Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Inn Chuan Ng"'
Publikováno v:
Current Research in Toxicology, Vol 2, Iss , Pp 282-295 (2021)
Cell-based in vitro models coupled with high-throughput transcriptomics (HTTr) are increasingly utilized as alternative methods to animal-based toxicity testing. Here, using a panel of 14 chemicals with different risks of human drug-induced liver inj
Externí odkaz:
https://doaj.org/article/da7c2d5fcd91451b9ff67516445a5ea5
Autor:
Junjie Wang, Lisa Tucker-Kellogg, Inn Chuan Ng, Ruirui Jia, P S Thiagarajan, Jacob K White, Hanry Yu
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 6, p e1003573 (2014)
The TGF-β/Smad signaling system decreases its activity through strong negative regulation. Several molecular mechanisms of negative regulation have been published, but the relative impact of each mechanism on the overall system is unknown. In this w
Externí odkaz:
https://doaj.org/article/8614980317a34d449f8021a920999167
Publikováno v:
Current Research in Toxicology
Current Research in Toxicology, Vol 2, Iss, Pp 282-295 (2021)
Current Research in Toxicology, Vol 2, Iss, Pp 282-295 (2021)
Graphical abstract
Highlights • TempO-Seq assays of rat hepatocytes in collagen sandwich are highly reproducible. • Gene expression analysis shows S1500+ is representative of the whole transcriptome. • Connectivity mapping shows consistenc
Highlights • TempO-Seq assays of rat hepatocytes in collagen sandwich are highly reproducible. • Gene expression analysis shows S1500+ is representative of the whole transcriptome. • Connectivity mapping shows consistenc
Autor:
Pearlyn Jia Ying Toh, Yue Zhang, Cornelia Monzel, S. Tamir Rashid, Vidhyalakshmi Acharya, Hanry Yu, Virgile Viasnoff, Jasmine Fei Li Chin, Noémi van Hul, Inn Chuan Ng, Richard De Mets, Soon Seng Ng
Publikováno v:
Nature Materials. 19:1026-1035
The symmetry breaking of protein distribution and cytoskeleton organization is an essential aspect for the development of apicobasal polarity. In embryonic cells this process is largely cell autonomous, while differentiated epithelial cells collectiv
Autor:
Side Liu, Weiguang Qiao, Zelong Han, Yang Yu, Feiyang Huang, Xiaobei Luo, Inn Chuan Ng, Yumeng Xu, Zhenyu Chen, Robby T. Tan, Jiahao Wang, Hanry Yu, Qiang Zhang, Jianqun Cai
Publikováno v:
Gastrointestinal Endoscopy. 94:627-638.e1
Background and Aims Endoscopic submucosal dissection (ESD) and EMR are applied in treating superficial colorectal neoplasms but are contraindicated by deeply invasive colorectal cancer (CRC). The invasion depth of neoplasms can be examined by an auto
Publikováno v:
Seminars in Cell & Developmental Biology. 71:153-167
Liver is highly regenerative as it can restore its function and size even after 70% partial hepatectomy. During liver regeneration, the mechanical and chemical environment of liver is altered with accumulation of various growth factors and remodeling
Autor:
Yue, Zhang, Richard, De Mets, Cornelia, Monzel, Vidhyalakshmi, Acharya, Pearlyn, Toh, Jasmine Fei Li, Chin, Noémi, Van Hul, Inn Chuan, Ng, Hanry, Yu, Soon Seng, Ng, S, Tamir Rashid, Virgile, Viasnoff
Publikováno v:
Nature materials. 19(9)
The symmetry breaking of protein distribution and cytoskeleton organization is an essential aspect for the development of apicobasal polarity. In embryonic cells this process is largely cell autonomous, while differentiated epithelial cells collectiv
Understanding of the interaction between biomaterials and biological systems requires the knowledge of the anatomy and physiology, which relates the structure of an organism to its function. The structure of an organism is classified into different l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::052e0e39af25c8d31d4b5641d8039dc1
https://doi.org/10.1016/b978-0-12-801238-3.99876-3
https://doi.org/10.1016/b978-0-12-801238-3.99876-3
Bile canaliculi (BC) are the smallest vessels of the biliary tree. They are formed from the apical surfaces of adjoining hepatocytes, resulting in lumenal conduits for bile flow. Bile is propelled along the BC by hepatocyte contractions that arise fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab22feed78023060846713f299d9265c
https://doi.org/10.1101/449512
https://doi.org/10.1101/449512
Publikováno v:
Biophysical Journal. 116:376a-377a