Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Inmaculada Ibánez de Cáceres"'
Autor:
Rocío Rosas-Alonso, Julian Colmenarejo-Fernández, Olga Pernía, Miranda Burdiel, Carlos Rodríguez-Antolín, Itsaso Losantos-García, Tania Rubio, Rocío Moreno-Velasco, Isabel Esteban-Rodríguez, Virginia Martínez-Marín, Paloma Yubero, Nicolas Costa-Fraga, Angel Díaz-Lagares, Rafael López-López, Eva Díaz-Martin, Juan F. García, Catalina Vivancos Sánchez, Maria Luisa Gandía-González, Gema Moreno-Bueno, Javier de Castro, Inmaculada Ibánez de Cáceres
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Glioblastoma (GB) is a devastating tumor of the central nervous system characterized by a poor prognosis. One of the best-established predictive biomarker in IDH-wildtype GB is O6-methylguanine-DNA methyltransferase (MGMT) methylation (mMGMT
Externí odkaz:
https://doaj.org/article/e4a8484a046145d48a70e38e2c8d1575
Autor:
Miranda Burdiel, Julia Jiménez, Carlos Rodríguez-Antolín, Álvaro García-Guede, Olga Pernía, Ana Sastre-Perona, Rocío Rosas-Alonso, Julián Colmenarejo, Carmen Rodríguez-Jiménez, María Dolores Diestro, Virginia Martínez-Marín, Oliver Higueras, Patricia Cruz, Itsaso Losantos-García, Héctor Peinado, Olga Vera, Javier de Castro, Inmaculada Ibáñez de Cáceres
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-5 (2023)
Abstract Small extracellular vesicles (sEVs) in the blood of cancer patients contain higher amounts of tumor markers than those identified as free-circulating. miRNAs have significant biomedical relevance due to their high stability and feasible dete
Externí odkaz:
https://doaj.org/article/fb3fd8538ff04f0a980527d02e7153c5
Autor:
Jonathan Foox, Jessica Nordlund, Claudia Lalancette, Ting Gong, Michelle Lacey, Samantha Lent, Bradley W. Langhorst, V. K. Chaithanya Ponnaluri, Louise Williams, Karthik Ramaswamy Padmanabhan, Raymond Cavalcante, Anders Lundmark, Daniel Butler, Christopher Mozsary, Justin Gurvitch, John M. Greally, Masako Suzuki, Mark Menor, Masaki Nasu, Alicia Alonso, Caroline Sheridan, Andreas Scherer, Stephen Bruinsma, Gosia Golda, Agata Muszynska, Paweł P. Łabaj, Matthew A. Campbell, Frank Wos, Amanda Raine, Ulrika Liljedahl, Tomas Axelsson, Charles Wang, Zhong Chen, Zhaowei Yang, Jing Li, Xiaopeng Yang, Hongwei Wang, Ari Melnick, Shang Guo, Alexander Blume, Vedran Franke, Inmaculada Ibanez de Caceres, Carlos Rodriguez-Antolin, Rocio Rosas, Justin Wade Davis, Jennifer Ishii, Dalila B. Megherbi, Wenming Xiao, Will Liao, Joshua Xu, Huixiao Hong, Baitang Ning, Weida Tong, Altuna Akalin, Yunliang Wang, Youping Deng, Christopher E. Mason
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-30 (2021)
Abstract Background Cytosine modifications in DNA such as 5-methylcytosine (5mC) underlie a broad range of developmental processes, maintain cellular lineage specification, and can define or stratify types of cancer and other diseases. However, the w
Externí odkaz:
https://doaj.org/article/8a322eba1d2e4d2ca87ac4166dc473a4
Autor:
Darío Sanchez-Cabrero, Álvaro Garcia-Guede, Miranda Burdiel, Olga Pernía, Julián Colmenarejo-Fernandez, Laura Gutierrez, Oliver Higuera, Isabel Esteban Rodriguez, Rocío Rosas-Alonso, Carlos Rodriguez-Antolín, Itsaso Losantos-García, Olga Vera, Javier De Castro-Carpeño, Inmaculada Ibanez de Caceres
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11464 (2023)
Despite advances in non-small cell lung cancer (NSCLC) research, this is still the most common cancer type that has been diagnosed up to date. microRNAs have emerged as useful clinical biomarkers in both tissue and liquid biopsy. However, there are n
Externí odkaz:
https://doaj.org/article/c82e7bcbdbe64a4e99943c7310982c98
Autor:
Javier Guijarro-Eguinoa, Sara Arjona-Hernandez, Stefan Stewart, Olga Pernia, Pedro Arias, Itsaso Losantos-García, Tania Rubio, Miranda Burdiel, Carlos Rodriguez-Antolin, Patricia Cruz-Castellanos, Oliver Higuera, Alberto M. Borobia, Sonia Rodriguez-Novoa, Javier de Castro-Carpeño, Inmaculada Ibanez de Caceres, Rocio Rosas-Alonso
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 9843 (2023)
