Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Inke R. Koenig"'
Autor:
Andreas Boehle, MD, PhD, Dorothea Zywietz, Irina Robrahn-Nitschke, MD, Inke R. Koenig, MD, PhD, Achim Lusch, MD, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 8, Iss 2, Pp 101112- (2023)
Purpose: The aim of this study was to compare a surgical with a Phoenix-derived definition of cure at 4 years after treatment by 125J low-dose-rate brachytherapy (LDR-BT) in patients with low- and intermediate-risk prostate cancer. Methods and Materi
Externí odkaz:
https://doaj.org/article/f5d9e1cb0f48414da21111f21e248ae6
Autor:
Christine Klein, Fabiola Del Greco M, Christina M. Lill, Inke R. Koenig, Sandeep Grover, Meike Kasten
ObjectiveDopaminergic neurotransmission is known to be a potential modulator of risky behaviors including substance abuse, promiscuity, and gambling. Furthermore, observational studies have shown associations between risky behaviors and Parkinson’s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac0f75ac7210d1556712a76ba9b6e0a
https://doi.org/10.1101/446807
https://doi.org/10.1101/446807
Autor:
Adnan Kastrati, Wu Yin, Jeanette Erdmann, Ruth J. F. Loos, Paul L. Auer, Susanne Moebus, Christina Willenborg, Piera Angelica Merlini, Jochen Kruppa, Anubha Mahajan, Julian C. van Capelleveen, Christa Meisinger, Charles Kooperberg, Natalie R. van Zuydam, Domenico Girelli, Erik P A Van Iperen, Rebecca D. Jackson, Tom R. Webb, Dan M. Roden, Ursula M. Schick, Colin N. A. Palmer, Eli A. Stahl, Mark I. McCarthy, Andres Metspalu, David-Alexandre Trégouët, Markus Perola, Kathleen Stirrups, G. Kees Hovingh, Martina Mueller-Nurasyid, Maris Alver, Christopher Newton-Cheh, Daniel J. Rader, Karl-Heinz Joeckel, Karen O. Akinsanya, Nilesh J. Samani, Alistair S. Hall, Stefano Duga, Louise A. Donnelly, J. Wouter Jukema, Nour Eddine El-Mokhtari, Rosanna Asselta, Tibor V. Varga, Heribert Schunkert, Erwin P. Bottinger, Paola G. Ferrario, Nathan O. Stitziel, Nicola Marziliano, Marie-Pierre Dubé, Andre Franke, Robert A. Scott, Thomas Meitinger, Stavroula Kanoni, Jan-Håkan Jansson, Christian Hengstenberg, Svati H. Shah, Josh C. Denny, Melanie Waldenberger, Alex S. F. Doney, Nicola Martinelli, Cristen J. Willer, Olle Melander, Hugh Watkins, He Zhang, Inke R. Koenig, Ron Do, Thomas F. Vogt, Chunyu Liu, Omri Gottesman, Kari Kuulasmaa, Peter S. Braund, Praveen Surendran, Dermot F. Reilly, Per Hoffmann, Georg Ehret, Karl L. Laugwitz, Diego Ardissino, Børge G. Nordestgaard, Joanna M. M. Howson, Raimund Erbel, Stefan A. Escher, Wolfgang Lieb, Hong-Hee Won, Majid Nikpay, Martin Farrall, Stefanie Heilmann, Ruth McPherson, Nicholas G. D. Masca, Evelin Mihailov, Danish Saleheen, Andrew D. Morris, Neil R. Robertson, Oddgeir L. Holmen, Sekar Kathiresan, Annette Peters, Jean-Claude Tardif, Alaa AlQarawi, Frank Kee, Jennifer Kriebel, Panos Deloukas, Anuj Goel, Kristian Hveem, Konstantin Strauch, Alexander P. Reiner, Paul W. Franks, John R. Thompson, Robin Young, William E. Kraus, Nicholas J. Wareham, Aldi T. Kraja, Rajiv Chowdhury, Oliviero Olivieri, Folkert W. Asselbergs, Adam S. Butterworth, Daniel I. Chasman, Gina M. Peloso, Peter Weeke, Christian M. Shaffer, Naveed Sattar, Muredach P. Reilly, John Danesh, Marco M Ferrario, Ian Ford, Lingyao Zeng, Marju Orho-Melander, Louis-Philippe Lemieux Perreault, Tõnu Esko, Eirini Marouli, Thorsten Kessler, Yingchang Lu
Publikováno v:
New England Journal of Medicine, Vol. 374, No 12 (2016) pp. 1134-1144
New England journal of medicine, 374(12), 1134-1144. Massachussetts Medical Society
New England Journal of Medicine
New England Journal of Medicine, 374(12), 1134. Massachussetts Medical Society
N. Engl. J. Med. 374, 1134-1144 (2016)
New England journal of medicine, 374(12), 1134-1144. Massachussetts Medical Society
New England Journal of Medicine
New England Journal of Medicine, 374(12), 1134. Massachussetts Medical Society
N. Engl. J. Med. 374, 1134-1144 (2016)
BACKGROUND: \ud \ud The discovery of low-frequency coding variants affecting the risk of coronary artery disease has facilitated the identification of therapeutic targets.\ud \ud METHODS: \ud \ud Through DNA genotyping, we tested 54,003 coding-sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70819d577ccccdda3d4ec9e71321723d
