Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Inna, Radzishevsky"'
Autor:
Oluwarotimi O. Folorunso, Stephanie E. Brown, Jugajyoti Baruah, Theresa L. Harvey, Shekib A. Jami, Inna Radzishevsky, Herman Wolosker, James M. McNally, John A. Gray, Anju Vasudevan, Darrick T. Balu
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The proper development and function of telencephalic GABAergic interneurons is critical for maintaining the excitation and inhibition (E/I) balance in cortical circuits. Glutamate contributes to cortical interneuron (CIN) development via N-m
Externí odkaz:
https://doaj.org/article/c1a3de421db14b62abea4c8f005bf011
Autor:
Eva Ploux, Valentine Bouet, Inna Radzishevsky, Herman Wolosker, Thomas Freret, Jean-Marie Billard
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9447 (2020)
d-serine is the major co-agonist of N-methyl-D-aspartate receptors (NMDAR) at CA3/CA1 hippocampal synapses, the activation of which drives long-term potentiation (LTP). The use of mice with targeted deletion of the serine racemase (SR) enzyme has bee
Externí odkaz:
https://doaj.org/article/9f3e3b400fd7471d9e9cbecd25744db0
Autor:
Stephen A. Tapanes, Dena Arizanovska, Madelen M. Díaz, Oluwarotimi O. Folorunso, Theresa Harvey, Stephanie E. Brown, Inna Radzishevsky, Liesl N. Close, Jonathan R. Jagid, Joacir Graciolli Cordeiro, Herman Wolosker, Darrick T. Balu, Daniel J. Liebl
Publikováno v:
Glia. 70:1133-1152
Synaptic damage is one of the most prevalent pathophysiological responses to traumatic CNS injury and underlies much of the associated cognitive dysfunction; however, it is poorly understood. The D-amino acid, D-serine, serves as the primary co-agoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c18fbf3679c0df285f31eacd69680012
https://doi.org/10.1002/glia.24161
https://doi.org/10.1002/glia.24161
Autor:
Marialaura Marchetti, Hazem Safory, Shai Kellner, Simone Engelender, Shai Berlin, Inna Radzishevsky, Veronika N. Foltyn, Samah Neame, Francesco Marchesani, Ayelet Touitou, Jean-Marie Billard, Herman Wolosker
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (41), pp.20736-20742. ⟨10.1073/pnas.1909458116⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (41), pp.20736-20742. ⟨10.1073/pnas.1909458116⟩
Astrocytes express the 3-phosphoglycerate dehydrogenase (Phgdh) enzyme required for the synthesis of l-serine from glucose. Astrocytic l-serine was proposed to regulate NMDAR activity by shuttling to neurons to sustain d-serine production, but this h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907772d4c795daf274edd8133a3fc20f
https://doi.org/10.1073/pnas.1909458116
https://doi.org/10.1073/pnas.1909458116
Autor:
Inna Radzishevsky, Herman Wolosker
Publikováno v:
The Biochemical journal. 478(5)
Promiscuous catalysis is a common property of enzymes, particularly those using pyridoxal 5′-phosphate as a cofactor. In a recent issue of this journal, Katane et al. Biochem. J. 477, 4221–4241 demonstrate the synthesis and accumulation of d-glut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feeb098df559cd41726cc3e0bc605664
https://pubmed.ncbi.nlm.nih.gov/33079132
https://pubmed.ncbi.nlm.nih.gov/33079132
Autor:
Kevin Muszynski, Kerry J. Ressler, Joseph T. Coyle, Kendall Taylor Presti, Inna Radzishevsky, Darrick T. Balu, Cathy C.Y. Huang, Herman Wolosker, Guia Guffanti
Publikováno v:
Biological Psychiatry. 83:273-283
Background The amygdala is a central component of the neural circuitry that underlies fear learning. N-methyl-D-aspartate receptor–dependent plasticity in the amygdala is required for pavlovian fear conditioning and extinction. N-methyl-D-aspartate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9c383a505f07463d74afb12d850103
https://doi.org/10.1016/j.biopsych.2017.08.012
https://doi.org/10.1016/j.biopsych.2017.08.012
Autor:
Mor Savyon, Fatimah Abd Elghani, Ruth Rott, Kah-Leong Lim, Tsipora Cohen, Rina Bandopadhyay, Ninghan Wang, Raymonde Szargel, Simone Engelender, Vered Shani, Lihi Shaulov, Christopher A. Ross, Hazem Safory, Hui Zhang, Inna Radzishevsky, Haya Hamza
Publikováno v:
Hum Mol Genet
Mutations in LRRK2 cause autosomal dominant and sporadic Parkinson’s disease, but the mechanisms involved in LRRK2 toxicity in PD are yet to be fully understood. We found that LRRK2 translocates to the nucleus by binding to seven in absentia homolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65005dcf0714e9df0168b83894528018
https://pubmed.ncbi.nlm.nih.gov/31626293
https://pubmed.ncbi.nlm.nih.gov/31626293
Autor:
Ellie Shahbo, Darrick T. Balu, Jugajyoti Baruah, Anju Vasudevan, Ismail Ajjawi, Oluwarotimi Folorunso, Theresa L. Harvey, Herman Wolosker, Inna Radzishevsky
Publikováno v:
Biological Psychiatry. 89:S117
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b62f59168e323a03fc1ff0d4c3f2e99
https://doi.org/10.1016/j.biopsych.2021.02.303
https://doi.org/10.1016/j.biopsych.2021.02.303
Autor:
Valentine Bouet, Herman Wolosker, Thomas Freret, Inna Radzishevsky, Eva Ploux, Jean-Marie Billard
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2020, 21 (24), pp.9447. ⟨10.3390/ijms21249447⟩
International Journal of Molecular Sciences, Vol 21, Iss 9447, p 9447 (2020)
Volume 21
Issue 24
International Journal of Molecular Sciences, MDPI, 2020, 21 (24), pp.9447. ⟨10.3390/ijms21249447⟩
International Journal of Molecular Sciences, Vol 21, Iss 9447, p 9447 (2020)
Volume 21
Issue 24
d-serine is the major co-agonist of N-methyl-D-aspartate receptors (NMDAR) at CA3/CA1 hippocampal synapses, the activation of which drives long-term potentiation (LTP). The use of mice with targeted deletion of the serine racemase (SR) enzyme has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6066e661947f246b05548dd027f2b59
https://doi.org/10.3390/ijms21249447
https://doi.org/10.3390/ijms21249447
Autor:
Elena Dumin, Hazem Safory, Dina Rosenberg, Herman Wolosker, Hisashi Mori, Inna Radzishevsky, Goren Kolodney
Publikováno v:
Journal of Biological Chemistry. 290:31037-31050
D-Serine is a physiological co-agonist that activates N-methyl D-aspartate receptors (NMDARs) and is essential for neurotransmission, synaptic plasticity, and behavior. D-Serine may also trigger NMDAR-mediated neurotoxicity, and its dysregulation may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dd67ce9d6c0a6b75ff37df4edc89ef2
https://doi.org/10.1074/jbc.m115.699496
https://doi.org/10.1074/jbc.m115.699496