Clinical response to linaclotide at week 4 predicts sustained response in irritable bowel syndrome with constipation and improvements in digestive and extra-digestive symptoms

Autor: Blanca Serrano-Falcón, Sílvia Delgado-Aros, Fermín Mearin, Constanza Ciriza de los Ríos, Jordi Serra, Miguel Mínguez, Miguel Montoro Huguet, Antonia Perelló, Cecilio Santander, Ángeles Pérez Aisa, Inmaculada Bañón-Rodríguez, Enrique Rey

Publikováno v: Therapeutic Advances in Gastroenterology, Vol 12 (2019)

Background: Linaclotide is approved for the treatment of moderate-to-severe irritable bowel syndrome (IBS) with constipation (IBS-C) in adults. This study aimed to assess factors predictive of a clinical response and improvements in non-IBS symptoms

Externí odkaz: https://doaj.org/article/50aafbf1ceab4e1c9ec2b632cf36f5b7

Clinical response to linaclotide at week 4 predicts sustained response in irritable bowel syndrome with constipation and improvements in digestive and extra-digestive symptoms

Autor: Miguel Montoro Huguet, Fermín Mearin, Cecilio Santander, Silvia Delgado-Aros, Miguel Minguez, Inmaculada Bañón-Rodríguez, Enrique Rey, Jordi Serra, Constanza Ciriza de los Ríos, Blanca Serrano-Falcón, Antonia Perelló, Angeles Perez Aisa

Publikováno v: Therapeutic Advances in Gastroenterology, Vol 12 (2019)
Therapeutic Advances in Gastroenterology
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
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r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA

Background:Linaclotide is approved for the treatment of moderate-to-severe irritable bowel syndrome (IBS) with constipation (IBS-C) in adults. This study aimed to assess factors predictive of a clinical response and improvements in non-IBS symptoms w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4861fa5164be6d512c3969ae26054e4
https://doaj.org/article/50aafbf1ceab4e1c9ec2b632cf36f5b7

Synaptotagmin-Like Proteins Control Formation of a Single Apical Membrane Domain in Epithelial Cells

Autor: Mitsunori Fukuda, David M. Bryant, Natalie Spivak, Ilenia Bernascone, Keith E. Mostov, Alejo E. Rodriguez-Fraticelli, Christiaan L. Slim, Fernando Martín-Belmonte, Anirban Datta, Takao Yasuda, Inmaculada Bañón-Rodríguez, Kitty Young, Silvia Vergarajauregui, Paul Brakeman, Manuel Gálvez-Santisteban

Publikováno v: Nature cell biology

The formation of epithelial tissues requires both the generation of apical-basal polarity and the coordination of this polarity between neighbouring cells to form a central lumen. During de novo lumen formation, vectorial membrane transport contribut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c46c0efafeb6220c787bfe4a6173f79
http://europepmc.org/articles/PMC3433678

Role of WASP in cell polarity and podosome dynamics of myeloid cells

Autor: Inés M. Antón, Inmaculada Bañón-Rodríguez, Yolanda Calle, Hsiu-Chuan Chou, James Monypenny, Gareth E. Jones, Adrian J. Thrasher

Publikováno v: European Journal of Cell Biology
Monypenny, J, Chou, H-C, Banon-Rodriguez, I, Thrasher, A J, Anton, I M, Jones, G E & Calle, Y 2011, ' Role of WASP in cell polarity and podosome dynamics of myeloid cells ', European Journal of Cell Biology, vol. 90, no. 2-3, pp. 198-204 . https://doi.org/10.1016/j.ejcb.2010.05.009

The integrin-dependent migration of myeloid cells requires tight coordination between actin-based cell membrane protrusion and integrin-mediated adhesion to form a stable leading edge. Under this mode of migration, polarised myeloid cells including d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18289de8b639e140d7575a7681950939
https://doi.org/10.1016/j.ejcb.2010.05.009

Semaphorin-Plexin Signaling Controls Mitotic Spindle Orientation during Epithelial Morphogenesis and Repair

Autor: Atsushi Kumanogoh, Tianliang Sun, Fernando Martín-Belmonte, Timo Franz, Cord Brakebusch, Jakub M. Swiercz, Ivana Matković, Hermann Josef Gröne, Jingjing Xia, Inmaculada Bañón-Rodríguez, Giuseppina Federico, Roland H. Friedel, Stefan Offermanns, Thomas Worzfeld

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

© 2015 Elsevier Inc. Morphogenesis, homeostasis, and regeneration of epithelial tissues rely on the accurate orientation of cell divisions, which is specified by the mitotic spindle axis. To remain in the epithelial plane, symmetrically dividing epi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ca420cfcbe743345469f62dd559d6e
http://hdl.handle.net/10261/140492