https://archive-ouverte.unige.ch/unige:127757
https://archive-ouverte.unige.ch/unige:127757
Autor:
Richard N. Bergman, Markku S. Nieminen, Peter Vollenweider, André G. Uitterlinden, Luigi Ferrucci, Iris M. Heid, Lynda M. Rose, Brenda W.J.H. Penninx, Nicholas G. Martin, Joshua C. Bis, Aaron Isaacs, Jaspal S. Kooner, Gavin Lucas, Caroline Hayward, Masahiro Koseki, Andrew A. Hicks, Maja Barbalić, Marju Orho-Melander, Xueling Sim, James Scott, Manjinder S. Sandhu, Damien C. Croteau-Chonka, Andreas Ziegler, Wilmar Igi, Igor Rudan, Aki S. Havulinna, Leslie A. Lange, Hilma Holm, James G. Wilson, Albert V. Smith, Chiara Sabatti, Candace Guiducci, Paul Elliott, A. Cecile J.W. Janssens, Dorret I. Boomsma, Harry Campbell, Lee M. Kaplan, Ruth J. F. Loos, Robert Luben, Veikko Salomaa, Kyunga Kim, James F. Wilson, Mark Seielstad, Ben A. Oostra, Robert Y.L. Zee, Talin Haritunians, Stacey Gabriel, Michael Boehnke, Ida Surakka, Alex N. Parker, Serena Sanna, Fabio Marroni, Leif Groop, Ingrid B. Borecki, Weihua Zhang, John R. Thompson, Paul M. Ridker, James P. Pirruccello, Nicole Soranzo, Ulf Gyllensten, G. Kees Hovingh, Jian'an Luan, Wendy L. McArdle, Alistair S. Hall, Yurii S. Aulchenko, Thomas Meitinger, John Whitfield, Gonçalo R. Abecasis, Yii-Der Ida Chen, Tien Yin Wong, Deborah A. Nickerson, Jaakko Tuomilehto, Kijoung Song, Reijo Laaksonen, Jeanette Erdmann, Daniel J. Rader, Jing Hua Zhao, Irene Pichler, Robert A. Hegele, Marjo-Riitta Järvelin, Guillaume Paré, Juha Sinisalo, Andrew C. Edmondson, Peter P. Pramstaller, E-Shyong Tai, Vilmundur Gudnason, Linda S. Adair, Min Jin Go, Heather M. Stringham, Nancy L. Pedersen, Bruce M. Psaty, Åsa Johansson, Guillaume Lettre, Tamara B. Harris, Christian Gieger, Toby Johnson, Cornelia M. van Duijn, Samuli Ripatti, Johannes H. Smit, Sigrid W. Fouchier, Gonneke Willemsen, Mark J. Rieder, Nicholas D. Hastie, Leena Peltonen, Jacqueline C. M. Witteman, David Schlessinger, Kiran Musunuru, Eric Boerwinkle, Kay-Tee Khaw, Massimo Mangino, Themistocles L. Assimes, Claudia Langenberg, Yoon Shin Cho, Elena Gonzalez, Eric J.G. Sijbrands, Toshiko Tanaka, Inês Barroso, Vincent Mooser, Eco J. C. de Geus, Karen L. Mohlke, Jaakko Kaprio, Eric E. Schadt, Gudmar Thorleifsson, Nelson B. Freimer, H.-Erich Wichmann, Francis S. Collins, Grant W. Montgomery, John J.P. Kastelein, Inke R. Koenig, Xiuqing Guo, Ruth McPherson, Benjamin F. Voight, Stefania Bandinelli, Sally L. Ricketts, S. Matthijs Boekholdt, Xin Yuan, David Altshuler, Marja-Liisa Lokki, Lori L. Bonnycastle, Aimo Ruokonen, Noël P. Burtt, Unnur Thorsteinsdottir, Markus Perola, Edward G. Lakatta, Serkalem Demissie, Kenechi Ejebe, Muredach P. Reilly, Florian Kronenberg, Panagiotis Deloukas, Gabriel Crawford, Lenore J. Launer, David P. Strachan, Xiaohui Li, Christian Hengstenberg, Olle Melander, Juha Saharinen, Ulf de Faire, Joshua D. Smith, Heribert Schunkert, Thomas Quertermous, Young Jin Kim, Alan R. Tall, Anna F. Dominiczak, Nicholas J. Wareham, Robert Roberts, Mark J. Caulfield, Tanya M. Teslovich, Daniel I. Chasman, Manuela Uda, Jong-Young Lee, Erik Ingelsson, Christopher W. Kuzawa, Jerome I. Rotter, Gina M. Peloso, Christie M. Ballantyne, Mingyao Li, Alan F. Wright, Albert Hofman, Angelo Scuteri, Rick Twee-Hee Ong, L. Adrienne Cupples, Taesung Park, Veronique Vitart, Kaisa Silander, Jouke-Jan Hottenga, Kari Stefansson, Christopher J. O'Donnell, Mary F. Feitosa, Tim D. Spector, Mark I. McCarthy, Nilesh J. Samani, Christopher T. Johansen, David Masson, Cristian Pattaro, Ioannis M. Stylianou, Angela Doering, Patricia B. Munroe, Herman A. Taylor, Patrik K. E. Magnusson, John C. Chambers, Claudia Lamina, Sekar Kathiresan, Dawn M. Waterworth, Jose M. Ordovas, Alan B. Feranil, Cristen J. Willer, Kirsten Ohm Kyvik, Gérard Waeber, Ronald M. Krauss
Publikováno v:
