Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Inn-Oc Han"'
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract This study investigated the role of O-GlcNAc cycling in Alzheimer’s disease-related changes in brain pathophysiology induced by chronic REM sleep deprivation (CSD) in mice. CSD increased amyloid beta (Aβ) and p-Tau accumulation and impair
Externí odkaz:
https://doaj.org/article/abc0ea6f7dde469697c1ff0ae81eb59e
Protective effect of increased O-GlcNAc cycling against 6-OHDA induced Parkinson’s disease pathology
Publikováno v:
Cell Death and Disease, Vol 15, Iss 4, Pp 1-12 (2024)
Abstract This study aimed to elucidate the role of O-GlcNAc cycling in 6-hydroxydopamine (6-OHDA)-induced Parkinson’s disease (PD)-like neurodegeneration and the underlying mechanisms. We observed dose-dependent downregulation of O-GlcNAcylation, a
Externí odkaz:
https://doaj.org/article/bbbe2971362b40a5bf2d782c633a2894
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-20 (2023)
Abstract This study investigated chronic and repeated sleep deprivation (RSD)-induced neuronal changes in hexosamine biosynthetic pathway/O-linked N-acetylglucosamine (HBP/O-GlcNAc) cycling of glucose metabolism and further explored the role of alter
Externí odkaz:
https://doaj.org/article/1f80242c46a64c2ab0ff1871f8635702
Autor:
So-Young Hwang, Jae-Seob Jung, Tae-Hyun Kim, Soo-Jeong Lim, Eok-Soo Oh, Joo-Young Kim, Kyung-Ae Ji, Eun-Hye Joe, Kwan-Ho Cho, Inn-Oc Han
Publikováno v:
Neurobiology of Disease, Vol 21, Iss 3, Pp 457-467 (2006)
The aim of this study was to investigate the role of microglia in radiation-induced astrocyte gliosis. We found that a single dose of 15 Gy radiation to a whole rat brain increased immunostaining of glial fibrillary acidic protein in astrocytes 6 h l
Externí odkaz:
https://doaj.org/article/66c4cca5f21e4112849ca98fc12e5928
Publikováno v:
American Journal of Physiology: Cell Physiology; Mar2024, Vol. 326 Issue 3, pC978-C989, 12p
Publikováno v:
American Journal of Physiology: Cell Physiology; Oct2023, Vol. 325 Issue 4, pC981-C998, 18p
Autor:
Hayoung Lee, Kyung-Hwa Lee, Jeong Eun Jeon, Sunhee Jung, Yu Jin Lee, Mi Hyun Lee, Inn-Oc Han, Seong Min Oh, Geum-Sook Hwang
Publikováno v:
Chronobiology in Medicine. 3:75-83
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b73a62739d992b99bd5b67101d35530
https://doi.org/10.33069/cim.2021.0013
https://doi.org/10.33069/cim.2021.0013
Autor:
Jiwon Park, ChiHye Chung, Sang-Min Kim, Thuy-Duong Thi Tran, Hyun Jae Sung, Seungjae Zhang, Inn-Oc Han
Publikováno v:
Neurotherapeutics
Rapid eye movement (REM) sleep is implicated learning and memory (L/M) functions and hippocampal long-term potentiation (LTP). Here, we demonstrate that REM sleep deprivation (REMSD)-induced impairment of contextual fear memory in mouse is linked to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50cc7492aafb6d1926f9addd3dd11fe
https://pubmed.ncbi.nlm.nih.gov/34312767
https://pubmed.ncbi.nlm.nih.gov/34312767
Autor:
Sunhee Jung, Ngan An Bui, Geum-Sook Hwang, Inn-Oc Han, In Young Park, Jiwon Park, Sang-Min Kim
Publikováno v:
J Cereb Blood Flow Metab
Repetitive hypoxia (RH) exposure affects the initiation and progression of cognitive dysfunction, but little is known about the mechanisms of hypoxic brain damage. In this study, we show that sublethal RH increased anxiety, impaired learning and memo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329dcf6d148c5a7520a789b5a09e71b5
https://europepmc.org/articles/PMC8756468/
https://europepmc.org/articles/PMC8756468/
Autor:
Hyeongjin Cho, Inn-Oc Han, Sang-Min Kim, Woojoo Lee, Kyunghyun Nam, Yunkyoung Lee, Jiwon Park
Publikováno v:
The FASEB Journal. 34:853-864
Sleep is an evolutionarily conserved physiological process implicated in the consolidation of learning and memory (L/M). Here, we report that sleep deprivation (SD)-induced cognitive deficits in zebrafish are mediated through reduction in O-GlcNAcyla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d20ffc0e79ac8a7dbc7c8778a41ac7cc
https://doi.org/10.1096/fj.201901399rr
https://doi.org/10.1096/fj.201901399rr