Platin-based chemotherapy is the standard treatment for patients with non-small cell lung cancer (NSCLC). However, resistance to this therapy is a major obstacle in successful treatment. In this study, we aimed to investigate the impact of several ph
Externí odkaz:
https://doaj.org/article/0e5fbe9e69d44576a788296407aa5978
Autor:
Carlos Rodríguez-Antolín, Laura Felguera-Selas, Olga Pernía, Olga Vera, Isabel Esteban, Itsaso Losantos García, Javier de Castro, Rocío Rosas-Alonso, Inmaculada Ibanez de Caceres
Publikováno v:
Cell & Bioscience, Vol 9, Iss 1, Pp 1-6 (2019)
Abstract Non-small-cell lung cancer (NSCLC) is the most common malignancy worldwide. Platinum-based chemotherapy is the standard of care for these patients. Recent research showed that miR-7 methylation status is a biomarker of cisplatin resistance i
Externí odkaz:
https://doaj.org/article/1f94d0872e2e4bb9a3639f57237c1d58
Autor:
Jonathan Foox, Jessica Nordlund, Claudia Lalancette, Ting Gong, Michelle Lacey, Samantha Lent, Bradley W. Langhorst, V. K. Chaithanya Ponnaluri, Louise Williams, Karthik Ramaswamy Padmanabhan, Raymond Cavalcante, Anders Lundmark, Daniel Butler, Christopher Mozsary, Justin Gurvitch, John M. Greally, Masako Suzuki, Mark Menor, Masaki Nasu, Alicia Alonso, Caroline Sheridan, Andreas Scherer, Stephen Bruinsma, Gosia Golda, Agata Muszynska, Paweł P. Łabaj, Matthew A. Campbell, Frank Wos, Amanda Raine, Ulrika Liljedahl, Tomas Axelsson, Charles Wang, Zhong Chen, Zhaowei Yang, Jing Li, Xiaopeng Yang, Hongwei Wang, Ari Melnick, Shang Guo, Alexander Blume, Vedran Franke, Inmaculada Ibanez de Caceres, Carlos Rodriguez-Antolin, Rocio Rosas, Justin Wade Davis, Jennifer Ishii, Dalila B. Megherbi, Wenming Xiao, Will Liao, Joshua Xu, Huixiao Hong, Baitang Ning, Weida Tong, Altuna Akalin, Yunliang Wang, Youping Deng, Christopher E. Mason
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/10f42b1e364944e7840858cc9d08d7ba
Autor:
Luis Augusto Aguirre, Karla Montalbán-Hernández, José Avendaño-Ortiz, Elvira Marín, Roberto Lozano, Víctor Toledano, Laura Sánchez-Maroto, Verónica Terrón, Jaime Valentín, Elisa Pulido, José Carlos Casalvilla, Carolina Rubio, Luke Diekhorst, Fernando Laso-García, Carlos del Fresno, Ana Collazo-Lorduy, Beatriz Jiménez-Munarriz, Paloma Gómez-Campelo, Emilio Llanos-González, María Fernández-Velasco, Carlos Rodríguez-Antolín, Rebeca Pérez de Diego, Ramón Cantero-Cid, Enrique Hernádez-Jimenez, Enrique Álvarez, Rocío Rosas, Blanca dies López-Ayllón, Javier de Castro, Stefanie K. Wculek, Carolina Cubillos-Zapata, Inmaculada Ibáñez de Cáceres, Prudencio Díaz-Agero, María Gutiérrez Fernández, María Paz de Miguel, David Sancho, Leon Schulte, Rosario Perona, Cristóbal Belda-Iniesta, Lisardo Boscá, Eduardo López-Collazo
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
The ‘cancer cell fusion’ theory is controversial due to the lack of methods available to identify hybrid cells and to follow the phenomenon in patients. However, it seems to be one of the best explanations for both the origin and metastasis of pr
Externí odkaz:
https://doaj.org/article/40902723f587442ab7098a6e4d03fc9a
Autor:
Olga Vera, Carlos Rodriguez-Antolin, Javier de Castro, Florian A. Karreth, Thomas A. Sellers, Inmaculada Ibanez de Caceres
Publikováno v:
Epigenetics, Vol 13, Iss 3, Pp 251-263 (2018)
Long noncoding RNAs (lncRNAs) are critical regulators of cell biology whose alteration can lead to the development of diseases such as cancer. The potential role of lncRNAs and their epigenetic regulation in response to platinum treatment are largely
Externí odkaz:
https://doaj.org/article/79286a7c152844f991a32afb7a09ab07
Autor:
Verónica Moncho-Amor, Laura Pintado-Berninches, Inmaculada Ibañez de Cáceres, Ester Martín-Villar, Miguel Quintanilla, Probir Chakravarty, María Cortes-Sempere, Beatriz Fernández-Varas, Carlos Rodriguez-Antolín, Javier de Castro, Leandro Sastre, Rosario Perona
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 8, p 2036 (2019)
DUSP6/MKP3 is a dual-specific phosphatase that regulates extracellular regulated kinase ERK1/2 and ERK5 activity, with an increasingly recognized role as tumor suppressor. In silico studies from Gene expression Omnibus (GEO) and Cancer Genome atlas (
Externí odkaz:
https://doaj.org/article/fb059b0d7aee46c3a97b652aa3ff1004