Teslovich, T M, Musunuru, K, Smith, A V, Edmondson, A C, Stylianou, I M, Willemsen, G, Uitterlinden, A G, Penninx, B W J H, Montgomery, GW, Martin, N G, Hottenga, J J, de Geus, E J C, Boomsma, D I, van Duijn, C M, Peltonen, L, Abecasis, G R, Boehnke, M & Kathiresan, S 2010, ' Biological, clinical and population relevance of 95 loci for blood lipids ', Nature, vol. 466, no. 7307, pp. 707-713 . https://doi.org/10.1038/nature09270
Teslovich, T M, Musunuru, K, Smith, A V, Edmondson, A C, Stylianou, I M, Koseki, M, Pirruccello, J P, Ripatti, S, Chasman, D I, Willer, C J, Johansen, C T, Fouchier, S W, Isaacs, A, Peloso, G M, Barbalic, M, Ricketts, S L, Bis, J C, Aulchenko, Y S, Thorleifsson, G, Feitosa, M F, Chambers, J, Orho-Melander, M, Melander, O, Johnson, T, Li, X, Guo, X, Li, M, Shin Cho, Y, Jin Go, M, Jin Kim, Y, Lee, J-Y, Park, T, Kim, K, Sim, X, Twee-Hee Ong, R, Croteau-Chonka, D C, Lange, L A, Smith, J D, Song, K, Hua Zhao, J, Yuan, X, Luan, J, Lamina, C, Ziegler, A, Zhang, W, Zee, R Y L, Wright, A F, Witteman, J C M, Wilson, J F, Willemsen, G, Wichmann, H-E, Whitfield, J B, Waterworth, D M, Wareham, N J, Waeber, G, Vollenweider, P, Voight, B F, Vitart, V, Uitterlinden, A G, Uda, M, Tuomilehto, J, Thompson, J R, Tanaka, T, Surakka, I, Stringham, H M, Spector, T D, Soranzo, N, Smit, J H, Sinisalo, J, Silander, K, Sijbrands, E J G, Scuteri, A, Scott, J, Schlessinger, D, Sanna, S, Salomaa, V, Saharinen, J, Sabatti, C, Ruokonen, A, Rudan, I, Rose, L M, Roberts, R, Rieder, M, Psaty, B M, Pramstaller, P P, Pichler, I, Perola, M, Penninx, B W J H, Pedersen, N L, Pattaro, C, Parker, A N, Pare, G, Oostra, B A, O'Donnell, C J, Nieminen, M S, Nickerson, D A, Montgomery, G W, Meitinger, T, McPherson, R, McCarthy, M I, McArdle, W, Masson, D, Martin, N G, Marroni, F, Mangino, M, Magnusson, P K E, Lucas, G, Luben, R, Loos, R J F, Lokki, M-L, Lettre, G, Langenberg, C, Launer, L J, Lakatta, E G, Laaksonen, R, Kyvik, K O, Kronenberg, F, König, I R, Khaw, K-T, Kaprio, J, Kaplan, L M, Johansson, A, Jarvelin, M-R, Janssens, A C J W, Ingelsson, E, Igl, W, Kees Hovingh, G, Hottenga, J-J, Hofman, A, Hicks, A A, Hengstenberg, C, Heid, I M, Hayward, C, Havulinna, A S, Hastie, N D, Harris, T B, Haritunians, T, Hall, A S, Gyllensten, U, Guiducci, C, Groop, L C, Gonzalez, E, Gieger, C, Freimer, N B, Ferrucci, L, Erdmann, J, Elliott, P, Ejebe, K G, Döring, A, Dominiczak, A F, Demissie, S, Deloukas, P, de Geus, E J C, de Faire, U, Crawford, G, Collins, F S, Chen, Y I, Caulfield, M J, Campbell, H, Burtt, N P, Bonnycastle, L L, Boomsma, D I, Boekholdt, S M, Bergman, R N, Barroso, I, Bandinelli, S, Ballantyne, C M, Assimes, T L, Quertermous, T, Altshuler, D, Seielstad, M, Wong, T Y, Tai, E-S, Feranil, A B, Kuzawa, C W, Adair, L S, Taylor, H A, Borecki, I B, Gabriel, S B, Wilson, J G, Holm, H, Thorsteinsdottir, U, Gudnason, V, Krauss, R M, Mohlke, K L, Ordovas, J M, Munroe, P B, Kooner, J S, Tall, A R, Hegele, R A, Kastelein, J J P, Schadt, E E, Rotter, J I, Boerwinkle, E, Strachan, D P, Mooser, V, Stefansson, K, Reilly, M P, Samani, N J, Schunkert, H, Cupples, L A, Sandhu, M S, Ridker, P M, Rader, D J, van Duijn, C M, Peltonen, L, Abecasis, G R, Boehnke, M & Kathiresan, S 2010, ' Biological, clinical and population relevance of 95 loci for blood lipids ', Nature, vol. 466, no. 7307, pp. 707-13 . https://doi.org/10.1038/nature09270
Nature, 466(7307), 707-713. Nature Publishing Group
Nature
Nature; Vol 466
Teslovich, T M, Musunuru, K, Smith, A V, Edmondson, A C, Stylianou, I M, Koseki, M, Pirruccello, J P, Ripatti, S, Chasman, D I, Willer, C J, Johansen, C T, Fouchier, S W, Isaacs, A, Peloso, G M, Barbalic, M, Ricketts, S L, Bis, J C, Aulchenko, Y S, Thorleifsson, G, Feitosa, M F, Chambers, J, Orho-Melander, M, Melander, O, Johnson, T, Li, X, Guo, X, Li, M, Cho, Y S, Go, M J, Kim, Y J, Lee, J-Y, Park, T, Kim, K, Sim, X, Ong, R T-H, Croteau-Chonka, D C, Lange, L A, Smith, J D, Song, K, Zhao, J H, Yuan, X, Luan, J, Lamina, C, Ziegler, A, Zhang, W, Zee, R Y L, Wright, A, Witteman, J C M, Wilson, J, Willemsen, G, Wichmann, H-E, Whitfield, J B, Waterworth, D M, Wareham, N J, Waeber, G, Vollenweider, P, Voight, B F, Vitart, V, Uitterlinden, A G, Uda, M, Tuomilehto, J, Thompson, J R, Tanaka, T, Surakka, I, Stringham, H M, Spector, T D, Soranzo, N, Smit, J