Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Inmaculada M. González-González"'
Autor:
Inmaculada M. González-González, John A. Gray, Joana Ferreira, María Jose Conde-Dusman, Delphine Bouchet, Isabel Perez-Otaño, Laurent Groc
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112477- (2023)
Summary: Signaling via N-methyl-d-aspartate receptors (NMDARs) is critical for the maturation of glutamatergic synapses, partly through a developmental switch from immature synapses expressing primarily GluN2B- and GluN3A-containing subtypes to GluN2
Externí odkaz:
https://doaj.org/article/bf9666f4a96d4c7eb23dd56fc77bb8ac
Autor:
Milos Petrovic, Inmaculada M. González-González, James P. Clement, Silvia Viana da Silva, Christophe Mulle, Ladislav Vyklicky, Jeremy M. Henley
Publikováno v:
Petrovic, M, Silva, S V D, Clement, J P, Vyklicky, L, Mulle, C, Gonzalez, M I & Henley, J M 2017, ' Metabotropic action of postsynaptic kainate receptors triggers hippocampal long-term potentiation ', Nature Neuroscience, vol. 20, no. 4, pp. 529–539 . https://doi.org/10.1038/nn.4505
Long-term potentiation (LTP) in the rat hippocampus is the most extensively studied cellular model for learning and memory. Induction of classical LTP involves an NMDA-receptor- and calcium-dependent increase in functional synaptic AMPA receptors, me
Publikováno v:
Traffic (Copenhagen, Denmark)
Traffic
Traffic
Kainate receptors (KARs) play fundamentally important roles in controlling synaptic function and regulating neuronal excitability. Postsynaptic KARs contribute to excitatory neurotransmission but the molecular mechanisms underlying their activity-dep
Publikováno v:
Petrovic, M, Gonzalez-Gonzalez, M I & Henley, J M 2016, ' Editorial : Ionotropic Glutamate Receptors Trafficking in Health and Disease ', Frontiers in Cellular Neuroscience, vol. 10, 242 . https://doi.org/10.3389/fncel.2016.00242
[no abstract]
Autor:
Filip A. Konopacki, Nadia Jaafari, Daniel L. Rocca, Andrew J Doherty, Inmaculada M. González-González, Jeremy M. Henley, Kevin A. Wilkinson
Publikováno v:
Wiley Interdisciplinary Reviews: Membrane Transport and Signaling. 1:31-44
Kainate receptors (KARs) are ligand-gated ion channels that can regulate neuronal network activity and are involved in processes ranging from neuronal development and differentiation to neurodegeneration and neuronal cell death. They are tetrameric a
Publikováno v:
Journal of Neurochemistry. 110:264-274
The glutamate transporter GLT1 is expressed in at least two isoforms, GLT1a and GLT1b, which differ in their C termini. As GLT1 is an oligomeric protein, we have investigated whether GLT1a and GLT1b might associate as hetero-oligomers. Differential t
Publikováno v:
Glia. 56:963-974
The activity of the main glutamate transporter in the CNS, GLT1, can be regulated by protein kinase C (PKC). It is known that activation of PKC by phorbol esters promotes the clathrin-dependent internalization of the transporter, followed by its lyso
Autor:
Francisco Zafra, Noemí García-Tardón, Cecilio Giménez, Beatriz Cubelos, Inmaculada M. González-González
Publikováno v:
Journal of Neurochemistry. 105:1834-1848
The glutamate transporter (GLT1) regulates glutamate concentrations in glutamatergic synapses and it is expressed in at least two isoforms, GLT1a and GLT1b. In this work, we show that the C-terminus of GLT1b is able to interact with the PDZ domains o
Publikováno v:
Neuroscience. 153:95-107
Sodium-coupled neutral amino-acid transporter member 2 (SNAT2) belongs to the family of neutral amino-acid transporters. SNAT2 is encoded by the gene Slc38a2, whose expression was reported to increase in vitro in fibroblasts, endothelial and renal ce
Publikováno v:
Journal of Neurochemistry. 95:1047-1058
Recent evidence indicates that the glycine transporter-1 (GLYT1) plays a role in regulation of NMDA receptor function through tight control of glycine concentration in its surrounding medium. Immunohistochemical studies have demonstrated that, as wel