Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Inn H"'
Publikováno v:
Methods and Protocols, Vol 7, Iss 5, p 71 (2024)
Polysorbates are the predominant surfactants used to stabilize protein formulations. Unfortunately, polysorbates can undergo hydrolytic degradation, which releases fatty acids that can accumulate to form visible particles. The detection and quantitat
Externí odkaz:
https://doaj.org/article/615abb47b5e249c0b99823afc6148d9f
Autor:
Inn H. Yuk, Theo Koulis, Nidhi Doshi, Kathrin Gregoritza, Constanze Hediger, Vanessa Lebouc-Haefliger, Jamie Giddings, Tarik A. Khan
Publikováno v:
AAPS Open, Vol 8, Iss 1, Pp 1-22 (2022)
Abstract Hydrolytic degradation of the polysorbate 20 (PS20) surfactant in protein-based liquid formulations releases free fatty acids (FFAs), which can accumulate to form particles in drug products during real-time (long-term) storage. To identify f
Externí odkaz:
https://doaj.org/article/309e1482153a44eda5ca7dc1603040aa
Autor:
Gupta, Sanjay K., Graf, Tobias, Edelmann, Franziska T., Seelmann, Helen, Reintinger, Markus, Hillringhaus, Lars, Bergmann, Frank, Wiedmann, Michael, Falkenstein, Roberto, Wegele, Harald, Yuk, Inn H., Leiss, Michael
Publikováno v:
In European Journal of Pharmaceutics and Biopharmaceutics June 2023 187:120-129
Autor:
Kovner, Daniel, Yuk, Inn H., Shen, Amy, Li, Hong, Graf, Tobias, Gupta, Sanjay, Liu, Wenqiang, Tomlinson, Anthony
Publikováno v:
In Journal of Pharmaceutical Sciences May 2023 112(5):1351-1363
Publikováno v:
Methods & Protocols; Oct2024, Vol. 7 Issue 5, p71, 13p
Autor:
Graf, Tobias, Tomlinson, Anthony, Yuk, Inn H., Kufer, Regina, Spensberger, Bernhard, Falkenstein, Roberto, Shen, Amy, Li, Hong, Duan, Dana, Liu, Wenqiang, Wohlrab, Stefanie, Edelmann, Franziska, Leiss, Michael
Publikováno v:
In Journal of Pharmaceutical Sciences November 2021 110(11):3558-3567
Autor:
Yuk, Inn H.1 (AUTHOR), Koulis, Theo2 (AUTHOR), Doshi, Nidhi1 (AUTHOR), Gregoritza, Kathrin3 (AUTHOR), Hediger, Constanze3 (AUTHOR), Lebouc-Haefliger, Vanessa3 (AUTHOR), Giddings, Jamie1 (AUTHOR), Khan, Tarik A.3 (AUTHOR) tarik.khan@roche.com
Publikováno v:
AAPS Open. 11/14/2022, Vol. 8 Issue 1, p1-22. 22p.
Akademický článek
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Autor:
Sanjay K. Gupta, Tobias Graf, Franziska T. Edelmann, Helen Seelmann, Markus Reintinger, Lars Hillringhaus, Frank Bergmann, Michael Wiedmann, Roberto Falkenstein, Harald Wegele, Inn H. Yuk, Michael Leiss
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 187:120-129
Investigation of Metal-Catalyzed Antibody Carbonylation With an Improved Protein Carbonylation Assay
Autor:
Yang, Yi, Mah, Anna, Yuk, Inn H., Grewal, Parbir S., Pynn, Abigail, Cole, Will, Gao, Di, Zhang, Fan, Chen, Jia, Gennaro, Lynn, Schöneich, Christian
Publikováno v:
In Journal of Pharmaceutical Sciences October 2018 107(10):2570-2580