H, Sinisalo, J, Silander, K, Sijbrands, E J G, Scuteri, A, Scott, J, Schlessinger, D, Sanna, S, Salomaa, V, Saharinen, J, Sabatti, C, Ruokonen, A, Rudan, I, Rose, L M, Roberts, R, Rieder, M, Psaty, B M, Pramstaller, P P, Pichler, I, Perola, M, Penninx, B W J H, Pedersen, N L, Pattaro, C, Parker, A N, Pare, G, Oostra, B A, O'Donnell, C J, Nieminen, M S, Nickerson, D A, Montgomery, G W, Meitinger, T, McPherson, R, McCarthy, M I, McArdle, W, Masson, D, Martin, N G, Marroni, F, Mangino, M, Magnusson, P K E, Lucas, G, Luben, R, Loos, R J F, Lokki, M-L, Lettre, G, Langenberg, C, Launer, L J, Lakatta, E G, Laaksonen, R, Kyvik, K O, Kronenberg, F, Koenig, I R, Khaw, K-T, Kaprio, J, Kaplan, L M, Johansson, A, Jarvelin, M-R, Janssens, A C J W, Ingelsson, E, Igi, W, Hovingh, G K, Hottenga, J-J, Hofman, A, Hicks, A A, Hengstenberg, C, Heid, I M, Hayward, C, Havulinna, A S, Hastie, N, Harris, T B, Haritunians, T, Hall, A S, Gyllensten, U, Guiducci, C, Groop, L C, Gonzalez, E, Gieger, C, Freimer, N B, Ferrucci, L, Erdmann, J, Elliott, P, Ejebe, K G, Doering, A, Dominiczak, A F, Demissie, S, Deloukas, P, de Geus, E J C, de Faire, U, Crawford, G, Collins, F S, Chen, Y I, Caulfield, M J, Campbell, H, Burtt, N P, Bonnycastle, L L, Boomsma, D I, Boekholdt, S M, Bergman, R N, Barroso, I, Bandinelli, S, Ballantyne, C M, Assimes, T L, Quertermous, T, Altshuler, D, Seielstad, M, Wong, T Y, Tai, E-S, Feranil, A B, Kuzawa, C W, Adair, L S, Taylor, H A, Borecki, I B, Gabriel, S B, Wilson, J G, Holm, H, Thorsteinsdottir, U, Gudnason, V, Krauss, R M, Mohlke, K L, Ordovas, J M, Munroe, P B, Kooner, J S, Tall, A R, Hegele, R A, Kastelein, J J P, Schadt, E E, Rotter, J I, Boerwinkle, E, Strachan, D P, Mooser, V, Stefansson, K, Reilly, M P, Samani, N J, Schunkert, H, Cupples, L A, Sandhu, M S, Ridker, P M, Rader, D J, van Duijn, C M, Peltonen, L, Abecasis, G R, Boehnke, M & Kathiresan, S 2010, ' Biological, clinical and population relevance of 95 loci for blood lipids ', Nature, vol. 466, no. 7307, pp. 707-713 . https://doi.org/10.1038/nature09270
Teslovich, T M, Musunuru, K, Smith, A V, Edmondson, A C, Stylianou, I M, Koseki, M, Pirruccello, J P, Ripatti, S, Chasman, D I, Willer, C J, Johansen, C T, Fouchier, S W, Isaacs, A, Peloso, G M, Barbalic, M, Ricketts, S L, Bis, J C, Aulchenko, Y S, Thorleifsson, G, Feitosa, M F, Chambers, J, Orho-Melander, M, Melander, O, Johnson, T, Li, X, Guo, X, Li, M, Shin Cho, Y, Jin Go, M, Jin Kim, Y, Lee, J-Y, Park, T, Kim, K, Sim, X, Twee-Hee Ong, R, Croteau-Chonka, D C, Lange, L A, Smith, J D, Song, K, Hua Zhao, J, Yuan, X, Luan, J, Lamina, C, Ziegler, A, Zhang, W, Zee, R Y L, Wright, A F, Witteman, J C M, Wilson, J F, Willemsen, G, Wichmann, H-E, Whitfield, J B, Waterworth, D M, Wareham, N J, Waeber, G, Vollenweider, P, Voight, B F, Vitart, V, Uitterlinden, A G, Uda, M, Tuomilehto, J, Thompson, J R, Tanaka, T, Surakka, I, Stringham, H M, Spector, T D, Soranzo, N, Smit, J H, Sinisalo, J, Silander, K, Sijbrands, E J G, Scuteri, A, Scott, J, Schlessinger, D, Sanna, S, Salomaa, V, Saharinen, J, Sabatti, C, Ruokonen, A, Rudan, I, Rose, L M, Roberts, R, Rieder, M, Psaty, B M, Pramstaller, P P, Pichler, I, Perola, M, Penninx, B W J H, Pedersen, N L, Pattaro, C, Parker, A N, Pare, G, Oostra, B A, O'Donnell, C J, Nieminen, M S, Nickerson, D A, Montgomery, G W, Meitinger, T, McPherson, R, McCarthy, M I, McArdle, W, Masson, D, Martin, N G, Marroni, F, Mangino, M, Magnusson, P K E, Lucas, G, Luben, R, Loos, R J F, Lokki, M-L, Lettre, G, Langenberg, C, Launer, L J, Lakatta, E G, Laaksonen, R, Kyvik, K O, Kronenberg, F, König, I R, Khaw, K-T, Kaprio, J, Kaplan, L M, Johansson, A, Jarvelin, M-R, Janssens, A C J W, Ingelsson, E, Igl, W, Kees Hovingh, G, Hottenga, J-J, Hofman, A, Hicks, A A, Hengstenberg, C, Heid, I M, Hayward, C, Havulinna, A S, Hastie, N D, Harris, T B, Haritunians, T, Hall, A S, Gyllensten, U, Guiducci, C, Groop, L C, Gonzalez, E, Gieger, C, Freimer, N B, Ferrucci, L, Erdmann, J, Elliott, P, Ejebe, K G, Döring, A, Dominiczak, A F, Demissie, S, Deloukas, P, de Geus, E J C, de Faire, U, Crawford, G, Collins, F S, Chen, Y