Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Inna, Vainshtein"'
Autor:
Nan Zhang, Ming Liang Chan, Jing Li, Philip Z. Brohawn, Bo Sun, Inna Vainshtein, Lorin K. Roskos, Raffaella Faggioni, Rada M. Savic
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 12, Pp 1945-1959 (2023)
Abstract Pharmacometric models were used to investigate the utility of biomarkers in predicting the efficacy (Crohn's Disease Activity Index [CDAI]) of brazikumab and provide a data‐driven framework for precision therapy for Crohn's disease (CD). I
Externí odkaz:
https://doaj.org/article/11606fed40ee4aa09927036592c3a5a3
Autor:
Philip M. Hemken, Nicolette M. Jeanblanc, Tracey Rae, Susan E. Brophy, Maria J. Datwyler, Ying Xu, T. Scott Manetz, Inna Vainshtein, Meina Liang, Xiaodong Xiao, Partha S. Chowdhury, Chien-ying Chang, Katie Streicher, Lydia Greenlees, Koustubh Ranade, Gerard J. Davis
Publikováno v:
Practical Laboratory Medicine, Vol 9, Iss , Pp 58-68 (2017)
Background: Dipeptidyl peptidase-4 (DPP-4) may be a suitable biomarker to identify people with severe asthma who have greater activation of the interleukin-13 (IL-13) pathway and may therefore benefit from IL-13-targeted treatments. We report the ana
Externí odkaz:
https://doaj.org/article/b5d2f2e9efc14bc1853381f654d6d33b
Autor:
Jackie Cheng, Meina Liang, Miguel F. Carvalho, Natalie Tigue, Raffaella Faggioni, Lorin K. Roskos, Inna Vainshtein
Publikováno v:
Antibodies, Vol 9, Iss 3, p 49 (2020)
Amplification and overexpression of HER2 (human epidermal growth factor receptor 2), an ErbB2 receptor tyrosine kinase, have been implicated in human cancer and metastasis. A bispecific tetravalent anti-HER2 antibody (anti-HER2-Bs), targeting two non
Externí odkaz:
https://doaj.org/article/d23b66fb5b1140e39792ceb15857ee05
Autor:
Darshana Jani, Robin Marsden, Michele Gunsior, Laura Schild Hay, Bethany Ward, Kyra J. Cowan, Mitra Azadeh, Breann Barker, Liching Cao, Kristin R. Closson, Kelly Coble, Sanjay L. Dholakiya, Julie Dusseault, Amanda Hays, Carina Herl, Michael E. Hodsdon, Susan C. Irvin, Susan Kirshner, Gerry Kolaitis, Nadia Kulagina, Seema Kumar, Ching Ha Lai, Francesco Lipari, Susana Liu, Keith D. Merdek, Ioana R. Moldovan, Reza Mozaffari, Luying Pan, Corina Place, Veerle Snoeck, Marta Starcevic Manning, Dennis Stocker, Magdalena Tary-Lehmann, Amy Turner, Inna Vainshtein, Daniela Verthelyi, William T. Williams, Haoheng Yan, Weili Yan, Lili Yang, Lin Yang, Jennifer Zemo, Zhandong Don Zhong
Publikováno v:
The AAPS journalReferences. 24(6)
A clear scientific and operational need exists for harmonized bioanalytical immunogenicity study reporting to facilitate communication of immunogenicity findings and expedient review by industry and health authorities. To address these key bioanalyti
Publikováno v:
The AAPS Journal. 23
Tovetumab (MEDI-575) is a fully human IgG2κ monoclonal antibody that specifically binds to human platelet-derived growth factor receptor alpha (PDGFRα) and blocks receptor signal transduction by PDGF ligands. The affinity of tovetumab determined us
Autor:
Deepa Bhojwani, Dennis L. Confer, Terry J. Fry, James A. Whitlock, Sonali Chaudhury, Kirk R. Schultz, Paul L. Martin, Nirali N. Shah, Michael A. Pulsipher, Inna Vainshtein, Alan S. Wayne, Brent L. Wood, Denison Kuruvilla, Alexia Adams, Lewis B. Silverman, Jennifer Schneiderman
Publikováno v:
Pediatric Blood & Cancer. 68
Autor:
Meina Liang, Natalie J. Tigue, Lorin Roskos, Raffaella Faggioni, Jackie Cheng, Miguel F. Carvalho, Inna Vainshtein
Publikováno v:
Antibodies
Volume 9
Issue 3
Antibodies, Vol 9, Iss 49, p 49 (2020)
Volume 9
Issue 3
Antibodies, Vol 9, Iss 49, p 49 (2020)
Amplification and overexpression of HER2 (human epidermal growth factor receptor 2), an ErbB2 receptor tyrosine kinase, have been implicated in human cancer and metastasis. A bispecific tetravalent anti-HER2 antibody (anti-HER2-Bs), targeting two non
Publikováno v:
The AAPS journal. 23(1)
Tovetumab (MEDI-575) is a fully human IgG2κ monoclonal antibody that specifically binds to human platelet-derived growth factor receptor alpha (PDGFRα) and blocks receptor signal transduction by PDGF ligands. The affinity of tovetumab determined us
Autor:
Tanya M. Trippett, Luciano Dalla-Pozza, Alan S. Wayne, Ira Pastan, Jessica Boklan, Yves Bertrand, John Moppett, Meina Liang, Francoise Mechinaud, Paul L. Martin, Susan R. Rheingold, Claudine Schmitt, Franco Locatelli, Robyn M. Dennis, André Baruchel, Inna Vainshtein, Nirali N. Shah, Keith J. August, Nobuko Hijiya, Deepa Bhojwani, Kemal Balic, Xia Li, Nai Shun Yao
Publikováno v:
Pediatr Blood Cancer
Background In a multicenter phase 1 study of children with relapsed/refractory acute lymphoblastic leukemia (ALL), moxetumomab pasudotox, an anti-CD22 immunotoxin, demonstrated a manageable safety profile and preliminary evidence of clinical activity
Autor:
Martin Schwickart, Inna Vainshtein
Publikováno v:
Nijkamp and Parnham's Principles of Immunopharmacology ISBN: 9783030108090
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba4bd095a50e7ed7d5bbce1f84d2d405
https://doi.org/10.1007/978-3-030-10811-3_15
https://doi.org/10.1007/978-3-030-10811-3_15