Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Inja, Waldhauer"'
Autor:
Anna Spreafico, Eva Muñoz Couselo, Anja Irmisch, Juliana Bessa, George Au-Yeung, Oliver Bechter, Inge Marie Svane, Miguel F. Sanmamed, Valentina Gambardella, Meredith McKean, Margaret Callahan, Reinhard Dummer, Christian Klein, Pablo Umaña, Nicole Justies, Florian Heil, Linda Fahrni, Eugenia Opolka-Hoffmann, Inja Waldhauer, Conrad Bleul, Roland F. Staack, Vaios Karanikas, Stephen Fowler
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionAlthough checkpoint inhibitors (CPIs) have improved outcomes for patients with metastatic melanoma, those progressing on CPIs have limited therapeutic options. To address this unmet need and overcome CPI resistance mechanisms, novel immun
Externí odkaz:
https://doaj.org/article/1b6cf328c2214d24859fac4cbcd710e0
Autor:
Arthur J. Van De Vyver, Antje-Christine Walz, Mariette S. Heins, Afsaneh Abdolzade-Bavil, Thomas E. Kraft, Inja Waldhauer, Michael B. Otteneder
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Monoclonal antibodies play an important role in the treatment of various diseases. However, the development of these drugs against neurological disorders where the drug target is located in the brain is challenging and requires a good understanding o
Externí odkaz:
https://doaj.org/article/3178277d91194c33ad0c97715f1819eb
Autor:
Inja Waldhauer, Valeria Gonzalez-Nicolini, Anne Freimoser-Grundschober, Tapan K Nayak, Linda Fahrni, Ralf J. Hosse, Danny Gerrits, Edwin J. W. Geven, Johannes Sam, Sabine Lang, Esther Bommer, Virginie Steinhart, Elisabeth Husar, Sara Colombetti, Erwin Van Puijenbroek, Markus Neubauer, J. Mark Cline, Pradeep K. Garg, Gregory Dugan, Federica Cavallo, Gonzalo Acuna, Jehad Charo, Volker Teichgräber, Stefan Evers, Otto C. Boerman, Marina Bacac, Ekkehard Moessner, Pablo Umaña, Christian Klein
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Simlukafusp alfa (FAP-IL2v, RO6874281/RG7461) is an immunocytokine comprising an antibody against fibroblast activation protein α (FAP) and an IL-2 variant with a retained affinity for IL-2Rβγ > IL-2 Rβγ and abolished binding to IL-2 Rα. Here,
Externí odkaz:
https://doaj.org/article/92299c28b9d34a45bf95cf39c2bbc494
Autor:
Christian Klein, Marina Bacac, Gerhard Niederfellner, Pablo Umana, Charles Dumontet, Michael Weidner, Helmut Burtscher, Ute Baer, Thomas Friess, Christian A. Gerdes, Lina Reslan, Minh Ngoc Duong, Sabine Lang, Erwin Van Puijenbroek, Doris Ziegler-Landesberger, Gunter Muth, Tanja Fauti, Tina Weinzierl, Inja Waldhauer, Olaf Mundigl, Frank Herting, Sylvia Herter
PDF file - 39K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b2e724fdabfc458384e7332209f44e
https://doi.org/10.1158/1535-7163.22497637.v1
https://doi.org/10.1158/1535-7163.22497637.v1
Autor:
Pablo Umaña, Klaus Bosslet, Christian Klein, Suzana Vega-Harring, Gary Xu, Peng Wang, Bin Liu, Cuiying Shao, Hadassah Sade, Werner Scheuer, Frank Herting, Thomas G. Weber, Ekkehard Mössner, Ralf J. Hosse, Sherif Daouti, Ningping Feng, Kathryn Packman, Huifeng Niu, Valeria Runza, Meher Majety, Barbara Weiser, Claudia Ferrara Koller, Inja Waldhauer, Sandra Grau-Richards, Thomas Friess, Katharina Wartha, Peter Brünker
Supplementary information on cell maintenance, and antibody selection and characterization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e363db33bfb70119118f019496cf74f
https://doi.org/10.1158/1535-7163.22507438.v1
https://doi.org/10.1158/1535-7163.22507438.v1
Autor:
Christian Klein, Marina Bacac, Gerhard Niederfellner, Pablo Umana, Charles Dumontet, Michael Weidner, Helmut Burtscher, Ute Baer, Thomas Friess, Christian A. Gerdes, Lina Reslan, Minh Ngoc Duong, Sabine Lang, Erwin Van Puijenbroek, Doris Ziegler-Landesberger, Gunter Muth, Tanja Fauti, Tina Weinzierl, Inja Waldhauer, Olaf Mundigl, Frank Herting, Sylvia Herter
We report the first preclinical in vitro and in vivo comparison of GA101 (obinutuzumab), a novel glycoengineered type II CD20 monoclonal antibody, with rituximab and ofatumumab, the two currently approved type I CD20 antibodies. The three antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310bb2ace40a382121e2a291bb303c28
https://doi.org/10.1158/1535-7163.c.6535675.v1
https://doi.org/10.1158/1535-7163.c.6535675.v1
Autor:
Pablo Umaña, Klaus Bosslet, Christian Klein, Suzana Vega-Harring, Gary Xu, Peng Wang, Bin Liu, Cuiying Shao, Hadassah Sade, Werner Scheuer, Frank Herting, Thomas G. Weber, Ekkehard Mössner, Ralf J. Hosse, Sherif Daouti, Ningping Feng, Kathryn Packman, Huifeng Niu, Valeria Runza, Meher Majety, Barbara Weiser, Claudia Ferrara Koller, Inja Waldhauer, Sandra Grau-Richards, Thomas Friess, Katharina Wartha, Peter Brünker
FAP-drozitumab antibody-mediated apoptosis does not correlate with DR5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3902da6fa0a7fedce1633f385c71997d
https://doi.org/10.1158/1535-7163.22507435.v1
https://doi.org/10.1158/1535-7163.22507435.v1
Autor:
Pablo Umaña, Klaus Bosslet, Christian Klein, Suzana Vega-Harring, Gary Xu, Peng Wang, Bin Liu, Cuiying Shao, Hadassah Sade, Werner Scheuer, Frank Herting, Thomas G. Weber, Ekkehard Mössner, Ralf J. Hosse, Sherif Daouti, Ningping Feng, Kathryn Packman, Huifeng Niu, Valeria Runza, Meher Majety, Barbara Weiser, Claudia Ferrara Koller, Inja Waldhauer, Sandra Grau-Richards, Thomas Friess, Katharina Wartha, Peter Brünker
Characterization and optimization of RG7386 dosing in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce9ad07c4aa7036fe31ed07f7a16bea
https://doi.org/10.1158/1535-7163.22507444.v1
https://doi.org/10.1158/1535-7163.22507444.v1
Autor:
Pablo Umaña, Klaus Bosslet, Christian Klein, Suzana Vega-Harring, Gary Xu, Peng Wang, Bin Liu, Cuiying Shao, Hadassah Sade, Werner Scheuer, Frank Herting, Thomas G. Weber, Ekkehard Mössner, Ralf J. Hosse, Sherif Daouti, Ningping Feng, Kathryn Packman, Huifeng Niu, Valeria Runza, Meher Majety, Barbara Weiser, Claudia Ferrara Koller, Inja Waldhauer, Sandra Grau-Richards, Thomas Friess, Katharina Wartha, Peter Brünker
Dysregulated cellular apoptosis and resistance to cell death are hallmarks of neoplastic initiation and disease progression. Therefore, the development of agents that overcome apoptosis dysregulation in tumor cells is an attractive therapeutic approa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::494461f0b5e8179b32511522a796418b
https://doi.org/10.1158/1535-7163.c.6538687.v1
https://doi.org/10.1158/1535-7163.c.6538687.v1
Autor:
Christian Klein, Marina Bacac, Gerhard Niederfellner, Pablo Umana, Charles Dumontet, Michael Weidner, Helmut Burtscher, Ute Baer, Thomas Friess, Christian A. Gerdes, Lina Reslan, Minh Ngoc Duong, Sabine Lang, Erwin Van Puijenbroek, Doris Ziegler-Landesberger, Gunter Muth, Tanja Fauti, Tina Weinzierl, Inja Waldhauer, Olaf Mundigl, Frank Herting, Sylvia Herter
PDF file - 43K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e716ea28e5fde081d3d479545b38e9
https://doi.org/10.1158/1535-7163.22497646.v1
https://doi.org/10.1158/1535-7163.22497646.v1