I, Caulfield, M J, Campbell, H, Burtt, N P, Bonnycastle, L L, Boomsma, D I, Boekholdt, S M, Bergman, R N, Barroso, I, Bandinelli, S, Ballantyne, C M, Assimes, T L, Quertermous, T, Altshuler, D, Seielstad, M, Wong, T Y, Tai, E-S, Feranil, A B, Kuzawa, C W, Adair, L S, Taylor, H A, Borecki, I B, Gabriel, S B, Wilson, J G, Holm, H, Thorsteinsdottir, U, Gudnason, V, Krauss, R M, Mohlke, K L, Ordovas, J M, Munroe, P B, Kooner, J S, Tall, A R, Hegele, R A, Kastelein, J J P, Schadt, E E, Rotter, J I, Boerwinkle, E, Strachan, D P, Mooser, V, Stefansson, K, Reilly, M P, Samani, N J, Schunkert, H, Cupples, L A, Sandhu, M S, Ridker, P M, Rader, D J, van Duijn, C M, Peltonen, L, Abecasis, G R, Boehnke, M & Kathiresan, S 2010, ' Biological, clinical and population relevance of 95 loci for blood lipids ', Nature, vol. 466, no. 7307, pp. 707-13 . https://doi.org/10.1038/nature09270
Nature, 466(7307), 707-713. Nature Publishing Group
Nature
Nature; Vol 466
Teslovich, T M, Musunuru, K, Smith, A V, Edmondson, A C, Stylianou, I M, Koseki, M, Pirruccello, J P, Ripatti, S, Chasman, D I, Willer, C J, Johansen, C T, Fouchier, S W, Isaacs, A, Peloso, G M, Barbalic, M, Ricketts, S L, Bis, J C, Aulchenko, Y S, Thorleifsson, G, Feitosa, M F, Chambers, J, Orho-Melander, M, Melander, O, Johnson, T, Li, X, Guo, X, Li, M, Cho, Y S, Go, M J, Kim, Y J, Lee, J-Y, Park, T, Kim, K, Sim, X, Ong, R T-H, Croteau-Chonka, D C, Lange, L A, Smith, J D, Song, K, Zhao, J H, Yuan, X, Luan, J, Lamina, C, Ziegler, A, Zhang, W, Zee, R Y L, Wright, A, Witteman, J C M, Wilson, J, Willemsen, G, Wichmann, H-E, Whitfield, J B, Waterworth, D M, Wareham, N J, Waeber, G, Vollenweider, P, Voight, B F, Vitart, V, Uitterlinden, A G, Uda, M, Tuomilehto, J, Thompson, J R, Tanaka, T, Surakka, I, Stringham, H M, Spector, T D, Soranzo, N, Smit, J H, Sinisalo, J, Silander, K, Sijbrands, E J G, Scuteri, A, Scott, J, Schlessinger, D, Sanna, S, Salomaa, V, Saharinen, J, Sabatti, C, Ruokonen, A, Rudan, I, Rose, L M, Roberts, R, Rieder, M, Psaty, B M, Pramstaller, P P, Pichler, I, Perola, M, Penninx, B W J H, Pedersen, N L, Pattaro, C, Parker, A N, Pare, G, Oostra, B A, O'Donnell, C J, Nieminen, M S, Nickerson, D A, Montgomery, G W, Meitinger, T, McPherson, R, McCarthy, M I, McArdle, W, Masson, D, Martin, N G, Marroni, F, Mangino, M, Magnusson, P K E, Lucas, G, Luben, R, Loos, R J F, Lokki, M-L, Lettre, G, Langenberg, C, Launer, L J, Lakatta, E G, Laaksonen, R, Kyvik, K O, Kronenberg, F, Koenig, I R, Khaw, K-T, Kaprio, J, Kaplan, L M, Johansson, A, Jarvelin, M-R, Janssens, A C J W, Ingelsson, E, Igi, W, Hovingh, G K, Hottenga, J-J, Hofman, A, Hicks, A A, Hengstenberg, C, Heid, I M, Hayward, C, Havulinna, A S, Hastie, N, Harris, T B, Haritunians, T, Hall, A S, Gyllensten, U, Guiducci, C, Groop, L C, Gonzalez, E, Gieger, C, Freimer, N B, Ferrucci, L, Erdmann, J, Elliott, P, Ejebe, K G, Doering, A, Dominiczak, A F, Demissie, S, Deloukas, P, de Geus, E J C, de Faire, U, Crawford, G, Collins, F S, Chen, Y I, Caulfield, M J, Campbell, H, Burtt, N P, Bonnycastle, L L, Boomsma, D I, Boekholdt, S M, Bergman, R N, Barroso, I, Bandinelli, S, Ballantyne, C M, Assimes, T L, Quertermous, T, Altshuler, D, Seielstad, M, Wong, T Y, Tai, E-S, Feranil, A B, Kuzawa, C W, Adair, L S, Taylor, H A, Borecki, I B, Gabriel, S B, Wilson, J G, Holm, H, Thorsteinsdottir, U, Gudnason, V, Krauss, R M, Mohlke, K L, Ordovas, J M, Munroe, P B, Kooner, J S, Tall, A R, Hegele, R A, Kastelein, J J P, Schadt, E E, Rotter, J I, Boerwinkle, E, Strachan, D P, Mooser, V, Stefansson, K, Reilly, M P, Samani, N J, Schunkert, H, Cupples, L A, Sandhu, M S, Ridker, P M, Rader, D J, van Duijn, C M, Peltonen, L, Abecasis, G R, Boehnke, M & Kathiresan, S 2010, ' Biological, clinical and population relevance of 95 loci for blood lipids ', Nature, vol. 466, no. 7307, pp. 707-713 . https://doi.org/10.1038/nature09270
Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides are among the most important risk factors for coronary artery disease (CAD) and are targets for therapeutic interv
Autor:
Fredrik Karpe, Ivonne Jarick, Julius S. Ngwa, Alan F. Wright, Robert Luben, Aaron R. Folsom, Sailaja Vedantam, Veikko Salomaa, Markku J. Savolainen, Robert Clarke, Shah Ebrahim, Thomas A. Buchanan, Mao Fu, Albert Hofman, Philippe Goyette, Camilla H. Sandholt, Fabio Macciardi, Elizabeth K. Speliotes, Barbara McKnight, Anne McCarthy, Mika Kaehoenen, Christian Gieger, Jorma S. A. Viikari, Nicholas J. Timpson, Kirsti Kvaløy, Douglas F. Levinson, Toby Johnson, Cornelia M. van Duijn, Samuli Ripatti, Andrew A. Hicks, Niina Pellikka, Charles C. White, Leena Peltonen, Reedik Maegi, John-Olov Jansson, Qunyuan Zhang, Claudia Lamina, Robert C. Kaplan, Peter M. Visscher, Laura J. Scott, Claes Ohlsson, Brian Thomson, Jubao Duan, Heikki V. Huikuri, Stephen O'Rahilly, Anette P. Gjesing, David P. Strachan, Caroline S. Fox, Sekar Kathiresan, Anna-Liisa Hartikainen, Johannes Kettunen, Maris Teder-Laving, Erik Ingelsson, Mario A. Morken, Peter Kovacs, Elisabeth Widen, Caroline Hayward, Eleanor Wheeler, Jing Hua Zhao, Vilmundur Gudnason, Panos Deloukas, Jacqueline C. M. Witteman, Gert-Jan B. van Ommen, Eric Boerwinkle, Martin Wabitsch, Christian Hengstenberg, Beverley Balkau, Thor Aspelund, Neelam Hassanali, Paul M. Ridker, Nicole L. Glazer, Joyce B. J. van Meurs, Michel Marre, Alan James, Ben A. Oostra, David Meyre, Ida Surakka, Stefan Schreiber, Nigel W. Rayner, Heribert Schunkert, Thomas Quertermous, Stefan Gustafsson, Peter Kraft, Benjamin F. Voight, Irene Pichler, Olle Melander, Ozren Polasek, Antti Jula, Alan R. Sanders, Andrew R. Wood, Yoav Ben-Shlomo, Thomas Illig, Jianjun Liu, Gerard Waeber, André G. Uitterlinden, Torben Hansen, Helene Alavere, André Scherag, Paolo Manunta, Johannes Hebebrand, Themistocles L. Assimes, Stefan R. Bornstein, Jaakko Tuomilehto, Morris Brown, Jianfeng Xu, Yii-Der Ida Chen, Nancy L. Heard-Costa, Cristen J. Willer, Henrik Greonberg, Guillaume Lettre, John R. Thompson, Inês Barroso, John R. B. Perry, Andreas Ziegler, James F. Wilson, Christopher J. O'Donnell, Maurizio F. Facheris, Robert Lawrence, Jan Smit, Lyle J. Palmer, Ulf Gyllensten, Richard B. Hayes, Shengxu Li, Barbara Ludwig, Larry D. Atwood, Valgerdur Steinthorsdottir, Sabine Schipf, Jouko Saramies, Tanja Boes, Martin Ridderstråle, Jennie Hui, Lina Zgaga, Susann Scherag, Alexandra I. F. Blakemore, Marjolein Peters, Timo T. Valle, Nelson B. Freimer, Kay-Tee Khaw, Amy J. Swift, Michael Stumvoll, Miriam F. Moffatt, Cecilia M. Lindgren, Ayellet V. Segrè, Neil Robertson, Richard N. Bergman, Francis S. Collins, Ryan P. Welch, Mari-Liis Tammesoo, Devin Absher, Tamara B. Harris, Kari E. North, Manuela Uda, Karen L. Mohlke, Inga Prokopenko, Per Hall, Gudmar Thorleifsson, Marjo-Riitta Järvelin, Guillaume Paré, Stefan Gaget, G. Bragi Walters, Michael N. Weedon, Jean-Claude Tardif, Mary F. Feitosa, Anke Toenjes, Ken K. Ong, Cécile Lecoeur, Paavo Zitting, David S. Siscovick, Chih-Mei Chen, Peter Almgren, Anneli Pouta, Philippe Froguel, Pekka Jousilahti, Jaakko Kaprio, Maria Teresa Sciarrone Alibrandi, Sophie van Wingerden, Steven A. McCarroll, Oluf Pedersen, Shaun Purcell, Veronique Vitart, Leena Kinnunen, Markus Perola, Jacques S. Beckmann, Vincent Vatin, Christopher J. Groves, Zoltán Kutalik, Lu Qi, Volker Hoesel, Seppo Koskinen, Suzanne Rafelt, Anke Hinney, Annette Peters, David Schlessinger, Eero Kajantie, Jian Yang, Nicholas G. Martin, Joshua W. Knowles, Kristian Midthjell, Olivier Lantieri, Dorret I. Boomsma, Harry Campbell, Ulrich John, Kirsi H. Pietilaeinen, George Davey Smith, Carl G. P. Platou, Sarah H. Wild, Patricia B. Munroe, Iris M. Heid, Diana Marek, Michael Boehnke, Andres Metspalu, Hana Lango Allen, Peter Rzehak, Christine Cavalcanti-Proença, M. Carola Zillikens, Åsa Johansson, Anuj Goel, Andrew T. Hattersley, Massimo Mangino, Michael E. Goddard, Tim D. Spector, Winfried Rief, Jonathan Tyrer, Lachlan J. M. Coin, Peter P. Pramstaller, Narisu Narisu, John Beilby, Jonathan Stephens, Christina Barlassina, Pamela Fischer-Posovszky, Brenda W.J.H. Penninx, Kaisa Silander, Richard H. Myers, Jouke-Jan Hottenga, Eric E. Schadt, Francesco P. Cappuccio, Martin den Heijer, Fernando Rivadeneira, Lindsay L. Waite, Wilmar Igl, Igor Rudan, Manjinder