Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Inna Naroditsky"'
Autor:
Maram Hilwi, Katherina Shulman, Inna Naroditsky, Sari Feld, Miriam Gross-Cohen, Ilanit Boyango, Soaad Soboh, Olga Vornicova, Malik Farhoud, Preeti Singh, Gil Bar-Sela, Hadassah Goldberg, Martin Götte, Andrew D. Sharrocks, Yaoyong Li, Ralph D. Sanderson, Neta Ilan, Israel Vlodavsky
Publikováno v:
Cell Death and Disease, Vol 15, Iss 3, Pp 1-13 (2024)
Abstract Unlike the intense research effort devoted to exploring the significance of heparanase in cancer, very little attention was given to Hpa2, a close homolog of heparanase. Here, we explored the role of Hpa2 in breast cancer. Unexpectedly, we f
Externí odkaz:
https://doaj.org/article/09ad1fee324e44e58f2c01dcb813d1a6
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-14 (2023)
Abstract Heparanase 2 (Hpa2, HPSE2) is a close homolog of heparanase. Hpa2, however, lacks intrinsic heparan sulfate (HS)-degrading activity, the hallmark of heparanase enzymatic activity. Mutations of HPSE2 were identified in patients diagnosed with
Externí odkaz:
https://doaj.org/article/0af987c7bc6545cab4e60ac034148588
Autor:
Itai Margulis, Inna Naroditsky, Miriam Gross-Cohen, Neta Ilan, Israel Vlodavsky, Ilana Doweck
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Activity of the endo-beta-glucuronidase heparanase, capable of cleaving heparan sulfate (HS), is most often elevated in many types of tumors, associating with increased tumor metastasis and decreased patients’ survival. Heparanase is therefore cons
Externí odkaz:
https://doaj.org/article/3811fa0313e445b6aaaa1d233d4d92c3
Autor:
Ilana Doweck, Victoria Kaplan-Cohen, Inna Naroditsky, Edmond Sabo, Neta Ilan, Israel Vlodavsky
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 12, Pp 1055-1061 (2006)
Heparanase is an endoglycosidase that specifically cleaves heparan sulfate (HS) side chains of HS proteoglycans, the major proteoglycans in the extracellular matrix and cell surfaces. Traditionally, heparanase activity was implicated in cellular inva
Externí odkaz:
https://doaj.org/article/67e31dfa21094e7bbc5845030a040c8a
Autor:
Uri Barash, Gil Arvatz, Roy Farfara, Inna Naroditsky, Ilana Doweck, Sari Feld, Ofer Ben-Izhak, Neta Ilan, Ofer Nativ, Israel Vlodavsky
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51494 (2012)
T5 is a novel splice variant of heparanase, an endo-β-D-glucuronidase capable of cleaving heparan sulfate side chains at a limited number of sites. T5 splice variant is endowed with pro-tumorigenic properties, enhancing cell proliferation, anchorage
Externí odkaz:
https://doaj.org/article/55a509a510c44ac3a165a6065e6f2cdb
Autor:
Israel Vlodavsky, Neta Ilan, Inna Naroditsky, Uri Barash, Gil Arvatz, Peleg Hasson, Gera Neufeld, Ilana Doweck, Sari Feld, Miriam Gross-Cohen
The endoglycosidase heparanase specifically cleaves the heparan sulfate (HS) side chains on proteoglycans, an activity that has been implicated strongly in tumor metastasis and angiogenesis. Heparanase-2 (Hpa2) is a close homolog of heparanase that l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad4f194adb861cc3cb9780ecd0559223
https://doi.org/10.1158/0008-5472.c.6508343.v1
https://doi.org/10.1158/0008-5472.c.6508343.v1
Autor:
Israel Vlodavsky, Neta Ilan, Inna Naroditsky, Uri Barash, Gil Arvatz, Peleg Hasson, Gera Neufeld, Ilana Doweck, Sari Feld, Miriam Gross-Cohen
Comparable Hpa2 levels in FaDu cell clones and patients' biopsies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5598f95c73efdf2cb0c596c22d06104f
https://doi.org/10.1158/0008-5472.22411982.v1
https://doi.org/10.1158/0008-5472.22411982.v1
Supplementary Figure 5 from Heparanase Augments Epidermal Growth Factor Receptor Phosphorylation: Correlation with Head and Neck Tumor Progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29af1af988b782dc74de52fecd5a990e
https://doi.org/10.1158/0008-5472.22377204
https://doi.org/10.1158/0008-5472.22377204
Supplementary Figure 3 from Heparanase Augments Epidermal Growth Factor Receptor Phosphorylation: Correlation with Head and Neck Tumor Progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10172c5698fd7b40a894d3dba307d168
https://doi.org/10.1158/0008-5472.22377210.v1
https://doi.org/10.1158/0008-5472.22377210.v1
Autor:
Israel Vlodavsky, Neta Ilan, Ilana Doweck, Maayan Gruber, Edward Hammond, Inna Naroditsky, Ilanit Boyango, Anna Shteingauz
Supplementary Figure S3. PTEN and TSC do not localizes to acidic vesicles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b2057eb2d7724ade901e5c8471db0a
https://doi.org/10.1158/0008-5472.22404765.v1
https://doi.org/10.1158/0008-5472.22404765.v1