Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Inigo Barrio-Hernandez"'
Autor:
Aleš Holfeld, Dina Schuster, Fabian Sesterhenn, Alison K Gillingham, Patrick Stalder, Walther Haenseler, Inigo Barrio-Hernandez, Dhiman Ghosh, Jane Vowles, Sally A Cowley, Luise Nagel, Basavraj Khanppnavar, Tetiana Serdiuk, Pedro Beltrao, Volodymyr M Korkhov, Sean Munro, Roland Riek, Natalie de Souza, Paola Picotti
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 6, Pp 651-675 (2024)
Abstract The physical interactome of a protein can be altered upon perturbation, modulating cell physiology and contributing to disease. Identifying interactome differences of normal and disease states of proteins could help understand disease mechan
Externí odkaz:
https://doaj.org/article/111e459619b140979ac5a006ab8a5025
Autor:
Kornélia Szebényi, Inigo Barrio-Hernandez, George M. Gibbons, Luca Biasetti, Claire Troakes, Pedro Beltrao, András Lakatos
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Genome-wide association studies identified several disease-causing mutations in neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). However, the contribution of genetic variants to pathway disturbances and their cell t
Externí odkaz:
https://doaj.org/article/9f312bb3b5e94ae8a7325a17156a96fd
Autor:
Joel Selkrig, Megan Stanifer, André Mateus, Karin Mitosch, Inigo Barrio‐Hernandez, Mandy Rettel, Heeyoung Kim, Carlos G P Voogdt, Philipp Walch, Carmon Kee, Nils Kurzawa, Frank Stein, Clément Potel, Anna Jarzab, Bernhard Kuster, Ralf Bartenschlager, Steeve Boulant, Pedro Beltrao, Athanasios Typas, Mikhail M Savitski
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 2, Pp 1-13 (2021)
Abstract The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a global threat to human health and has compromised economic stability. In addition to the development of an effective vaccine, it is imperative to understand how SARS
Externí odkaz:
https://doaj.org/article/afece9f0c9684154826067b58f6e27a7
Publikováno v:
ACS Omega, Vol 6, Iss 8, Pp 5091-5100 (2021)
Externí odkaz:
https://doaj.org/article/81a42d54bea743f89e10a40ae53b74d3
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 8, Pp 1-3 (2021)
Abstract Since the start of 2020, the world has been upended by the pandemic caused by the severe acute respiratory coronavirus type 2 (SARS‐CoV‐2), the causative agent of coronavirus disease 2019 (COVID‐19). It has not only led to a tragic los
Externí odkaz:
https://doaj.org/article/590f821a2c1344ff9694c7ff9a22cbb3
Autor:
Martin Steinegger, Pedro Beltrao, Sameer Velankar, Mihaly Varadi, Tanita Wein, Cameron Gilchrist, Milot Mirdita, Jürgen Jänes, Jingi Yeo, Inigo Barrio-Hernandez
Proteins are key to all cellular processes and their structure is important in understanding their function and evolution. Sequence-based predictions of protein structures have increased in accuracy with over 214 million predicted structures availabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bbbef129f33b5bbb5d2724c7419bb6d
https://doi.org/10.21203/rs.3.rs-2727632/v1
https://doi.org/10.21203/rs.3.rs-2727632/v1
Autor:
Inigo Barrio-Hernandez, Jingi Yeo, Jürgen Jänes, Tanita Wein, Mihaly Varadi, Sameer Velankar, Pedro Beltrao, Martin Steinegger
Proteins are key to all cellular processes and their structure is important in understanding their function and evolution. Sequence-based predictions of protein structures have increased in accuracy with over 214 million predicted structures availabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6d3ef63952e999fae72f2483f4ef3a7
https://doi.org/10.1101/2023.03.09.531927
https://doi.org/10.1101/2023.03.09.531927
Autor:
Aleš Holfeld, Dina Schuster, Fabian Sesterhenn, Patrick Stalder, Walther Haenseler, Inigo Barrio-Hernandez, Dhiman Ghosh, Jane Vowles, Sally A. Cowley, Luise Nagel, Basavraj Khanppnavar, Pedro Beltrao, Volodymyr M. Korkhov, Roland Riek, Natalie de Souza, Paola Picotti
Protein–protein interactions (PPIs) mediate numerous essential functions and regulatory events in living organisms. The physical interactome of a protein can be abnormally altered in response to external and internal cues, thus modulating cell phys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa1cb0d23dc8c001a43c8d7aa361637
Autor:
Inigo Barrio-Hernandez, Jeremy Schwartzentruber, Anjali Shrivastava, Noemi del-Toro, Asier Gonzalez, Qian Zhang, Edward Mountjoy, Daniel Suveges, David Ochoa, Maya Ghoussaini, Glyn Bradley, Henning Hermjakob, Sandra Orchard, Ian Dunham, Carl A. Anderson, Pablo Porras, Pedro Beltrao
Publikováno v:
Nature Genetics, 55 (3)
Interacting proteins tend to have similar functions, influencing the same organismal traits. Interaction networks can be used to expand the list of candidate trait-associated genes from genome-wide association studies. Here, we performed network-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa83c627d04041e4fc3c3bbe9f7b3a34
Publikováno v:
ACS Omega
ACS Omega, Vol 6, Iss 8, Pp 5091-5100 (2021)
ACS Omega, Vol 6, Iss 8, Pp 5091-5100 (2021)
Protein degradation is a key component of the regulation of gene expression and is at the center of several pathogenic processes. Proteins are regularly degraded, but there is large variation in their lifetimes, and the kinetics of protein degradatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670f7a8aaa5820ab250c1418051f450c
http://europepmc.org/articles/PMC7931188
http://europepmc.org/articles/PMC7931188