S. Sandhu, Debbie A Lawlor, Kristian Hveem, Susanna Wiegand, Mari Nelis, Thomas Reinehr, Elisabeth Thiering, Inke R. Koenig, Stephan B. Felix, Fredrik Wiklund, Ian N. M. Day, Willem H. Ouwehand, Peter Schwarz, Richard M. Watanabe, Keri L. Monda, Kari Stefansson, Gudny Eiriksdottir, H-Erich Wichmann, Jianxin Shi, Najaf Amin, Carlos Iribarren, Heiko Krude, Dale R. Nyholt, Lenore J. Launer, Stephen J. Chanock, Harald Grallert, Hugh Watkins, Juergen Graessler, Tsegaselassie Workalemahu, Jeanette Erdmann, Mattias Lorentzon, Leif Groop, Teresa Ferreira, Chiara Lanzani, Johanna Kuusisto, Johan G. Eriksson, Tõnu Esko, Torben Jørgensen, Robert J. Weyant, Michael Preuss, Lambertus A. Kiemeney, Daniel I. Chasman, Daniel R. Witte, Kevin B. Jacobs, Nicole Soranzo, John M. C. Connell, Soumya Raychaudhuri, Jian'an Luan, Joshua C. Randall, Joachim Heinrich, Anthony J. Balmforth, Eva Fisher, Elizabeth S. Jewell, Alice M. Arnold, Nele Friedrich, Olli T. Raitakari, Henri Wallaschofski, Jeffrey R. O'Connell, Terho Lehtimaeki, Marika Kaakinen, Heather M. Stringham, Bo Isomaa, I. Sadaf Farooqi, Anna L. Dixon, Anne U. Jackson, Mark I. McCarthy, Lori L. Bonnycastle, Aila Rissanen, Joel N. Hirschhorn, Nilesh J. Samani, Aimo Ruokonen, Frank B. Hu, L. Adrienne Cupples, Amanda J. Bennett, Shamika Ketkar, Ruth J. F. Loos, Nicholas J. Wareham, Tiinamaija Tuomi, Timothy M. Frayling, Ulla Sovio, Georg Homuth, Liming Liang, Heiner Boeing, Unnur Thorsteinsdottir, Ingrid B. Borecki, Danielle M. Greenawalt, Rosanda Mulić, Ivana Kolcic, Talin Haritunians, Mark J. Caulfield, Marja-Liisa Lokki, Tanya M. Teslovich, Paul Elliott, Matt Neville, Nilanjan Chatterjee, Albert V. Smith, Andrew P. Morris, Fabio Busonero, Gonçalo R. Abecasis, Jaana Laitinen, Michael R. Erdos, Candace Guiducci, Lee M. Kaplan, Aki S. Havulinna, Pablo V. Gejman, Alan R. Shuldiner, Serena Sanna, David J. Hunter, Sonja I. Berndt, Carla I. G. Vogel, Alistair S. Hall, Karol Estrada, Sven Bergmann, Thomas Meitinger, Gonneke Willemsen, Andrew C. Heath, Katja K.H. Aben, Markku Laakso, Juha Sinisalo, Tuomas O. Kilpelaenen, Mark E. Cooper, Heike Biebermann, Eco J. C. de Geus, Grant W. Montgomery, Sophie Visvikis-Siest, Thomas W. Winkler, Ju-Hyun Park, Alex N. Parker, Peter S. Chines, James Nemesh, Nabila Bouatia-Naji, Wendy L. McArdle, Roberto Elosua, Markku S. Nieminen
Publikováno v:
Nature Genetics, 42(11), 937
Speliotes, E K, Willer, C J, Berndt, S I, Monda, K L, Thorleifson, G, Jackson, A U, Lango Allen, H, Lindgren, C M, Luan, J, Mägi, R, Hottenga, J J, de Geus, E J C, Martin, N G, Willemsen, G, Boomsma, D I, Penninx, B W J H, Uitterlinden, A G, Zillikens, M C, Visscher, P M, Peltonen, L, van Duijn, C M, Thorsteinsdottir, U, Abecasis, G R, Barroso, I, Boehnke, M, Stefansson, K, North, K E, McCarthy, M I, Hirschhorn, J N, Ingelsson, E & Loos, R J F 2010, ' Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index ', Nature Genetics, vol. 42, no. 11, pp. 937-948 . https://doi.org/10.1038/ng.686
Speliotes, E K, Willer, C J, Berndt, S I, Monda, K L, Thorleifsson, G, Jackson, A U, Lango Allen, H, Lindgren, C M, Luan, J, Mägi, R, Randall, J C, Vedantam, S, Winkler, T W, Qi, L, Workalemahu, T, Heid, I M, Steinthorsdottir, V, Stringham, H M, Weedon, M N, Wheeler, E, Wood, A R, Ferreira, T, Weyant, R J, Segrè, A V, Estrada, K, Liang, L, Nemesh, J, Park, J-H, Gustafsson, S, Kilpeläinen, T O, Yang, J, Bouatia-Naji, N, Esko, T, Feitosa, M F, Kutalik, Z, Mangino, M, Raychaudhuri, S, Scherag, A, Smith, A V, Welch, R, Zhao, J H, Aben, K K, Absher, D M, Amin, N, Dixon, A L, Fisher, E, Glazer, N L, Goddard, M E, Witte, D, Pedersen, O & MAGIC 2010, ' Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index ', Nature Genetics, vol. 42, no. 11, pp. 937-48 . https://doi.org/10.1038/ng.686
Nature genetics
Nature Genetics, 42(11), 937-948. Nature Publishing Group
Nature Genetics; Vol 42
Nature Genetics, 42(11), 937-U53. Nature Publishing Group
Nature Genetics
Nature Genetics, 42, 937-48
Nature genetics, vol. 42, no. 11, pp. 937-948
