Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Inna Bendikov"'
Autor:
Guy Levkovich, Dana Almagor, Ganesan Saibaba, Inna Bendikov-Bar, Mark Rusal, Dmitri Lokshtanov, Dmitri Shinder, Dror Sagi
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Cytokines are secreted immunomodulators that are key regulators of the avian immune response. Currently, the most commonly used method to follow cytokine expression is qPCR, which measures cellular levels of mRNA, rather their extracellular circulati
Externí odkaz:
https://doaj.org/article/859ee118344b480e988705ad3cf4f573
Publikováno v:
The journals of gerontology. Series A, Biological sciences and medical sciences. 76(10)
Aging in vertebrates is an extremely complex process that is still poorly understood. One confining factor to studying vertebrate aging is the lack of appropriate models. The laying hen is a good model to study vertebrate aging, as it can be maintain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc49e1cce36976ab35ffebc77bae570
https://pubmed.ncbi.nlm.nih.gov/33978733
https://pubmed.ncbi.nlm.nih.gov/33978733
Publikováno v:
Gaucher Disease: Basic and Clinical Perspectives. :140-157
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6abcffc097108db3a8095c954c5be583
https://doi.org/10.2217/ebo.12.298
https://doi.org/10.2217/ebo.12.298
Publikováno v:
Blood Cells, Molecules & Diseases
Gaucher disease (GD) is characterized by accumulation of glucosylceramide in lysosomes due to mutations in the GBA1 gene encoding the lysosomal hydrolase β-glucocerebrosidase (GCase). The disease has a broad spectrum of phenotypes, which were divide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434104fc4f54a2b95498478b6b19b103
http://europepmc.org/articles/PMC3547170
http://europepmc.org/articles/PMC3547170
Autor:
Mia Horowitz, Inna Bendikov-Bar
Publikováno v:
Human Mutation. 33:1398-1407
Mutations in the GBA gene, encoding the lysosomal acid beta-glucocerebrosidase (GCase), lead to deficient activity of the enzyme in the lysosomes, to glucosylceramide accumulation and to development of Gaucher disease (GD). More than 280 mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e003ad5aa769b04a75cd83a7121fb5e
https://doi.org/10.1002/humu.22124
https://doi.org/10.1002/humu.22124
Publikováno v:
Blood Cells, Molecules, and Diseases. 46:4-10
A large number of mutations in the glucocerebrosidase gene (GBA gene), encoding the lysosomal acid hydrolase glucocerebrosidase (GCase), lead to Gaucher disease (GD). The second most prevalent GD causing mutation, carried by 38% of non-Jewish patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::705cf05daa53875505896a5cd462e3e1
https://doi.org/10.1016/j.bcmd.2010.10.012
https://doi.org/10.1016/j.bcmd.2010.10.012
Autor:
Yoshio Misumi, Elena Dumin, Veronika N. Foltyn, Herman Wolosker, Elena Kartvelishvily, Yukio Ikehara, Inna Bendikov
Publikováno v:
Journal of Biological Chemistry. 281:20291-20302
Mammalian serine racemase is a brain-enriched enzyme that converts L- into D-serine in the nervous system. D-Serine is an endogenous co-agonist at the "glycine site" of N-methyl D-aspartate (NMDA) receptors that is required for the receptor/channel o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a064316cbaadf27e889cfe3f25ddb0
https://doi.org/10.1074/jbc.m601971200
https://doi.org/10.1074/jbc.m601971200
Autor:
Joari De Miranda, Herman Wolosker, Veronika N. Foltyn, Michael D. Toney, Inna Bendikov, Elena Dumin, Elena Kartvelishvily, Pu Li, Rogerio Panizzutti, Maria Shleper
Publikováno v:
Journal of Biological Chemistry. 280:1754-1763
Mammalian brain contains high levels of d-serine, an endogenous co-agonist of N-methyl D-aspartate type of glutamate receptors. D-Serine is synthesized by serine racemase, a brain enriched enzyme converting L- to D-serine. Degradation of D-serine is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::220348e9c77016c66d72ade99a8901cc
https://doi.org/10.1074/jbc.m405726200
https://doi.org/10.1074/jbc.m405726200
Autor:
Herman Wolosker, Rogerio Panizzutti, Galila Agam, Carmit Nadri, Joari De Miranda, Shirly Amar, Inna Bendikov
Publikováno v:
Schizophrenia research. 90(1-3)
Clinical trials demonstrated that D-serine administration improves schizophrenia symptoms, raising the possibility that altered levels of endogenous D-serine may contribute to the N-methyl D-aspartate receptor hypofunction thought to play a role in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb3bc368b1b5575bb68b18f45143801
https://pubmed.ncbi.nlm.nih.gov/17156977
https://pubmed.ncbi.nlm.nih.gov/17156977
Autor:
Rogerio Panizzutti, Herman Wolosker, Inna Bendikov, Carmit Nadri, Shirly Amar, Galila Agam, J. De Miranda
Publikováno v:
European Neuropsychopharmacology. 16:S10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::808ff9add5d4b7f050da3085364332d5
https://doi.org/10.1016/s0924-977x(06)80013-1
https://doi.org/10.1016/s0924-977x(06)80013-1