Boinot, William B. Guggino, Liudmila Cebotaru
Publikováno v:
Cellular Physiology and Biochemistry, Vol 52, Iss 6, Pp 1267-1279 (2019)
Externí odkaz:
https://doaj.org/article/6ad549979b1249a096b4e70ac778cad6
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 3, Pp 1489-1499 (2018)
Background/Aims: Cystic fibrosis (CF) is a lethal recessive disorder caused by mutations in the CF transmembrane conductance regulator (CFTR). ΔF508, the most common mutation, is a misfolded protein that is retained in the endoplasmic reticulum and
Externí odkaz:
https://doaj.org/article/72a194b27d754f52b3001997eeaefa36
Publikováno v:
Cellular Physiology and Biochemistry, Vol 45, Iss 2, Pp 639-655 (2018)
Background/Aims: The CFTR-Associated Ligand (CAL), a PDZ domain containing protein with two coiled-coil domains, reduces cell surface WT CFTR through degradation in the lysosome by a well-characterized mechanism. However, CAL’s regulatory effect on
Externí odkaz:
https://doaj.org/article/04ac1ab1782b4b678f077cdbabf31b2c
Publikováno v:
Cellular Physiology and Biochemistry, Vol 41, Iss 6, Pp 2194-2210 (2017)
Background/Aims: Premature degradation of mutated cystic fibrosis transmembrane conductance regulator (CFTR) protein causes cystic fibrosis (CF), the commonest Mendelian disease in Caucasians. Despite recent advances in precision medicines for CF pat
Externí odkaz:
https://doaj.org/article/d1bd1adde0284c35a122fc0d9f0b6a7e
Autor:
Daniele Rapino, Inna Sabirzhanova, Miquéias Lopes-Pacheco, Rahul Grover, William B Guggino, Liudmila Cebotaru
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119796 (2015)
Although, the most common Cystic Fibrosis mutation, ΔF508, in the cystic fibrosis transmembrane regulator. (CFTR), is located in nucleotide binding domain (NBD1), disease-causing mutations also occur in NBD2. To provide information on potential ther
Externí odkaz:
https://doaj.org/article/1bdf52ead2e6454183d9cd5473573926
Publikováno v:
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Cellular Physiology and Biochemistry, Vol 51, Iss 3, Pp 1489-1499 (2018)
Cellular Physiology and Biochemistry, Vol 51, Iss 3, Pp 1489-1499 (2018)
Background/Aims: Cystic fibrosis (CF) is a lethal recessive disorder caused by mutations in the CF transmembrane conductance regulator (CFTR). ΔF508, the most common mutation, is a misfolded protein that is retained in the endoplasmic reticulum and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec0aadb18a49f00c9e3c2f0883e1112
http://europepmc.org/articles/PMC6482459
http://europepmc.org/articles/PMC6482459
Autor:
Inna Sabirzhanova, William B. Guggino, Qiangni Liu, Liudmila Cebotaru, Emily Bergbower, Clément Boinot, Murali K. Yanda
Publikováno v:
Journal of Cystic Fibrosis. 17:582-594
The missing phenylalanine at position 508, located in nucleotide-binding domain (NBD1) of the cystic fibrosis transmembrane regulator (CFTR), is the most common cystic fibrosis mutation. Severe disease-causing mutations also occur in NBD2. To provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59efb62285220a94c48be73432b40d55
https://doi.org/10.1016/j.jcf.2018.05.016
https://doi.org/10.1016/j.jcf.2018.05.016
Publikováno v:
Cellular Physiology and Biochemistry, Vol 41, Iss 6, Pp 2194-2210 (2017)
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Background/Aims: Premature degradation of mutated cystic fibrosis transmembrane conductance regulator (CFTR) protein causes cystic fibrosis (CF), the commonest Mendelian disease in Caucasians. Despite recent advances in precision medicines for CF pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9805f3caab76ae25cfc1fea5df0af1c5
https://doi.org/10.1159/000475578
https://doi.org/10.1159/000475578
Autor:
William G Guggino, Murali K. Yanda, Qiangni Liu, Liudmila Cebotaru, Emily Bergbower, Inna Sabirzhanova
Publikováno v:
Cellular Physiology and Biochemistry, Vol 53, Iss 2, Pp 400-412 (2019)
Background/aims Mutations in ABCA4 cause Stargardt macular degeneration, which invariably ends in legal blindness. We studied two common mutants, A1038V (in NBD1) and G1961E (in NBD2), with the purpose of exploring how they interact with the cell's q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b0915325c46ccb7f282b304df909b6
https://pubmed.ncbi.nlm.nih.gov/31403270
https://pubmed.ncbi.nlm.nih.gov/31403270