Speliotes, E K, Willer, C J, Berndt, S I, Monda, K L, Thorleifsson, G, Jackson, A U, Allen, H L, Lindgren, C M, Luan, J, Mägi, R, Randall, J C, Vedantam, S, Winkler, T W, Qi, L, Workalemahu, T, Heid, I M, Steinthorsdottir, V, Stringham, H M, Weedon, M N, Wheeler, E, Wood, A R, Ferreira, T, Weyant, R J, Segrè, A V, Estrada, K, Liang, L, Nemesh, J, Park, J-H, Gustafsson, S, Kilpeläinen, T O, Yang, J, Bouatia-Naji, N, Esko, T, Feitosa, M F, Kutalik, Z, Mangino, M, Raychaudhuri, S, Scherag, A, Smith, A V, Welch, R, Zhao, J H, Campbell, H, Hayward, C, Vitart, V, Wild, S H, Zgaga, L, Rudan, I, Wilson, J F & Wright, A F & Visscher, P M 2010, ' Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index ', Nature Genetics, vol. 42, no. 11, pp. 937-48 . https://doi.org/10.1038/ng.686
Nature Genetics, 42, 11, pp. 937-48
Speliotes, E K, Willer, C J, Berndt, S I, Monda, K L, Thorleifson, G, Jackson, A U, Lango Allen, H, Lindgren, C M, Luan, J, Mägi, R, Hottenga, J J, de Geus, E J C, Martin, N G, Willemsen, G, Boomsma, D I, Penninx, B W J H, Uitterlinden, A G, Zillikens, M C, Visscher, P M, Peltonen, L, van Duijn, C M, Thorsteinsdottir, U, Abecasis, G R, Barroso, I, Boehnke, M, Stefansson, K, North, K E, McCarthy, M I, Hirschhorn, J N, Ingelsson, E & Loos, R J F 2010, ' Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index ', Nature Genetics, vol. 42, no. 11, pp. 937-948 . https://doi.org/10.1038/ng.686
Speliotes, E K, Willer, C J, Berndt, S I, Monda, K L, Thorleifsson, G, Jackson, A U, Lango Allen, H, Lindgren, C M, Luan, J, Mägi, R, Randall, J C, Vedantam, S, Winkler, T W, Qi, L, Workalemahu, T, Heid, I M, Steinthorsdottir, V, Stringham, H M, Weedon, M N, Wheeler, E, Wood, A R, Ferreira, T, Weyant, R J, Segrè, A V, Estrada, K, Liang, L, Nemesh, J, Park, J-H, Gustafsson, S, Kilpeläinen, T O, Yang, J, Bouatia-Naji, N, Esko, T, Feitosa, M F, Kutalik, Z, Mangino, M, Raychaudhuri, S, Scherag, A, Smith, A V, Welch, R, Zhao, J H, Aben, K K, Absher, D M, Amin, N, Dixon, A L, Fisher, E, Glazer, N L, Goddard, M E, Witte, D, Pedersen, O & MAGIC 2010, ' Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index ', Nature Genetics, vol. 42, no. 11, pp. 937-48 . https://doi.org/10.1038/ng.686
Nature genetics
Nature Genetics, 42(11), 937-948. Nature Publishing Group
Nature Genetics; Vol 42
Nature Genetics, 42(11), 937-U53. Nature Publishing Group
Nature Genetics
Nature Genetics, 42, 937-48
Nature genetics, vol. 42, no. 11, pp. 937-948
Speliotes, E K, Willer, C J, Berndt, S I, Monda, K L, Thorleifsson, G, Jackson, A U, Allen, H L, Lindgren, C M, Luan, J, Mägi, R, Randall, J C, Vedantam, S, Winkler, T W, Qi, L, Workalemahu, T, Heid, I M, Steinthorsdottir, V, Stringham, H M, Weedon, M N, Wheeler, E, Wood, A R, Ferreira, T, Weyant, R J, Segrè, A V, Estrada, K, Liang, L, Nemesh, J, Park, J-H, Gustafsson, S, Kilpeläinen, T O, Yang, J, Bouatia-Naji, N, Esko, T, Feitosa, M F, Kutalik, Z, Mangino, M, Raychaudhuri, S, Scherag, A, Smith, A V, Welch, R, Zhao, J H, Campbell, H, Hayward, C, Vitart, V, Wild, S H, Zgaga, L, Rudan, I, Wilson, J F & Wright, A F & Visscher, P M 2010, ' Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index ', Nature Genetics, vol. 42, no. 11, pp. 937-48 . https://doi.org/10.1038/ng.686
Nature Genetics, 42, 11, pp. 937-48
Obesity is globaLy prevalent and highly heritable, but its underlying genetic factors remain largely elusive. To identify genetic loci for obesity susceptibility, we examined aSociations betwEn body maS index and ĝ̂1/42.8 miLion SNPs in up to 123,8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7dd940bce9e9209645e6816dc4e081
http://hdl.handle.net/1887/116783
http://hdl.handle.net/1887/116783
Autor:
Norbert Weissmann, Stephanie Wolff, Jochen Wilhelm, Rainer M. Bohle, Ludger Fink, Werner Seeger, Grazyna Kwapiszewska, Andreas Ziegler, Inke R Koenig, Isabel P. Laumanns
Publikováno v:
Respiratory Research, Vol 6, Iss 1, p 109 (2005)
Respiratory Research
Respiratory Research
Background Chronic hypoxia influences gene expression in the lung resulting in pulmonary hypertension and vascular remodelling. For specific investigation of the vascular compartment, laser-microdissection of intrapulmonary arteries was combined with