Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Inmaculada C. Sorribes"'
Autor:
Marc D. Ryser, Diego Mallo, Allison Hall, Timothy Hardman, Lorraine M. King, Sergei Tatishchev, Inmaculada C. Sorribes, Carlo C. Maley, Jeffrey R. Marks, E. Shelley Hwang, Darryl Shibata
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Invasion is a critical step in tumor development. Here, in colorectal cancer, the authors show that multiclonal invasion of the muscularis mucosae is pervasive, suggesting that invasive capacity is not a significant bottleneck in the evolution of the
Externí odkaz:
https://doaj.org/article/0d25956044414a47b376fdedd27dfad9
Publikováno v:
Computational and Systems Oncology, Vol 1, Iss 2, Pp n/a-n/a (2021)
Abstract The use of prostate‐specific antigen (PSA) as a prognostic indicator for prostate cancer (PCa) patients is controversial, especially since it has been shown to correlate poorly with tumor burden. The poor quality of PSA as a biomarker coul
Externí odkaz:
https://doaj.org/article/3f9ba1777ff849c39efcb2b7523a4869
Autor:
Harsh Vardhan Jain, Inmaculada C. Sorribes, Samuel K. Handelman, Johnna Barnaby, Trachette L. Jackson
Publikováno v:
Cancers, Vol 13, Iss 8, p 1872 (2021)
Sipuleucel-T (Provenge) is the first live cell vaccine approved for advanced, hormonally refractive prostate cancer. However, survival benefit is modest and the optimal combination or schedule of sipuleucel-T with androgen depletion remains unknown.
Externí odkaz:
https://doaj.org/article/4301e8e265fe428a97bca3fc2dea75f5
Autor:
Inmaculada C. Sorribes, Marc D. Ryser, Timothy Hardman, E. Shelley Hwang, Carlo C. Maley, Lorraine M. King, Darryl Shibata, Jeffrey R. Marks, Allison Hall, Sergei Tatishchev, Diego Mallo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Nature Communications
Intra-tumoral heterogeneity (ITH) could represent clonal evolution where subclones with greater fitness confer more malignant phenotypes and invasion constitutes an evolutionary bottleneck. Alternatively, ITH could represent branching evolution with
Publikováno v:
Computational and Systems Oncology, Vol 1, Iss 2, Pp n/a-n/a (2021)
The use of prostate‐specific antigen (PSA) as a prognostic indicator for prostate cancer (PCa) patients is controversial, especially since it has been shown to correlate poorly with tumor burden. The poor quality of PSA as a biomarker could be expl
Autor:
Allison Hall, Marc D. Ryser, E. Shelley Hwang, Darryl Shibata, Lorraine M. King, Inmaculada C. Sorribes, Timothy Hardman, Diego Mallo, Carlo C. Maley, Jeffrey R. Marks
Intra-tumoral heterogeneity (ITH) could represent clonal evolution where subclones with greater fitness confer more malignant phenotypes and invasion constitutes an evolutionary bottleneck. Alternatively, ITH could represent branching evolution with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276d46a0b08374e2143035b423bdec84
https://doi.org/10.1101/842203
https://doi.org/10.1101/842203
Autor:
Inmaculada C. Sorribes, B. Manley, R. Stephens, Jakob Nikolas Kather, A. Basu, Maximilian A.R. Strobl, N. Vitos, P. M. Enriquez-Navas, Cliona O'Farrelly, H. Enderling, Xu Feng, Iman Tavassoly, R. Brady, D. Lemanne, Niveditha Nerlakanti
Renal cell carcinoma (RCC) is one of the ten most common and lethal cancers in the United States. Tumor heterogeneity and development of resistance to treatment suggest that patient-specific evolutionary therapies may hold the key to better patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10cdc9d72c70355722e515d3cae76ab
https://doi.org/10.1101/563130
https://doi.org/10.1101/563130
Publikováno v:
Biophysical journal. 116(8)
Brain tumor growth and tumor-induced edema result in increased intracranial pressure (ICP), which, in turn, is responsible for conditions as benign as headaches and vomiting, or as severe as seizures, neurological damage, or even death. Therefore, it
Autor:
Timothy Hardman, Lunden A Simpson, Marc D. Ryser, Allison Hall, E. Shelley Hwang, Jeffrey R. Marks, Carlo C. Maley, Darryl Shibata, Diego Mallo, Inmaculada C. Sorribes, Lorraine M. King, Ethan Wu, Matthew Greenwald
Publikováno v:
Cancer Research. 80:PR02-PR02
Introduction. The natural history of preinvasive breast cancer, or ductal carcinoma in situ (DCIS) remains poorly understood. Overcoming this gap would allow risk-appropriate treatment for patients diagnosed with DCIS. We used a multiregional sequenc
Autor:
Lunden A Simpson, Allison Hall, Darryl Shibata, E. Shelley Hwang, Carlo C. Maley, Lorraine M. King, Inmaculada C. Sorribes, Jeffrey R. Marks, Timothy Hardman, Diego Mallo, Marc D. Ryser, Matthew Greenwald
Publikováno v:
Cancer Research. 80:2683-2683
Introduction. Ductal carcinoma in situ (DCIS) of the breast has a limited propensity to progress to invasive breast cancer. However, due to a lack of markers that predict the risk of progression to invasive cancer, many DCIS patients may receive unne