Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Inna Rabinovich"'
Autor:
Emmanouil Zacharioudakis, Bogos Agianian, Vasantha Kumar MV, Nikolaos Biris, Thomas P. Garner, Inna Rabinovich-Nikitin, Amanda T. Ouchida, Victoria Margulets, Lars Ulrik Nordstrøm, Joel S. Riley, Igor Dolgalev, Yun Chen, Andre J. H. Wittig, Ryan Pekson, Chris Mathew, Peter Wei, Aristotelis Tsirigos, Stephen W. G. Tait, Lorrie A. Kirshenbaum, Richard N. Kitsis, Evripidis Gavathiotis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Mitofusins regulate mitochondrial fusion. Here the authors identify small molecules that activate or inhibit mitofusins’ activity and modulate mitochondrial fusion and functionality. Inhibition of mitochondrial fusion promotes minority MOMP, caspas
Externí odkaz:
https://doaj.org/article/92fc0c999e924a40a5e55d06aabc43db
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 1, Pp 108-109 (2022)
Externí odkaz:
https://doaj.org/article/6896afe7d53141f391f7b8672898d0a9
Autor:
Inna Rabinovich-Nikitin, Alexandra Blant, Rimpy Dhingra, Lorrie A. Kirshenbaum, Michael P. Czubryt
Publikováno v:
Cells, Vol 11, Iss 14, p 2193 (2022)
Hypoxia exerts broad effects on cardiomyocyte function and viability, ranging from altered metabolism and mitochondrial physiology to apoptotic or necrotic cell death. The transcriptional coactivator peroxisome proliferator-activated receptor gamma c
Externí odkaz:
https://doaj.org/article/e7c80344a1404a80ac77aaaa00c70c18
Autor:
Polina Rabinovich-Toidman, Inna Rabinovich-Nikitin, Assaf Ezra, Beka Barbiro, Hilla Fogel, Inna Slutsky, Beka Solomon
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143420 (2015)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease and it is the most common adult onset neurodegenerative disorder affecting motor neurons. There is currently no effective treatment for ALS and our understanding of the patholog
Externí odkaz:
https://doaj.org/article/9ba59100d7f749ccb8bde0b5b544fa61
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46650 (2012)
The toxicity of amyloid β and tau, the two hallmark proteins in Alzheimer's disease (AD), has been extensively studied individually. Recently new data suggest their possible interactions and synergistic effects in the disease. In this study, we inve
Externí odkaz:
https://doaj.org/article/6c5486f09cbf46ae94dd6ea30f305aa5
Autor:
Rimpy Dhingra, Inna Rabinovich-Nikitin, Sonny Rothman, Matthew Guberman, Hongying Gang, Victoria Margulets, Davinder S. Jassal, Keshav Narayan Alagarsamy, Sanjiv Dhingra, Carla Valenzuela Ripoll, Filio Billia, Abhinav Diwan, Ali Javaheri, Lorrie A. Kirshenbaum
Publikováno v:
Circulation. 146:934-954
Background: Cytokines such as tumor necrosis factor-α (TNFα) have been implicated in cardiac dysfunction and toxicity associated with doxorubicin (DOX). Although TNFα can elicit different cellular responses, including survival or death, the mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee2c93538b6cb4542782bf554a49a2a
https://doi.org/10.1161/circulationaha.121.058411
https://doi.org/10.1161/circulationaha.121.058411
Publikováno v:
Circulation. 145:465-468
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7777341d1973e5ffd6d9a67f2039421
https://doi.org/10.1161/circulationaha.121.058402
https://doi.org/10.1161/circulationaha.121.058402
Publikováno v:
Canadian journal of physiology and pharmacology.
Cardiovascular disease is the leading cause of morbidity and mortality worldwide. However, sex differences can impact differently the etiology and outcome of cardiovascular disease when comparing men and women. Women have unique genetic and hormonal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf265bb9408cf51c8f274c44dac304b1
https://pubmed.ncbi.nlm.nih.gov/36318826
https://pubmed.ncbi.nlm.nih.gov/36318826
Autor:
Czubryt, Inna Rabinovich-Nikitin, Alexandra Blant, Rimpy Dhingra, Lorrie A. Kirshenbaum, Michael P.
Publikováno v:
Cells; Volume 11; Issue 14; Pages: 2193
Hypoxia exerts broad effects on cardiomyocyte function and viability, ranging from altered metabolism and mitochondrial physiology to apoptotic or necrotic cell death. The transcriptional coactivator peroxisome proliferator-activated receptor gamma c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::16143a6840382fbf52eaaedbd3f8f175
Autor:
David Friedman, Tami A. Martino, Iman S. Aziz, Lorrie A. Kirshenbaum, Inna Rabinovich-Nikitin, Adam M. McMahon
Publikováno v:
Current Opinion in Pharmacology. 57:60-70
Circadian rhythms follow a 24 h day and night cycle, regulate vital physiological processes, and are especially relevant to cardiovascular growth, renewal, repair, and remodeling. A recent flurry of clinical and experimental studies reveals a profoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6caec8de68ffc5b6a1fc377cf7d7db5e
https://doi.org/10.1016/j.coph.2020.11.007
https://doi.org/10.1016/j.coph.2020.11.007