Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Inken M Beck"'
Autor:
Petr Kasparek, Zuzana Ileninova, Olga Zbodakova, Ivan Kanchev, Oldrich Benada, Karel Chalupsky, Maria Brattsand, Inken M Beck, Radislav Sedlacek
Publikováno v:
PLoS Genetics, Vol 13, Iss 1, p e1006566 (2017)
Netherton syndrome (NS) is a severe skin disease caused by the loss of protease inhibitor LEKTI, which leads to the dysregulation of epidermal proteases and severe skin-barrier defects. KLK5 was proposed as a major protease in NS pathology, however i
Externí odkaz:
https://doaj.org/article/bd44d971be1a4155b195a02dcfec4518
Autor:
Inken M Beck, René Rückert, Katja Brandt, Markus S Mueller, Thorsten Sadowski, Rena Brauer, Peter Schirmacher, Rolf Mentlein, Radislav Sedlacek
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2343 (2008)
Matrix metalloproteinase-19 (MMP19) affects cell proliferation, adhesion, and migration in vitro but its physiological role in vivo is poorly understood. To determine the function of MMP19, we generated mice deficient for MMP19 by disrupting the cata
Externí odkaz:
https://doaj.org/article/941b05dcaf7f4328b83f0a2cc37a3bf8
Autor:
Ivana Bukova, Katarzyna Izabela Szczerkowska, Michaela Prochazkova, Inken M. Beck, Jan Prochazka, Radislav Sedlacek
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
WIZ (Widely Interspaced Zinc Finger) is associated with the G9a-GLP protein complex, a key H3K9 methyltransferase suggesting a role in transcriptional repression. However, its role in embryonic development is poorly described. In order to assess the
Externí odkaz:
https://doaj.org/article/cf311487e87e48b8b2855482f96f3e19
Autor:
Katarzyna Izabela Szczerkowska, Ivana Bukova, Michaela Prochazkova, Jan Prochazka, Inken M. Beck, Radislav Sedlacek
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
WIZ (Widely Interspaced Zinc Finger) is associated with the G9a-GLP protein complex, a key H3K9 methyltransferase suggesting a role in transcriptional repression. However, its role in embryonic development is poorly described. In order to assess the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d9ecaf311e1132c69a2691b5905441
https://www.frontiersin.org/articles/10.3389/fcell.2021.620692/full
https://www.frontiersin.org/articles/10.3389/fcell.2021.620692/full
Reporter gene mouse lines are routinely used for studies related to functional genomics, proteomics, cell biology or cell-based drug screenings, and represent a crucial platform for in vivo research. In the generation of knock-in reporter lines, new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1df1abb339e080de2406de08fd9741
https://doi.org/10.1016/j.dnarep.2020.102936
https://doi.org/10.1016/j.dnarep.2020.102936
Autor:
Peter J. Makovicky, Jiri Lindovsky, Jianguo Zhang, Jan Prochazka, Mingming Shi, Jan Dvorak, Chongyi Jiang, Radislav Sedlacek, Agnieszka Kubik-Zahorodna, Xiao Liu, Silvia Petrezsélyová, Mingyan Fang, Vendula Novosadova, Inken M. Beck, Katarzyna Izabela Szczerkowska, Marcela Palkova, Lingyan Chen, Bjoern Schuster
Publikováno v:
Cell & Bioscience, Vol 9, Iss 1, Pp 1-10 (2019)
Cell & Bioscience
Cell & Bioscience
Zinc finger 644 (Zfp644 in mouse, ZNF644 in human) gene is a transcription factor whose mutation S672G is considered a potential genetic factor of inherited high myopia. ZNF644 interacts with G9a/GLP complex, which functions as a H3K9 methyltransfera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d301d51f7b21f54cddf10b1854f37d0a
https://www.repository.cam.ac.uk/handle/1810/302710
https://www.repository.cam.ac.uk/handle/1810/302710
Autor:
Inken M. Beck, Zuzana Červinková, Josef Houstek, Radislav Sedlacek, Katerina Tauchmannova, Jana Kovalčíková, Otto Kucera, Hana Nuskova, Marek Vrbacky, Tomáš Mráček
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1859:e92-e93
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d6c0e9521a69cddb5aa1ab03998c739
https://doi.org/10.1016/j.bbabio.2018.09.274
https://doi.org/10.1016/j.bbabio.2018.09.274
Autor:
Marian Hajduch, Radislav Sedlacek, Olga Zbodakova, K.-H. Herzig, Vladimir Korinek, Jolana Tureckova, Rena Brauer, M. Khoylou, Karel Chalupsky, Jozef Skarda, T. Karhu, Ivan Kanchev, Frantisek Spoutil, Petr Kasparek, Inken M. Beck, Martin Gregor, Jan Prochazka
Publikováno v:
Mucosal immunology. 9(4)
Matrix metalloproteinases (MMPs) are potential biomarkers for disease activity in inflammatory bowel disease (IBD). However, clinical trials targeting MMPs have not succeeded, likely due to poor understanding of the biological functions of individual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab01f4dbb3774dd33b88d80e816dc3ab
https://pubmed.ncbi.nlm.nih.gov/26555704
https://pubmed.ncbi.nlm.nih.gov/26555704
Autor:
Radislav Sedlacek, Inken M. Beck
Publikováno v:
Transgenic research. 24(1)
The 12th Transgenic Technology meeting was held in Edinburgh on 6th–8th October 2014 and interest to participate in the meeting overcame all expectations. The TT2014 was the largest meeting ever with more than 540 scientists, technicians, and stude
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c605326baf51c1411baf430f82e4f710
https://pubmed.ncbi.nlm.nih.gov/25477276
https://pubmed.ncbi.nlm.nih.gov/25477276
Autor:
Karel Chalupsky, Inken M. Beck, Radislav Sedlacek, Zuzana Ileninova, Ivan Kanchev, Olga Zbodakova, Oldrich Benada, Maria Brattsand, Petr Kasparek
Publikováno v:
PLoS Genetics, Vol 13, Iss 1, p e1006566 (2017)
PLoS Genetics
PLoS Genetics
Netherton syndrome (NS) is a severe skin disease caused by the loss of protease inhibitor LEKTI, which leads to the dysregulation of epidermal proteases and severe skin-barrier defects. KLK5 was proposed as a major protease in NS pathology, however i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df2b8804f878e4c4899f20a96247b09
https://doi.org/10.1371/journal.pgen.1006566
https://doi.org/10.1371/journal.pgen.1006566