Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Inn Ho Tsai"'
Publikováno v:
Toxins, Vol 15, Iss 7, p 408 (2023)
Trimeresurus gracilis is an endemic alpine pitviper in Taiwan with controversial phylogeny, and its venom proteome remains unknown. In this study, we conducted a proteomic analysis of T. gracilis venom using high-performance liquid chromatography-tan
Externí odkaz:
https://doaj.org/article/e3c65d03406d47fcad80e950639572b1
Publikováno v:
Toxins; Volume 15; Issue 7; Pages: 408
Trimeresurus gracilis is an endemic alpine pitviper in Taiwan with controversial phylogeny, and its venom proteome remains unknown. In this study, we conducted a proteomic analysis of T.gracilis venom using high-performance liquid chromatography-tand
Autor:
Tein-Shun Tsai, Inn-Ho Tsai
Publikováno v:
Toxicon. 225:107053
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 206
Trimeresurus gracilis (Tgc) is endemic to Taiwan and shown to be closely related with Ovophis okinavensis by previous phylogenetic analyses, but their taxonomic status remain controversial. Here, we cloned and sequenced ten of its venom serine-protea
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100354 (2014)
Acutobin isolated from Deinagkistrodon acutus venom has been used to prevent or treat stroke in patients. This defibrinogenating serine protease is a 39 kDa glycoprotein containing terminal disialyl-capped N-glycans. After sialidase treatment, the en
Externí odkaz:
https://doaj.org/article/085ad116d68f416f86161c5db0c33154
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 198
The semi-fossil and pit-less Azemiops feae is possibly the most primitive crotalid species. Here, we have cloned and sequenced cDNAs encoding four serine proteases (vSPs) from the venom glands of Chinese A. feae. Full amino-acid sequences of the majo
Autor:
Su-Xian Yan, Inn-Ho Tsai, Ying-zhe Xie, Jian-cheng Song, Zhe-Zhi Wang, Zhang-Min Yang, Zhen-Zhen Liu
Publikováno v:
Toxicon. 141:65-72
Two acidic Asp49-PLA2s with Glu6 substitution and a neutral Lys49-PLA (designated Gst-K49) were cloned from G. strauchii venom glands, their full amino acid sequences were deduced. The predominant acidic PLA2 (designated Gst-E6a) contains 124 residue
Autor:
Wen-long Zhao, Zhe-Zhi Wang, Cui Zhang, Jian-Zhu Pei, Ying-Ming Wang, Hui Yu, Zhen-Zhen Liu, Yu-E. Yang, Zhang-Min Yang, Su-Xian Yan, Inn-Ho Tsai
Publikováno v:
Journal of Proteomics. 164:19-32
Nine distinct venom serine proteases (vSPs) of Gloydius intermedius were studied by transcriptomic, sub-proteomic and phylogenetic analyses. Their complete amino acid sequences were deduced after Expression Sequence Tag (EST) analyses followed by cDN
Autor:
Cheng Wei Lin, Tsung Han Lin, Ming Ting Lee, Geen-Dong Chang, Wen Hsien Hsu, Pei Hsun Tsai, Chithan C. Kandaswami, Ku Chung Chen, Ying Tang Huang, Inn Ho Tsai, Chia Hsiung Cheng, Chang Jen Huang
Publikováno v:
Food & Function. 8:1558-1568
We previously reported that the dietary flavonoids, luteolin and quercetin, might inhibit the invasiveness of cervical cancer by reversing epithelial-mesenchymal transition (EMT) signaling. However, the regulatory mechanism exerted by luteolin and qu
Publikováno v:
Toxicon. 94:50-59
Acutobin, the α-fibrinogenase from Deinagkistrodon acutus venom, contains four N-glycosylation sites with disialylated complex-typed glycans. Here, we explore the functional roles of each of the N-glycan by site-directed mutagenesis. The wild-type (