Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Inmaculada Cuchillo-Ibañez"'
Autor:
Matthew Paul Lennol, Irene Sánchez-Domínguez, Inmaculada Cuchillo-Ibañez, Elena Camporesi, Gunnar Brinkmalm, Daniel Alcolea, Juan Fortea, Alberto Lleó, Guadalupe Soria, Fernando Aguado, Henrik Zetterberg, Kaj Blennow, Javier Sáez-Valero
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-19 (2022)
Abstract Objective The purpose of this study was to examine the levels of cerebrospinal fluid (CSF) apolipoprotein E (apoE) species in Alzheimer’s disease (AD) patients. Methods We analyzed two CSF cohorts of AD and control individuals expressing d
Externí odkaz:
https://doaj.org/article/41418a77e345433d8fa1f79989c326a6
Autor:
Inmaculada Cuchillo-Ibañez, Matthew P. Lennol, Sergio Escamilla, Trinidad Mata-Balaguer, Lucía Valverde-Vozmediano, Inmaculada Lopez-Font, Isidro Ferrer, Javier Sáez-Valero
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-17 (2021)
Abstract Background Members of the low-density lipoprotein (LDL) receptor family are involved in endocytosis and in transducing signals, but also in amyloid precursor protein (APP) processing and β-amyloid secretion. ApoER2/LRP8 is a member of this
Externí odkaz:
https://doaj.org/article/0d07f7ff82b34f70b1698695455e552b
Amyloid precursor protein glycosylation is altered in the brain of patients with Alzheimer’s disease
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-15 (2020)
Abstract Background The amyloid precursor protein (APP) is a transmembrane glycoprotein that undergoes alternative proteolytic processing. Its processing through the amyloidogenic pathway originates a large sAPPβ ectodomain fragment and the β-amylo
Externí odkaz:
https://doaj.org/article/49bcb95c76ef4a888d389d3e36b4826e
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
Externí odkaz:
https://doaj.org/article/748c9c158cc443de9822d28153d5144f
Autor:
Oscar Ramirez-Molina, Tiare Silva-Grecchi, Jessica Panes-Fernández, Daniela Mennickent, Jorge Fuentealba, Inmaculada Cuchillo-Ibañez, Javier Sáez-Valero, Patricio A. Castro, Pamela A. Godoy
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Biomedicine & Pharmacotherapy, Vol 142, Iss, Pp 111968-(2021)
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Biomedicine & Pharmacotherapy, Vol 142, Iss, Pp 111968-(2021)
Amyloid beta peptide (Aβ) is tightly associated with the physiopathology of Alzheimer’s Disease (AD) as one of the most important factors in the evolution of the pathology. In this context, we previously reported that Aβ increases the expression
Autor:
Trinidad Mata-Balaguer, Sergio Escamilla, Javier Sáez-Valero, Inmaculada Cuchillo-Ibañez, Inmaculada B. Lopez-Font, Isidro Ferrer, Matthew P. Lennol
Background. Members of the low-density lipoprotein (LDL) receptor family are involved in endocytosis and in transducing signals, but also in APP (amyloid precursor protein) processing and β-amyloid secretion. ApoER2/LRP8 is a member of this family w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07b3f1bc38cee1075774aff975db30cc
https://doi.org/10.21203/rs.3.rs-220026/v1
https://doi.org/10.21203/rs.3.rs-220026/v1
Autor:
Inmaculada Lopez-Font, Javier Sáez-Valero, Inmaculada Cuchillo-Ibañez, Guillermo Iborra-Lazaro, José-Luis Molinuevo, Raquel Sánchez-Valle
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Reelin is a glycoprotein associated with synaptic plasticity and neurotransmission. The malfunctioning of reelin signaling in the brain is likely to contribute to the pathogenesis of Alzheimer's disease (AD). Reelin binding to Apolipoprotein E recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5658941eb036d5e1229a432c94053bc0
http://hdl.handle.net/10261/217765
http://hdl.handle.net/10261/217765
Autor:
Valeria Balmaceda, Trinidad Mata-Balaguer, Inmaculada Lopez-Font, Javier Sáez-Valero, Inmaculada Cuchillo-Ibañez
Publikováno v:
Journal of Alzheimer's Disease. 52:403-416
In the continuing search for proteins that play a role in Alzheimer's disease (AD) and that are related to the pathological hallmarks, those that influence cognitive function and that constitute potential therapeutic targets deserve special interest.
Autor:
Isidro Ferrer, Inmaculada Cuchillo-Ibañez, Miguel Calero, Javier Sáez-Valero, Trinidad Mata-Balaguer
Increasing evidence indicates that altered reelin signaling could contribute to synaptic dysfunction in Alzheimer's disease (AD). We found that reelin protein and mRNA levels were increased in the AD brain (particularly at advanced Braak stages in ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd3843bc83f4d7da9cd6ca7e7bf002b8
http://hdl.handle.net/10261/296234
http://hdl.handle.net/10261/296234