Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Inna A. Pyshnaya"'
Publikováno v:
Applied Sciences, Vol 13, Iss 12, p 7324 (2023)
Understanding the patterns of noncovalent adsorption of double-stranded nucleic acids (dsDNA) on gold nanoparticles (GNPs) was the aim of this study. It was found that the high-affinity motifs in DNA can and do act as an “anchor” for the fixation
Externí odkaz:
https://doaj.org/article/660ee7b1d3094f2bac7a2fdc59f5bbd9
Autor:
Anna V. Epanchintseva, Julia E. Poletaeva, Dmitrii V. Pyshnyi, Elena I. Ryabchikova, Inna A. Pyshnaya
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 10, Iss 1, Pp 2568-2578 (2019)
Gold nanoparticles (AuNPs) are a platform for the creation of nanoconstructions that can have a variety of functions, including the delivery of therapeutic nucleic acids. We previously designed a AuNP/small interfering RNA (siRNA) nanoconstruction co
Externí odkaz:
https://doaj.org/article/1890ed82c488452480fa6a658598a978
Autor:
Anna V. Epanchintseva, Julia E. Poletaeva, Anton S. Dome, Ilya S. Dovydenko, Inna A. Pyshnaya, Elena I. Ryabchikova
Publikováno v:
Nanomaterials, Vol 12, Iss 24, p 4450 (2022)
Small interfering RNAs (siRNAs) are a powerful tool for specific suppression of protein synthesis in the cell, and this determines the attractiveness of siRNAs as a drug. Low resistance of siRNA to nucleases and inability to enter into target cells a
Externí odkaz:
https://doaj.org/article/1806a074a2184afbb569906a88d07243
Autor:
Asya S. Levina, Marina N. Repkova, Nadezhda V. Shikina, Zinfer R. Ismagilov, Svetlana A. Yashnik, Dmitrii V. Semenov, Yulia I. Savinovskaya, Natalia A. Mazurkova, Inna A. Pyshnaya, Valentina F. Zarytova
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 9, Iss 1, Pp 2516-2525 (2018)
The development of efficient and convenient systems for the delivery of nucleic-acid-based drugs into cells is an urgent task. А promising approach is the use of various nanoparticles. Silica nanoparticles can be used as vehicles to deliver nucleic
Externí odkaz:
https://doaj.org/article/a57be39717044e968750721fa123f851
Autor:
Anna V. Epanchintseva, Julia E. Poletaeva, Ilya S. Dovydenko, Boris P. Chelobanov, Dmitrii V. Pyshnyi, Elena I. Ryabchikova, Inna A. Pyshnaya
Publikováno v:
Nanomaterials, Vol 11, Iss 11, p 2775 (2021)
There is an urgent need to develop systems for nucleic acid delivery, especially for the creation of effective therapeutics against various diseases. We have previously shown the feasibility of efficient delivery of small interfering RNA by means of
Externí odkaz:
https://doaj.org/article/f0e5ea8054c849ac95ad2f10fdc5d8b2
Autor:
Anna S. Pavlova, Kristina I. Yakovleva, Anna V. Epanchitseva, Maxim S. Kupryushkin, Inna A. Pyshnaya, Dmitrii V. Pyshnyi, Elena I. Ryabchikova, Ilya S. Dovydenko
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9784 (2021)
Small interfering RNA (siRNA) is the most important tool for the manipulation of mRNA expression and needs protection from intracellular nucleases when delivered into the cell. In this work, we examined the effects of siRNA modification with the phos
Externí odkaz:
https://doaj.org/article/7f0c34d184c646f199da3956a582d2eb
Autor:
Anna V. Epanchintseva, Ekaterina A. Gorbunova, Elena I. Ryabchikova, Inna A. Pyshnaya, Dmitrii V. Pyshnyi
Publikováno v:
Nanomaterials, Vol 11, Iss 5, p 1178 (2021)
Fluorophore (FD) labeling is widely used for detection and quantification of various compounds bound to nanocarriers. The systems, composed of gold nanoparticles (GNPs) and oligonucleotides (ONs) labeled with FDs, have wide applications. Our work was
Externí odkaz:
https://doaj.org/article/3ae559a9d1544f018ede0dac51ada5ff
Autor:
Maria Y. Konoshenko, Evgeniy A. Lekchnov, Olga E. Bryzgunova, Elena Kiseleva, Inna A. Pyshnaya, Pavel P. Laktionov
Publikováno v:
Diagnostics, Vol 11, Iss 3, p 384 (2021)
Extracellular vesicles (EVs) have high potential as sources of biomarkers for non-invasive diagnostics. Thus, a simple and productive method of EV isolation is demanded for certain scientific and medical applications of EVs. Here we aim to develop a
Externí odkaz:
https://doaj.org/article/67bed27da6b2477ebcebe33661121721
Autor:
Tatyana V. Popova, Inna A. Pyshnaya, Olga D. Zakharova, Andrey E. Akulov, Oleg B. Shevelev, Julia Poletaeva, Evgenii L. Zavjalov, Vladimir N. Silnikov, Elena I. Ryabchikova, Tatyana S. Godovikova
Publikováno v:
Biomedicines, Vol 9, Iss 1, p 74 (2021)
Multifunctional gold nanoparticles (AuNPs) may serve as a scaffold to integrate diagnostic and therapeutic functions into one theranostic system, thereby simultaneously facilitating diagnosis and therapy and monitoring therapeutic responses. Herein,
Externí odkaz:
https://doaj.org/article/a75b36523d7a439ba4b95e233a31bc89
Autor:
Larisa I. Karpenko, Andrey P. Rudometov, Sergei V. Sharabrin, Dmitry N. Shcherbakov, Mariya B. Borgoyakova, Sergei I. Bazhan, Ekaterina A. Volosnikova, Nadezhda B. Rudometova, Lyubov A. Orlova, Inna A. Pyshnaya, Boris N. Zaitsev, Natalya V. Volkova, Mamedyar Sh. Azaev, Anna V. Zaykovskaya, Oleg V. Pyankov, Alexander A. Ilyichev
Publikováno v:
Vaccines, Vol 9, Iss 2, p 76 (2021)
One of the key stages in the development of mRNA vaccines is their delivery. Along with liposome, other materials are being developed for mRNA delivery that can ensure both the safety and effectiveness of the vaccine, and also facilitate its storage
Externí odkaz:
https://doaj.org/article/96c4c28d3711457dacda9271f9dcb895