Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Inka, Negwer"'
Autor:
Inka Negwer, Andreas Best, Meike Schinnerer, Olga Schäfer, Leon Capeloa, Manfred Wagner, Manfred Schmidt, Volker Mailänder, Mark Helm, Matthias Barz, Hans-Jürgen Butt, Kaloian Koynov
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
While nanocarrier-based drug delivery is a promising therapeutic approach, in situ characterization of drug nanocarriers in blood remains difficult. Here, the authors demonstrate how the fluorescence correlation spectroscopy can be used to directly c
Externí odkaz:
https://doaj.org/article/cf29261ca73b441fab35b8f08719a659
Autor:
Ilja Tabujew, Kaloian Koynov, Nadine Leber, Mark Helm, Christoph Freidel, Inka Negwer, Kalina Peneva, Katharina Landfester, Marleen Willig, Volker Mailänder, Rudolf Zentel
Publikováno v:
Acta Biomaterialia. 100:338-351
Bioengineering immune cells via gene therapy offers treatment opportunities for currently fatal viral infections. Also cell therapeutics offer most recently a breakthrough technology to combat cancer. These primary human cells, however, are sensitive
Autor:
Fatima Boukhallouk, Luise Florin, Krishnaraj Rajalingam, Frank Stubenrauch, Elena Wüstenhagen, Inka Negwer
Publikováno v:
Oncogene
The skin represents a physical and chemical barrier against invading pathogens, which is additionally supported by restriction factors that provide intrinsic cellular immunity. These factors detect viruses to block their replication cycle. Here, we u
Autor:
Thomas Fritz, Matthias Worm, Mark Helm, Sophie S. Müller, Holger Frey, Frank Roesch, Tobias L. Ross, Inka Negwer, Matthias Voigt, Kaloian Koynov, Kathrin Kettenbach
Publikováno v:
Chemistry - A European Journal. 22:11578-11582
Synthetic access to multiple surface decorations are a bottleneck in the development of liposomes for receptor mediated targeting. This opens a complex multiparameter space, exploration of which is severely limited in terms of sample numbers and turn
Autor:
Kaloian Koynov, Leon Capelôa, Manfred Schmidt, Volker Mailänder, Matthias Barz, Meike Schinnerer, Hans-Jürgen Butt, Inka Negwer, Mark Helm, Olga Schäfer, Andreas Best, Manfred Wagner
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Nature Communications, 9, 5306. NATURE PUBLISHING GROUP
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Nature Communications, 9, 5306. NATURE PUBLISHING GROUP
Nanocarrier-based drug delivery is a promising therapeutic approach that offers unique possibilities for the treatment of various diseases. However, inside the blood stream, nanocarriers’ properties may change significantly due to interactions with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a058bd1260cb6527e63a17585904bbdd
https://hdl.handle.net/1887/3147135
https://hdl.handle.net/1887/3147135
Autor:
Maike Baues, Willi Jahnen-Dechent, Michal Pechar, Fabian Kiessling, Robert Pola, Matthias Barz, Gert Storm, Twan Lammers, Inka Negwer, Benjamin Weber, Kaloian Koynov, Benjamin Theek, Felix Gremse
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society, 282, 25. Elsevier
Journal of controlled release, 282, 25-34. Elsevier
Journal of controlled release, 282, 25-34. Elsevier
Tumors are characterized by leaky blood vessels, and by an abnormal and heterogeneous vascular network. These pathophysiological characteristics contribute to the enhanced permeability and retention (EPR) effect, which is one of the key rationales fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a43e8b2867218dfff91c8102468c88e
https://dspace.library.uu.nl/handle/1874/376817
https://dspace.library.uu.nl/handle/1874/376817
Autor:
Kaloian Koynov, Julien Petit, Jennifer Schultze, Marcin Makowski, Oliver Bäumchen, Stephan Herminghaus, Katharina Landfester, Frederik R. Wurm, Laura Thomi, Inka Negwer
Publikováno v:
Soft Matter
The bottom-up approach in synthetic biology involves the engineering of synthetic cells by designing biological and chemical building blocks, which can be combined in order to mimic cellular functions. The first step for mimicking a living cell is th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd4c80fced96e45ba5e3e542b50cb03
https://hdl.handle.net/21.11116/0000-0000-B12E-521.11116/0000-0001-ED84-F
https://hdl.handle.net/21.11116/0000-0000-B12E-521.11116/0000-0001-ED84-F
Autor:
Ilja, Tabujew, Marleen, Willig, Nadine, Leber, Christoph, Freidel, Inka, Negwer, Kaloian, Koynov, Mark, Helm, Katharina, Landfester, Rudolf, Zentel, Kalina, Peneva, Volker, Mailänder
Publikováno v:
Acta biomaterialia. 100
Bioengineering immune cells via gene therapy offers treatment opportunities for currently fatal viral infections. Also cell therapeutics offer most recently a breakthrough technology to combat cancer. These primary human cells, however, are sensitive
Autor:
Hans-Jürgen Butt, Kaloian Koynov, Markus Hirsch, Tom Brown, Inka Negwer, Kalina Peneva, Stefka Kaloyanova, Mark Helm
Publikováno v:
ChemBioChem. 18(18)
Cyanine (Cy) dyes show a general propensity to localize in polarized mitochondria. This mitochondriotropism was used to perform a copper-free click reaction in the mitochondria of living cells. The in organello reaction of dyes Cy3 and Cy5 led to a p
Autor:
Elena Wüstenhagen, W. M. Kast, Inka Negwer, Gilles A. Spoden, Fatima Boukhallouk, Marc A. Schneider, Kaloian Koynov, Luise Florin, L. Hampe
Publikováno v:
Journal of virology. 90(23)
The human papillomavirus (HPV) capsid protein L2 is essential for viral entry. To gain a deeper understanding of the role of L2, we searched for novel cellular L2-interacting proteins. A yeast two-hybrid analysis uncovered the actin-depolymerizing fa