Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Inna Rozman Grinberg"'
Autor:
Ornella Bimai, Ipsita Banerjee, Inna Rozman Grinberg, Ping Huang, Lucas Hultgren, Simon Ekström, Daniel Lundin, Britt-Marie Sjöberg, Derek T Logan
Publikováno v:
eLife, Vol 12 (2024)
A small, nucleotide-binding domain, the ATP-cone, is found at the N-terminus of most ribonucleotide reductase (RNR) catalytic subunits. By binding adenosine triphosphate (ATP) or deoxyadenosine triphosphate (dATP) it regulates the enzyme activity of
Externí odkaz:
https://doaj.org/article/58c8ed64ca754d1ea6c8072d269703e7
Autor:
Inna Rozman Grinberg, Markel Martínez-Carranza, Ornella Bimai, Ghada Nouaïria, Saher Shahid, Daniel Lundin, Derek T. Logan, Britt-Marie Sjöberg, Pål Stenmark
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Ribonucleotide reductase (RNR) is an essential enzyme that catalyzes the synthesis of DNA building blocks. Here, the authors present the cryo-EM structure and mechanism of action of NrdR, the RNR-specific repressor, that controls transcription of RNR
Externí odkaz:
https://doaj.org/article/c11cf65babe14228a3e8ad1e379ec405
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
The essential enzyme ribonucleotide reductase (RNR) is highly regulated both at the level of overall activity and substrate specificity. Studies of class I, aerobic RNRs have shown that overall activity is downregulated by the binding of dATP to a sm
Externí odkaz:
https://doaj.org/article/de0fb2415a274c318ff68f735ff3b807
Autor:
Inna Rozman Grinberg, Daniel Lundin, Mahmudul Hasan, Mikael Crona, Venkateswara Rao Jonna, Christoph Loderer, Margareta Sahlin, Natalia Markova, Ilya Borovok, Gustav Berggren, Anders Hofer, Derek T Logan, Britt-Marie Sjöberg
Publikováno v:
eLife, Vol 7 (2018)
Ribonucleotide reductases (RNRs) are key enzymes in DNA metabolism, with allosteric mechanisms controlling substrate specificity and overall activity. In RNRs, the activity master-switch, the ATP-cone, has been found exclusively in the catalytic subu
Externí odkaz:
https://doaj.org/article/b748293d383c40c1839ef9c37f256aa8
Autor:
Iván Muñoz-Gutiérrez, Lizett Ortiz de Ora, Inna Rozman Grinberg, Yuval Garty, Edward A Bayer, Yuval Shoham, Raphael Lamed, Ilya Borovok
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146316 (2016)
The Gram-positive, anaerobic, cellulolytic, thermophile Clostridium (Ruminiclostridium) thermocellum secretes a multi-enzyme system called the cellulosome to solubilize plant cell wall polysaccharides. During the saccharolytic process, the enzymatic
Externí odkaz:
https://doaj.org/article/131a740b896d4fdd81fcbbf0bcaee150
Autor:
Svetlana Petkun, Inna Rozman Grinberg, Raphael Lamed, Sadanari Jindou, Tal Burstein, Oren Yaniv, Yuval Shoham, Linda J.W. Shimon, Edward A. Bayer, Felix Frolow
Publikováno v:
PeerJ, Vol 3, p e1126 (2015)
Non-cellulosomal processive endoglucanase 9I (Cel9I) from Clostridium thermocellum is a modular protein, consisting of a family-9 glycoside hydrolase (GH9) catalytic module and two family-3 carbohydrate-binding modules (CBM3c and CBM3b), separated by
Externí odkaz:
https://doaj.org/article/26351109aec3429e8564b6eb536ca698
Autor:
Maly Levy-Assaraf, Milana Voronov-Goldman, Inna Rozman Grinberg, Gloria Weiserman, Linda J W Shimon, Sadanari Jindou, Ilya Borovok, Bryan A White, Edward A Bayer, Raphael Lamed, Felix Frolow
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56138 (2013)
Ruminococcus flavefaciens is one of the predominant fiber-degrading bacteria found in the rumen of herbivores. Bioinformatic analysis of the recently sequenced genome indicated that this bacterium produces one of the most intricate cellulosome system
Externí odkaz:
https://doaj.org/article/f187045048ea4e4caaa91eabb7fb3d24
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50299 (2012)
Electroendocytosis involves the exposure of cells to pulsed low electric field and is emerging as a complementary method to electroporation for the incorporation of macromolecules into cells. The present study explores the underlying mechanism of ele
Externí odkaz:
https://doaj.org/article/9996eb1ec3d54432b5cd19974bf9af99
Autor:
Daniel Rehling, Emma Rose Scaletti, Inna Rozman Grinberg, Daniel Lundin, Margareta Sahlin, Anders Hofer, Britt-Marie Sjöberg, Pål Stenmark
Publikováno v:
Biochemistry. 61:92-106
Ribonucleotide reductase (RNR) is an essential enzyme with a complex mechanism of allosteric regulation found in nearly all living organisms. Class I RNRs are composed of two proteins, a large α-subunit (R1) and a smaller β-subunit (R2) that exist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61c6d39c35d422422390dbfa20f27e1
https://doi.org/10.1021/acs.biochem.1c00503
https://doi.org/10.1021/acs.biochem.1c00503
Autor:
Lizett Ortiz de Ora, Oren Yaniv, Raphael Lamed, Oded Livnah, Inna Rozman Grinberg, Almog Hershko Rimon, Milana Voronov-Goldman, Edward A. Bayer, Felix Frolow
Publikováno v:
Acta Crystallogr F Struct Biol Commun
A novel member of the family 3 carbohydrate-binding modules (CBM3s) is encoded by a gene (Cthe_0271) in Clostridium thermocellum which is the most highly expressed gene in the bacterium during its growth on several types of biomass substrates. Surpri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5253b77713abb03a7a25a1f60b7888f
https://doi.org/10.1107/s2053230x21002764
https://doi.org/10.1107/s2053230x21002764