Zobrazeno 1 - 10 of 149 pro vyhledávání: '"Inhibitory G-protein"'
1
Structural basis for recognition of anti-migraine drug lasmiditan by the serotonin receptor 5-HT1F–G protein complex
Autor: Yumu Zhang, H. Eric Xu, Yangxia Tan, Peiyu Xu, Sijie Huang, Yi Jiang, Chongzhao You
Publikováno v: Cell Research. 31:1036-1038
Migraine headache has become global pandemics and is the number one reason of work day loss. The most common drugs for anti-migraine are the triptan class of drugs that are agonists for serotonin receptors 5-HT1B and 5-HT1D. However, these drugs have
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c79ea29a4180a559e4efaaec5b73254
https://doi.org/10.1038/s41422-021-00527-4
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2
Structural basis for recognition of anti-migraine drug lasmiditan by the serotonin receptor 5-HT1F–G protein complex
Autor: Peiyu Xu, Yangxia Tan, Yumu Zhang, Sijie Huang, Yi Jiang, Chongzhao You, H. Eric Xu
Migraine headache has become global pandemics and is the number one reason of work day loss. The most common drugs for anti-migraine are the triptan class of drugs that are agonists for serotonin receptors 5-HT1B and 5-HT1D. However, these drugs have
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a21bbe1a9be5358ffb1c2c1be81d88e3
https://doi.org/10.1101/2021.05.29.446083
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3
Akademický článek
The role of inhibitory G proteins and regulators of G protein signalling in the in-vivo control of heart rate and predisposition to cardiac arrhythmias
Autor: Richard eAng, Aaisha eOpel, Andrew eTinker
Publikováno v: Frontiers in Physiology, Vol 3 (2012)
Inhibitory heterotrimeric G-proteins and the control of heart rate.The activation of cell signalling pathways involving inhibitory heterotrimeric G-proteins acts to slow the heart rate via modulation of ion channels. A large number of RGSs can act as
Externí odkaz: https://doaj.org/article/8a18a6b1d4dc40c8814f686f4cf494cc
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4
Akademický článek
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5
Optogenetic silencing at synaptic terminals
Autor: Nina Vogt
Publikováno v: Neuron
Optical manipulations of genetically defined cell types have generated significant insights into the dynamics of neural circuits. While optogenetic activation has been relatively straightforward, rapid and reversible synaptic inhibition has proven mo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cea49c06f2188e55f7c42d978e9197ec
https://doi.org/10.1038/s41592-021-01212-5
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