Identification of metabolic pathways essential for fitness of Salmonella Typhimurium in vivo.

Autor: Lotte Jelsbak, Hassan Hartman, Casper Schroll, Jesper T Rosenkrantz, Sebastien Lemire, Inke Wallrodt, Line E Thomsen, Mark Poolman, Mogens Kilstrup, Peter R Jensen, John E Olsen

Publikováno v: PLoS ONE, Vol 9, Iss 7, p e101869 (2014)

Bacterial infections remain a threat to human and animal health worldwide, and there is an urgent need to find novel targets for intervention. In the current study we used a computer model of the metabolic network of Salmonella enterica serovar Typhi

Externí odkaz: https://doaj.org/article/2f9d27ba633c4d1ab9d6e9fabe836462

Polyamines are required for virulence in Salmonella enterica serovar Typhimurium.

Autor: Lotte Jelsbak, Line Elnif Thomsen, Inke Wallrodt, Peter Ruhdal Jensen, John Elmerdahl Olsen

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e36149 (2012)

Sensing and responding to environmental cues is a fundamental characteristic of bacterial physiology and virulence. Here we identify polyamines as novel environmental signals essential for virulence of Salmonella enterica serovar Typhimurium, a major

Externí odkaz: https://doaj.org/article/85bc1855eb6c4cde8501403a2418b390

Identification of Metabolic Pathways Essential for Fitness of Salmonella Typhimurium In Vivo

Autor: Mogens Kilstrup, Jesper T. Rosenkrantz, Line Elnif Thomsen, Casper Schroll, Sebastien Lemire, Hassan B. Hartman, Peter Ruhdal Jensen, Mark G. Poolman, Lotte Jelsbak, Inke Wallrodt, John Elmerdahl Olsen

Publikováno v: PLoS ONE
PLoS ONE, Vol 9, Iss 7, p e101869 (2014)
Jelsbak, L, Hartman, H, Schroll, C, Rosenkrantz, J T, Lemire, S, Wallrodt, I, Thomsen, L E, Poolman, M, Kilstrup, M, Jensen, P R & Olsen, J E 2014, ' Identification of Metabolic Pathways Essential for Fitness of Salmonella Typhimurium In Vivo ', P L o S One, vol. 9, no. 7, e101869 . https://doi.org/10.1371/journal.pone.0101869

Bacterial infections remain a threat to human and animal health worldwide, and there is an urgent need to find novel targets for intervention. In the current study we used a computer model of the metabolic network of Salmonella enterica serovar Typhi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22d698b4d28bd7add639b1daa265226
http://europepmc.org/articles/PMC4081726

The putative thiosulfate sulfurtransferases PspE and GlpE contribute to virulence of Salmonella Typhimurium in the mouse model of systemic disease

Autor: Line Elnif Thomsen, Inke Wallrodt, Sebastien Lemire, Lotte Jelsbak, Lotte Thorndahl, John Elmerdahl Olsen

Publikováno v: Wallrodt, I, Jelsbak, L, Thorndahl, L, Thomsen, L E, Lemire, S & Olsen, J E 2013, ' The putative thiosulfate sulfurtransferases PspE and GlpE contribute to virulence of Salmonella Typhimurium in the mouse model of systemic disease. ', P L o S One, vol. 8, no. 8, e70829 . https://doi.org/10.1371/journal.pone.0070829
PLoS ONE
Wallrodt, I, Jelsbak, L, Thorndahl, L, Thomsen, L E, Lemire, S & Olsen, J E 2013, ' The putative thiosulfate sulfurtransferases PspE and GlpE contribute to virulence of Salmonella Typhimurium in the mouse model of systemic disease. ', PLOS ONE, vol. 8, no. 8, e70829 . https://doi.org/10.1371/journal.pone.0070829
PLoS ONE, Vol 8, Iss 8, p e70829 (2013)

The phage-shock protein PspE and GlpE of the glycerol 3-phosphate regulon of Salmonella enterica serovar Typhimurium are predicted to belong to the class of thiosulfate sulfurtransferases, enzymes that traffic sulfur between molecules. In the present

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb1c7d2b2ef3119dc960d79e106fa20
https://curis.ku.dk/portal/da/publications/the-putative-thiosulfate-sulfurtransferases-pspe-and-glpe-contribute-to-virulence-of-salmonella-typhimurium-in-the-mouse-model-of-systemic-disease(8ba28dd1-3747-4ff8-be55-f1df9e13ce17).html