Zobrazeno 1 - 10
of 448
pro vyhledávání: '"Inhibitory antibodies"'
Autor:
Nobukatsu Horita, Theresa M. Keeley, Elise S. Hibdon, Elizabeth Delgado, Daniel Lafkas, Christian W. Siebel, Linda C. Samuelson
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 275-287 (2022)
Background & Aims: Notch pathway signaling maintains gastric epithelial cell homeostasis by regulating stem cell proliferation and differentiation. We previously identified NOTCH1 and NOTCH2 as the key Notch receptors controlling gastric stem cell fu
Externí odkaz:
https://doaj.org/article/c9c7c90acdba43d3b35b4515ca88e447
Autor:
Jéssica R. S. Alves, Fernanda F. de Araújo, Camilla V. Pires, Andréa Teixeira-Carvalho, Barbara A. S. Lima, Letícia M. Torres, Francis B. Ntumngia, John H. Adams, Flora S. Kano, Luzia H. Carvalho
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Malaria remains a major public health problem worldwide, and Plasmodium vivax is the most widely distributed malaria parasite. Naturally acquired binding inhibitory antibodies (BIAbs) to region II of the Duffy binding protein (DBPII), a P. vivax liga
Externí odkaz:
https://doaj.org/article/628e62a8339048bfbb3308f79c6b28e1
Publikováno v:
Inflammation and Regeneration, Vol 38, Iss 1, Pp 1-8 (2018)
Abstract Monoclonal antibody (mAb) is an essential tool for the analysis in various fields of biology. In the field of innate immunology, mAbs have been established and used for the study of Toll-like receptors (TLRs), a family of pathogen sensors th
Externí odkaz:
https://doaj.org/article/1b839c6f80bc495385f5fbb5fbd6c50a
Akademický článek
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Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Gonadotropins are essential for reproduction control in humans as well as in animals. They are widely used all over the world for ovarian stimulation in women, spermatogenesis stimulation in men, and ovulation induction and superovulation in animals.
Externí odkaz:
https://doaj.org/article/9f01e6ef02064cfcb38eb7f22c7e87bb
Autor:
Elise S. Hibdon, Elizabeth Delgado, Nobukatsu Horita, Theresa M. Keeley, Daniel Lafkas, Linda C. Samuelson, Christian W. Siebel
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 275-287 (2022)
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 275-287 (2022)
Background & Aims Notch pathway signaling maintains gastric epithelial cell homeostasis by regulating stem cell proliferation and differentiation. We previously identified NOTCH1 and NOTCH2 as the key Notch receptors controlling gastric stem cell fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccacea6aeb7ccb4eac58ae85430d9382
https://doi.org/10.1016/j.jcmgh.2021.08.012
https://doi.org/10.1016/j.jcmgh.2021.08.012
Autor:
Joshua Hay, Peter P. Toth, Carlota Oleaga, Joshua Miles, Nathalie Pamir, Jonathan Q. Purnell, Emily Friz, Cecilia Huang, Sergio Fazio, Paul Mueller, Michael D. Shapiro, P. Barton Duell, Bruce A. Warden, Cezary Wojcik, Hagai Tavori
Publikováno v:
Journal of the American College of Cardiology
BACKGROUND Monoclonal antibodies against proprotein convertase subtilisin/kexin type 9 (PCSK9i) lower LDL-C by up to 60% and increase plasma proprotein convertase subtilisin/kexin type 9 (PCSK9) levels by 10-fold. OBJECTIVES The authors studied the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b710b0270442e1f104907b6eb98611f1
https://doi.org/10.1016/j.jacc.2021.07.056
https://doi.org/10.1016/j.jacc.2021.07.056
Autor:
Yongfeng Fan, Jianbo Dong, Jianlong Lou, Weihua Wen, Fraser Conrad, Isin N. Geren, Consuelo Garcia-Rodriguez, Theresa J. Smith, Leonard A. Smith, Mengfei Ho, Melissa Pires-Alves, Brenda A. Wilson, James D. Marks
Publikováno v:
Toxins, Vol 7, Iss 9, Pp 3405-3423 (2015)
Existing antibodies (Abs) used to treat botulism cannot enter the cytosol of neurons and bind to botulinum neurotoxin (BoNT) at its site of action, and thus cannot reverse paralysis. However, Abs targeting the proteolytic domain of the toxin could in
Externí odkaz:
https://doaj.org/article/6b1b373bea8b45a2adb6651086bec8a0
Publikováno v:
npj Systems Biology and Applications, Vol 7, Iss 1, Pp 1-8 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
NPJ Systems Biology and Applications
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
NPJ Systems Biology and Applications
Hemophilia A is a relatively rare hereditary coagulation disorder caused by a defective F8 gene resulting in a dysfunctional Factor VIII protein (FVIII). This condition impairs the coagulation cascade, and if left untreated, it causes permanent joint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79ac4e4a35ba12cc9ba7adcc9a63103
https://doaj.org/article/fb1b7a4cc993467793807c51e24d59c8
https://doaj.org/article/fb1b7a4cc993467793807c51e24d59c8
Autor:
Ivan Peyron, Delphine Borgel, Dominique Lasne, Thibaud Sefiane, Peter J. Lenting, Caterina Casari, Maximilien Desvages, Stéphanie Chhun, Cécile Bally, Laurent Frenzel, Annie Harroche
Publikováno v:
Haematologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846a30cce30e6e6814dde8d165e46b59
http://europepmc.org/articles/PMC8327735
http://europepmc.org/articles/PMC8327735