Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Inmaculada, Posadas"'
Publikováno v:
Pharmacological Research, Vol 201, Iss , Pp 107102- (2024)
Since its discovery in 1998, the use of small interfering RNA (siRNA) has been increasing in biomedical studies because of its ability to very selectively inhibit the expression of any target gene. Thus, siRNAs can be used to generate therapeutic com
Externí odkaz:
https://doaj.org/article/4bb6c28c7ace4b75851938fcd182365b
Autor:
Cristina de la Torre, Pablo Játiva, Inmaculada Posadas, Darío Manzanares, José L. Jiménez Blanco, Carmen Ortiz Mellet, José Manuel García Fernández, Valentín Ceña
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2424 (2022)
Synthetic double-stranded small interfering RNAs (siRNAs) mimic interference RNAs (RNAi) and can bind target mRNAs with a high degree of specificity, leading to selective knockdown of the proteins they encode. However, siRNAs are very labile and must
Externí odkaz:
https://doaj.org/article/e1323517ef9e4ff0a4c10937bad41467
Publikováno v:
INTED2023 Proceedings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2326916f8cab7883fab513b2635e5eb1
https://doi.org/10.21125/inted.2023.0598
https://doi.org/10.21125/inted.2023.0598
Autor:
Joaquín González Fuentes, Jorge Laborda, Pilar Clemente-Casares, María Victoria Lozano, Consuelo Ripoll, Cristina García, María Del Mar Arroyo-Jiménez, Noemí Villaseca-González, Trinidad Argente, Lucía Castro-Vázquez, Ana Sousa, Almudena Ruiz, Joaquín Calixto García, Maria Del Rocío Fernández-Santos, María Francisca Galindo, Elena Domínguez, Diego Herrera, Diana Capilla, Inmaculada Posadas, María Dolores Pérez-Carrión, Jorge Selva, Manuel Jesús Santander-Ortega, Cristina Martín
Publikováno v:
INTED2023 Proceedings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9629e314cc5fe166301ba0bf98662362
https://doi.org/10.21125/inted.2023.2133
https://doi.org/10.21125/inted.2023.2133
Autor:
Laura Gallego-Yerga, Inmaculada Posadas, Cristina de la Torre, Jesús Ruiz-Almansa, Francesco Sansone, Carmen Ortiz Mellet, Alessandro Casnati, José M. García Fernández, Valentín Ceña
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Giant amphiphiles encompassing a hydrophilic β-cyclodextrin (βCD) component and a hydrophobic calix[4]arene (CA4) module undergo self-assembly in aqueous media to afford core-shell nanospheres or nanocapsules, depending on the nanoprecipitation pro
Externí odkaz:
https://doaj.org/article/10552c482df643388ad61375e402dc7e
Poly(Cyclohexene Phthalate) Nanoparticles for Controlled Dasatinib Delivery in Breast Cancer Therapy
Autor:
Enrique Niza, Cristina Nieto-Jiménez, María del Mar Noblejas-López, Iván Bravo, José Antonio Castro-Osma, Felipe de la Cruz-Martínez, Marc Martínez de Sarasa Buchaca, Inmaculada Posadas, Jesús Canales-Vázquez, Agustín Lara-Sanchez, Daniel Hermida-Merino, Eduardo Solano, Alberto Ocaña, Carlos Alonso-Moreno
Publikováno v:
Nanomaterials, Vol 9, Iss 9, p 1208 (2019)
The effect on the activity in breast cancer models of the small tyrosine kinase inhibitor dasatinib (DAS), either alone or in combination with other antitumoral agents, has been recently explored. However, DAS is characterized by its low and highly p
Externí odkaz:
https://doaj.org/article/77bce3454e644773aeaf008901cc437f
Autor:
Jolanta Janiszewska, Inmaculada Posadas, Pablo Játiva, Marta Bugaj-Zarebska, Zofia Urbanczyk-Lipkowska, Valentín Ceña
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165704 (2016)
Glioblastomas are the most common malignant primary brain tumours in adults and one of the most aggressive and difficult-to-treat cancers. No effective treatment exits actually for this tumour and new therapeutic approaches are needed for this diseas
Externí odkaz:
https://doaj.org/article/2a929ae6d22c47168c68b64652b58afa
Autor:
Inmaculada Posadas, Laura Romero-Castillo, Rosa-Anna Ronca, Andrii Karpus, Serge Mignani, Jean-Pierre Majoral, Mariángeles Muñoz-Fernández, Valentín Ceña
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 8; Pages: 4391
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (8), pp.4391. ⟨10.3390/ijms23084391⟩
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (8), pp.4391. ⟨10.3390/ijms23084391⟩
International audience; Nanoparticles are playing an increasing role in biomedical applications. Excitotoxicity plays a significant role in the pathophysiology of neurodegenerative diseases, such as Alzheimer’s or Parkinson’s disease. Glutamate i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98f0ee2122cc055d0330ef7b1c63116a
https://pubmed.ncbi.nlm.nih.gov/35457211
https://pubmed.ncbi.nlm.nih.gov/35457211
Publikováno v:
Processes. 11:319
Neurodegenerative diseases (NDs), such as Parkinson’s Disease (PD), Alzheimer’s Disease (AD), Multiple Sclerosis (MS) and amyotrophic lateral sclerosis (ALS), are characterized by progressive loss of structure or function of neurons. Current ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fac74cf85eb25cac2065c27fb81b6002
https://doi.org/10.3390/pr11020319
https://doi.org/10.3390/pr11020319
Autor:
Inmaculada Posadas, María Pérez
Publikováno v:
EDULEARN Proceedings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dacec17713702b2830af19cb037627b0
https://doi.org/10.21125/edulearn.2021.0847
https://doi.org/10.21125/edulearn.2021.0847