Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Inka Freise"'
Autor:
Jörn F. Ziegler, Chotima Böttcher, Marilena Letizia, Cansu Yerinde, Hao Wu, Inka Freise, Yasmina Rodriguez-Sillke, Ani K. Stoyanova, Martin E. Kreis, Patrick Asbach, Desiree Kunkel, Josef Priller, Ioannis Anagnostopoulos, Anja A. Kühl, Konstanze Miehle, Michael Stumvoll, Florian Tran, Broder Fredrich, Michael Forster, Andre Franke, Christian Bojarski, Rainer Glauben, Britt-Sabina Löscher, Britta Siegmund, Carl Weidinger
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The adipokine leptin modulates intestinal inflammation in mice. Here the authors describe a patient with inflammatory bowel disease and lipodystrophy, providing evidence that leptin aggravates intestinal inflammation with proinflammatory effects on l
Externí odkaz:
https://doaj.org/article/930d669ed7b944499b66502ad66aa5e6
Autor:
Cansu Yerinde, Jacqueline Keye, Sibel Durlanik, Inka Freise, Franziska Nowak, Hsiang-Jung Hsiao, Marilena Letizia, Stephan Schlickeiser, Benedikt Obermayer, Adrian Huck, Marie Friedrich, Hao Wu, Désirée Kunkel, Anja A. Kühl, Sebastian Bauer, Andreas Thiel, Britta Siegmund, Rainer Glauben, Carl Weidinger
Class II histone deacetylases (HDAC) orchestrate T cell-dependent immune responses via the epigenetic control of genes and via the post-translational modification of cytoplasmic and nuclear proteins. However, the contribution of single HDAC family me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bedc0e758b891e7d7ceb3a234ad488bd
https://doi.org/10.1101/2022.09.18.508452
https://doi.org/10.1101/2022.09.18.508452
Autor:
Rainer Glauben, Broder Fredrich, Anja A. Kühl, Josef Priller, Désirée Kunkel, Ioannis Anagnostopoulos, Andre Franke, Marilena Letizia, Inka Freise, Carl Weidinger, Florian Tran, Chotima Böttcher, Jörn F. Ziegler, Britt-Sabina Löscher, Patrick Asbach, Konstanze Miehle, Ani K. Stoyanova, Hao Wu, Christian Bojarski, Britta Siegmund, Martin E. Kreis, Michael Stumvoll, Cansu Yerinde, Yasmina Rodriguez-Sillke, Michael Forster
Publikováno v:
Nature Communications
Nature Communications 10(1), 5629 (2019). doi:10.1038/s41467-019-13559-7
Ziegler, J F, Böttcher, C, Letizia, M, Yerinde, C, Wu, H, Freise, I, Rodriguez-sillke, Y, Stoyanova, A K, Kreis, M E, Asbach, P, Kunkel, D, Priller, J, Anagnostopoulos, I, Kühl, A A, Miehle, K, Stumvoll, M, Tran, F, Fredrich, B, Forster, M, Franke, A, Bojarski, C, Glauben, R, Löscher, B, Siegmund, B & Weidinger, C 2019, ' Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn’s disease ', Nature Communications, vol. 10, no. 1 . https://doi.org/10.1038/s41467-019-13559-7
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications 10(1), 5629 (2019). doi:10.1038/s41467-019-13559-7
Ziegler, J F, Böttcher, C, Letizia, M, Yerinde, C, Wu, H, Freise, I, Rodriguez-sillke, Y, Stoyanova, A K, Kreis, M E, Asbach, P, Kunkel, D, Priller, J, Anagnostopoulos, I, Kühl, A A, Miehle, K, Stumvoll, M, Tran, F, Fredrich, B, Forster, M, Franke, A, Bojarski, C, Glauben, R, Löscher, B, Siegmund, B & Weidinger, C 2019, ' Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn’s disease ', Nature Communications, vol. 10, no. 1 . https://doi.org/10.1038/s41467-019-13559-7
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Leptin has been shown to modulate intestinal inflammation in mice. However, clinical evidence regarding its immune-stimulatory potential in human Crohn’s disease remains sparse. We here describe a patient with the unique combination of acquired gen
Autor:
Franziska Schmidt, Elena Sonnenberg, Rainer Glauben, D Lissner, Jochen Maul, Michael Schumann, Yasmina Rodriguez-Sillke, Britta Siegmund, Bosse Jessen, Andrey Kruglov, Inka Freise, Anja A. Kühl
Publikováno v:
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 19(4)
Background & Aims A substantial proportion patients with inflammatory bowel disease (IBD) have a primary non-response to infliximab; markers are needed to identify patients most likely to respond to treatment. We investigated whether production of tu
Publikováno v:
Gastroenterology. 150:S383
Publikováno v:
Gastroenterology. 140:S-487
Background: Mutations within the gene loci, encoding protein tyrosine phosphatase nonreceptor type 2 (PTPN2) and nucleotide oligomerization domain 2 (NOD2), have been associated with Crohn's disease (CD). We have recently shown that PTPN2 limits proi