Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Inna P. Tsypysheva"'
Autor:
J. Daniel García-García, E. Patricia Segura-Ceniceros, Radik A. Zaynullin, Raikhana V. Kunakova, Guzel F. Vafina, Inna P. Tsypysheva, Alejandra I. Vargas-Segura, Anna Ilyina
Publikováno v:
Toxicology Reports, Vol 6, Iss , Pp 862-868 (2019)
In vitro acetylcholinesterase (AChE) inhibition was studied using novel derivatives of (―)-cytisine derivatives N-allylcytisine-12-carbamide (A-63), cytisine-12-carbamide (A-36), N-1-adamantylcytisine-12-thiocarbamide (U-12), and 1-hydroxyquinopima
Externí odkaz:
https://doaj.org/article/158f83fb9de84d07b038e34a262b6e74
Autor:
A. V. Shapovalov, Inna P. Tsypysheva, Alexander F. Smol'yakov, A. V. Koval’skaya, P. R. Petrova, A. A. Lashakov
Publikováno v:
Pharmaceutical Chemistry Journal. 54:654-658
X-ray diffraction measurements and quantum-chemical calculations of the crystal structures of nitromethylcytisines were performed. N-allylamide-9-nitrocytisine (III) was compared to previously studied N-methyl-9-nitrocytisine (II). The crystal struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4381acf3872fa1dd756bf4f978ea4d3
https://doi.org/10.1007/s11094-020-02253-4
https://doi.org/10.1007/s11094-020-02253-4
Publikováno v:
Chemistry of Natural Compounds. 56:892-895
Cytotoxicities of the quinolizidine alkaloid (–)-cytisine and 19 of its derivatives with substituents in the 3-, 9-, and 11-positions were assessed against A431 (epidermal carcinoma), A375 (melanoma), and HCT 116 (colorectal carcinoma) tumor cell l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17989d274d82d7ce30ee403155c66815
https://doi.org/10.1007/s10600-020-03177-x
https://doi.org/10.1007/s10600-020-03177-x
Autor:
P. R. Petrova, Inna P. Tsypysheva, Svetlana V. Osintseva, A. V. Koval’skaya, Alexander F. Smol'yakov, E. A. Mamin
Publikováno v:
Russian Chemical Bulletin. 69:148-157
The crystal packings of mono- (1) and dinitro derivatives (3) of methylcytizine are analyzed in terms of combined geometric and energy approaches and based on the evaluation of the degree of molecular deformation (a decrease in the molecular volume)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30d82e5384d9e24d4951b36f0e0c5de8
https://doi.org/10.1007/s11172-020-2736-4
https://doi.org/10.1007/s11172-020-2736-4
Publikováno v:
Chemistry of Natural Compounds. 56:1183-1185
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78a7cd05b6e67d2d16eb1d6669136826
https://doi.org/10.1007/s10600-020-03263-0
https://doi.org/10.1007/s10600-020-03263-0
Publikováno v:
Chemistry of Natural Compounds. 55:1101-1105
Iodination of the 2-pyridone core of (–)-cytisine and methylcytisine by one equivalent of ICl or N-iodosuccinimide (NIS) in acidic solution gave primarily the 9-iodo derivatives although the starting alkaloid was incompletely converted. Use of an e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d789bbd2550ca5efa800f9700db7909c
https://doi.org/10.1007/s10600-019-02904-3
https://doi.org/10.1007/s10600-019-02904-3
Publikováno v:
Chemistry of Natural Compounds. 55:1106-1109
New (–)-cytisine derivatives were synthesized by conjugating 9- and 11-halo-substituted cytisines with 1′-N-methylurocanic acid using N-hydroxysuccinimide.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26d8d80e047fc3840dcba6fbb83ca8df
https://doi.org/10.1007/s10600-019-02905-2
https://doi.org/10.1007/s10600-019-02905-2
Publikováno v:
Chemistry of Natural Compounds. 55:1110-1114
Guanidine derivatives of the quinolizidine alkaloid methylcytisine were synthesized by converting its 9-amino-derivative into the corresponding thiocarboxamide using phenylisothiocyanate and then into trisubstituted guanidines using HgCl2 in the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c14df0c9ef94a85638b38e60b76e5e3
https://doi.org/10.1007/s10600-019-02906-1
https://doi.org/10.1007/s10600-019-02906-1
Publikováno v:
Chemistry of Natural Compounds. 55:908-913
9-Carboxamide derivatives of the quinolizidine alkaloid methylcytisine were synthesized. The synthetic pathway included nitration-reduction according to the literature that resulted in 9-amination of the 2-pyridone core of the starting alkaloid. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c2ecb85162bf64d6140405f96403206
https://doi.org/10.1007/s10600-019-02843-z
https://doi.org/10.1007/s10600-019-02843-z
Autor:
T. A. Sapozhnikova, A. V. Koval’skaya, Inna P. Tsypysheva, P. R. Petrova, Alexander N. Lobov, N. S. Makara, F. S. Zarudii, S. F. Gabdrakhmanova
Publikováno v:
Natural Product Research. 35:207-215
Novel derivatives of 4-oxo-3-methylcytisine with phenyl moiety bonded to starting molecule through various spacers were obtained from the 9-amino, -halo, -formyl and 11-halo precursors by reductive alkylation of amines, generation of amide, as well a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c8d36eebc06ac4473dc226442f69f2e
https://doi.org/10.1080/14786419.2019.1622106
https://doi.org/10.1080/14786419.2019.1622106