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of 9
pro vyhledávání: '"Injeong Cho"'
Autor:
Injeong Cho, Seohyun Lim, Minjae Kwon, Seung Min Chung, Jun Sung Moon, Ji Sung Yoon, Kyu Chang Won
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundCardiovascular autonomic neuropathy (CAN) is known to affect patients with diabetes mellitus (DM) and cause adverse renal outcomes. We aimed to analyze the association between CAN and diabetic kidney disease (DKD).MethodWe enrolled 254 DM p
Externí odkaz:
https://doaj.org/article/542c8d9dff864fc78a9949df8e43dd2d
Publikováno v:
Metabolites, Vol 12, Iss 11, p 1129 (2022)
BAM15 was recently screened as a protonophore uncoupler specifically for the mitochondrial membrane but not the plasma membrane. It is equally as potent as FCCP, but less toxic. Previously, mitochondrial uncoupling via DNP alleviates neurodegeneratio
Externí odkaz:
https://doaj.org/article/b2b9a400b15c435cb135f2cf84b6c028
Autor:
Darae Kim, Chi Young Shim, Geu-Ru Hong, Sungha Park, InJeong Cho, Hyuk-Jae Chang, Jong-Won Ha, Namsik Chung
Publikováno v:
Clinical Hypertension, Vol 23, Iss 1, Pp 1-7 (2017)
Abstract Background Arterial stiffness increases pressure load to the left ventricle (LV), leading to LV hypertrophy and subendocardial ischemia. Neurohormones stimulate myocardial fibrosis and LV dysfunction. We aimed to explore the associations of
Externí odkaz:
https://doaj.org/article/465a87cbaa7b4475a5b6a77259323fc3
Publikováno v:
Food Science & Nutrition
Food Science & Nutrition, 8(12):6633-6642
Food Science & Nutrition, 8(12):6633-6642
Dietary supplementation of flavonoids has been shown to reduce the severity of neurodegenerative disorders such as dementia, Parkinson's disease, and Alzheimer's disease by their antioxidant effects. However, their low bioavailabilityin vivo raises t
Publikováno v:
Molecules and Cells
Uncoupling proteins (UCPs) are mitochondrial inner membrane proteins that function to dissipate proton motive force and mitochondrial membrane potential. One UCP has been identified in Caenorhabditis elegans (C. elegans), namely UCP-4. In this study,
Publikováno v:
Molecules and Cells
C. elegans has two functional peroxidasins (PXN), PXN-1 and PXN-2. PXN-2 is essential to consolidate the extracellular matrix during development and is suggested to interact with PXN-1 antagonistically. pxn-1 is involved in neuronal development and p
Publikováno v:
Molecules and Cells
The uncoupling protein 4 (ucp-4) gene is involved in age-dependent neurodegeneration in C. elegans. Therefore, we aimed to investigate the mechanism underlying the association between mitochondrial uncoupling and neurodegeneration by examining the ef
Publikováno v:
Molecules and Cells
NOG1 is a nucleolar GTPase that is critical for 60S ribosome biogenesis. Recently, NOG1 was identified as one of the downstream regulators of target of rapamycin (TOR) in yeast. It is reported that TOR is involved in regulating lifespan and fat stora
Publikováno v:
Molecules and Cells
The Caenorhabditis elegans peroxidasins, PXN-1 and PXN-2, are extracellular peroxidases; pxn-2 is involved in muscle-epidermal attachment during embryonic morphogenesis and in specific axon guidance. Here we investigate potential roles of the other h