Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Inka C Didelija"'
Autor:
Marina Martinez-Vargas, Arun Saini, Subhashree Pradhan, Luis Gardea, Barbara Stoll, Inka C. Didelija, K. Vinod Vijayan, Trung C. Nguyen, Miguel A. Cruz
Publikováno v:
Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-8 (2024)
Abstract Background Sepsis can lead to coagulopathy and microvascular thrombosis. Prior studies, including ours, reported an increased level of extracellular vimentin in blood derived from septic patients. Moreover, we identified the contribution of
Externí odkaz:
https://doaj.org/article/06bff839c9884f288ab548f6817a7e4b
Autor:
Trung C. Nguyen, MD, Juan C. Marini, DVM, PhD, Bobby Guillory, PhD, Christian Valladolid-Brown, PhD, Marina Martinez-Vargas, PhD, Deepika Subramanyam, PhD, Daniel Cohen, MD, PhD, Sonya C. Cirlos, BS, Fong Lam, MD, Barbara Stoll, PhD, Inka C. Didelija, Caitlin Vonderohe, DVM, Renan Orellana, MD, Arun Saini, MD, Subhashree Pradhan, PhD, Dalia Bashir, MD, Moreshwar S. Desai, MD, Saul Flores, MD, Manpreet Virk, MD, Hossein Tcharmtchi, MD, Amir Navaei, MD, Sheldon Kaplan, MD, Linda Lamberth, BS, Kristina G. Hulten, PhD, Brooks P. Scull, MS, Carl E. Allen, MD, PhD, Ayse Akcan-Arikan, MD, K. Vinod Vijayan, PhD, Miguel A. Cruz, PhD
Publikováno v:
Critical Care Explorations, Vol 5, Iss 6, p e0916 (2023)
CONTEXT:. Sepsis-induced coagulopathy leading to disseminated microvascular thrombosis is associated with high mortality and has no existing therapy. Despite the high prevalence of Gram-positive bacterial sepsis, especially methicillin-resistant Stap
Externí odkaz:
https://doaj.org/article/b1082c96a8b6421e9a346836afc51639
Autor:
Nhu Thao N. Galván, Samantha J. Paulsen, Ian S. Kinstlinger, Juan C. Marini, Inka C. Didelija, Dor Yoeli, Bagrat Grigoryan, Jordan S. Miller
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Recently developed biofabrication technologies are enabling the production of three-dimensional engineered tissues containing vascular networks which can deliver oxygen and nutrients across large tissue volumes. Tissues at this scale show promise for
Externí odkaz:
https://doaj.org/article/c739da42eca246c0b1ab995c1ebfd6fb
Publikováno v:
Physiological Reports, Vol 8, Iss 21, Pp n/a-n/a (2020)
Abstract Background Age‐dependent changes in the intestinal gene expression of enzymes involved in the metabolism of citrulline and arginine are well characterized. Enteroids, a novel ex‐vivo model that recreates the three‐dimensional structure
Externí odkaz:
https://doaj.org/article/780a0f439b40435dbdc5af726f845d47
Autor:
Chellakkan S. Blesson, Juan C. Marini, Inka C. Didelija, Shaji K. Chacko, Alexandra L. Gannon
Publikováno v:
Journal of visualized experiments : JoVE. (181)
Polycystic ovary syndrome (PCOS) is a common disease that results in disorders of glucose metabolism, such as insulin resistance and glucose intolerance. Dysregulated glucose metabolism is an important manifestation of the disease and is the key to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e6432d63aa1a1f599781352b1ff647
https://pubmed.ncbi.nlm.nih.gov/35312673
https://pubmed.ncbi.nlm.nih.gov/35312673
Autor:
Ian S. Kinstlinger, Bagrat Grigoryan, Jordan S. Miller, Samantha J. Paulsen, Inka C Didelija, Juan C. Marini, Dor Yoeli, Nhu Thao Nguyen Galvan
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Frontiers in Cardiovascular Medicine
Frontiers in Cardiovascular Medicine
Recently developed biofabrication technologies are enabling the production of three-dimensional engineered tissues containing vascular networks which can deliver oxygen and nutrients across large tissue volumes. Tissues at this scale show promise for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d592d4f81fcd2fec338fb1b6e0c2a6de
https://www.frontiersin.org/articles/10.3389/fcvm.2021.629313/full
https://www.frontiersin.org/articles/10.3389/fcvm.2021.629313/full
Publikováno v:
Am J Physiol Endocrinol Metab
Pegylated arginine deiminase (ADI-PEG20) results in the depletion of arginine with the production of isomolar amounts of citrulline. This citrulline has the potential to be utilized by the citrulline recycling pathway regenerating arginine and sustai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f50689df18f003e8daab69490e14e15
https://pubmed.ncbi.nlm.nih.gov/33427052
https://pubmed.ncbi.nlm.nih.gov/33427052
Publikováno v:
J Nutr
BACKGROUND: Sex differences in plasma concentration of arginine and arginase activity of different tissues have been reported in mice. In addition, male but not female C57BL/6 mice have a dietary arginine requirement for growth. OBJECTIVE: The goal o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfff89f9d0155d02bfd1a676b0c82ab
https://europepmc.org/articles/PMC7726119/
https://europepmc.org/articles/PMC7726119/
Publikováno v:
Physiological Reports, Vol 8, Iss 21, Pp n/a-n/a (2020)
Physiological Reports
Physiological Reports
Background Age‐dependent changes in the intestinal gene expression of enzymes involved in the metabolism of citrulline and arginine are well characterized. Enteroids, a novel ex‐vivo model that recreates the three‐dimensional structure of the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::917b981bce488d182c595f98b921a801
https://doi.org/10.14814/phy2.14565
https://doi.org/10.14814/phy2.14565
Autor:
Mahshid S. Azamian, Mahmoud A. Mohammad, Inka C Didelija, Sandesh C.S. Nagamani, Ann McMeans, Juan C. Marini, Umang Agarwal, Allison Tam
Publikováno v:
Genetics in Medicine. 23:2227
Benzoate and phenylbutyrate are widely used in the treatment of urea cycle disorders, but detailed studies on pharmacokinetics and comparative efficacy on nitrogen excretion are lacking. We conducted a randomized, three-arm, crossover trial in health
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::deb4c42e3cde5e6f0b8032b79591b6c2
https://doi.org/10.1038/s41436-021-01099-9
https://doi.org/10.1038/s41436-021-01099-9