Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Inmaculada Lopez‐Sanchez"'
Autor:
Lingxia Qiao, Saptarshi Sinha, Amer Ali Abd El‐Hafeez, I‐Chung Lo, Krishna K Midde, Tony Ngo, Nicolas Aznar, Inmaculada Lopez‐Sanchez, Vijay Gupta, Marilyn G Farquhar, Padmini Rangamani, Pradipta Ghosh
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 4, Pp 1-27 (2023)
Abstract Cancers represent complex autonomous systems, displaying self‐sufficiency in growth signaling. Autonomous growth is fueled by a cancer cell's ability to “secrete‐and‐sense” growth factors (GFs): a poorly understood phenomenon. Usin
Externí odkaz:
https://doaj.org/article/fa7b3bde97544f3e97560e5c2c0d0fc4
Autor:
Sequoyah Reynoso, Vanessa Castillo, Gajanan Dattatray Katkar, Inmaculada Lopez-Sanchez, Sahar Taheri, Celia Espinoza, Cristina Rohena, Debashis Sahoo, Pascal Gagneux, Pradipta Ghosh
Publikováno v:
eLife, Vol 10 (2021)
For a sperm to successfully fertilize an egg, it must first undergo capacitation in the female reproductive tract and later undergo acrosomal reaction (AR) upon encountering an egg surrounded by its vestment. How premature AR is avoided despite rapid
Externí odkaz:
https://doaj.org/article/5ebcf3910b234be9bef6d60f2c3ce120
Autor:
Cristina Rohena, Nicholas Kalogriopoulos, Navin Rajapakse, Suchismita Roy, Inmaculada Lopez-Sanchez, Jailal Ablack, Debashis Sahoo, Pradipta Ghosh
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101209- (2020)
Summary: Cells perceive and respond to the extracellular matrix via integrin receptors; their dysregulation has been implicated in inflammation and cancer metastasis. Here we show that a guanine nucleotide-exchange modulator of trimeric-GTPase Gαi,
Externí odkaz:
https://doaj.org/article/c57ce9a32f9c42038e557eee1549c154
Autor:
Nicolas Aznar, Krishna K Midde, Ying Dunkel, Inmaculada Lopez-Sanchez, Yelena Pavlova, Arthur Marivin, Jorge Barbazán, Fiona Murray, Ulrich Nitsche, Klaus-Peter Janssen, Karl Willert, Ajay Goel, Miguel Abal, Mikel Garcia-Marcos, Pradipta Ghosh
Publikováno v:
eLife, Vol 4 (2015)
Wnt signaling is essential for tissue homeostasis and its dysregulation causes cancer. Wnt ligands trigger signaling by activating Frizzled receptors (FZDRs), which belong to the G-protein coupled receptor superfamily. However, the mechanisms of G pr
Externí odkaz:
https://doaj.org/article/af5395b5b53c4d27b63c1bcee1f12367
Autor:
Inmaculada Lopez-Sanchez, Sahar Taheri, Vanessa Castillo, Pradipta Ghosh, Gajanan D. Katkar, Cristina C. Rohena, Sequoyah Reynoso, Pascal Gagneux, Debashis Sahoo, Celia R. Espinoza
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
SUMMARYFor a sperm to successfully fertilize an egg, it must first undergo capacitation in the female reproductive tract, and later undergo acrosomal reaction (AR) upon encountering an egg surrounded by its vestment. How premature AR is avoided despi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83984c797b018d5f9256ef5afa243a0c
https://escholarship.org/uc/item/042675h3
https://escholarship.org/uc/item/042675h3
Autor:
Cristina C. Rohena, Inmaculada Lopez-Sanchez, Vanessa Castillo, Pradipta Ghosh, Gajanan D. Katkar, Sahar Taheri, Debashis Sahoo, Sequoyah Reynoso, Celia R. Espinoza, Pascal Gagneux
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b20d1a4724f216ec16ddb225ce35d75
https://doi.org/10.7554/elife.69160.sa2
https://doi.org/10.7554/elife.69160.sa2
Autor:
Krishna Midde, I-Chung Lo, Pradipta Ghosh, Inmaculada Lopez-Sanchez, Saptarshi Sinha, Tony Ngo, Amer Ali Abd El-Hafeez, Vijay Gupta, Padmini Rangamani, Nicolas Aznar, Marilyn G. Farquhar, Lingxia Qiao
Cancers represent complex autonomous systems, displaying self-sufficiency in growth signaling. Autonomous growth is fueled by a cancer cell’s ability to ‘secrete-and-sense’ growth factors: a poorly understood phenomenon. Using an integrated sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f2cb155359294917a4e9bd25b2a6e2f
https://doi.org/10.1101/2021.03.18.436048
https://doi.org/10.1101/2021.03.18.436048
Autor:
Pradipta Ghosh, Mikel Garcia-Marcos, Inmaculada Lopez-Sanchez, Majid Ghassemian, Krishna Midde, Nicolas Aznar, Tony Ngo, Suchismita Roy, Changsheng Lin, Nicholas A. Kalogriopoulos, Fiona Murray, Irina Kufareva
Publikováno v:
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 46
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2020, 117 (46), pp.28763-28774. ⟨10.1073/pnas.2004699117⟩
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 46
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2020, 117 (46), pp.28763-28774. ⟨10.1073/pnas.2004699117⟩
The molecular mechanisms by which receptor tyrosine kinases (RTKs) and heterotrimeric G proteins, two major signaling hubs in eukaryotes, independently relay signals across the plasma membrane have been extensively characterized. How these hubs cross
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb50308f6771f69deb3765543f3c247
https://europepmc.org/articles/PMC7682395/
https://europepmc.org/articles/PMC7682395/
Autor:
Inmaculada Lopez-Sanchez, Navin Rajapakse, Debashis Sahoo, Nicholas A. Kalogriopoulos, Jailal N. G. Ablack, Cristina C. Rohena, Suchismita Roy, Pradipta Ghosh
Publikováno v:
iScience, vol 23, iss 6
iScience, Vol 23, Iss 6, Pp 101209-(2020)
iScience
iScience, Vol 23, Iss 6, Pp 101209-(2020)
iScience
Summary Cells perceive and respond to the extracellular matrix via integrin receptors; their dysregulation has been implicated in inflammation and cancer metastasis. Here we show that a guanine nucleotide-exchange modulator of trimeric-GTPase Gαi, G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3023ac749efeb1566afc8a4d09f94ecc
https://escholarship.org/uc/item/6222w6f2
https://escholarship.org/uc/item/6222w6f2
Autor:
Nina N. Sun, Pradipta Ghosh, Jason Ear, Irina Kufareva, Fang He, Inmaculada Lopez-Sanchez, Ying Dunkel, Majid Ghassemian, Nicolas Aznar, Kendall Satterfield, Debashis Sahoo
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67239ce4b5757c0cd6eb9d1a208b9d72
https://doi.org/10.1096/fasebj.2018.32.1_supplement.533.37
https://doi.org/10.1096/fasebj.2018.32.1_supplement.533.37