Protein kinase C-induced activin A switches adrenocortical steroidogenesis to aldosterone by suppressing CYP17A1 expression

Autor: Marco Eijken, Frank H. de Jong, Geert Kazemier, Richard A Feelders, Francien H van Nederveen, Johannes Hofland, Jacobie Steenbergen, Peter M. van Koetsveld, Wouter W. de Herder, Leo J. Hofland

Publikováno v: Hofland, J, Steenbergen, J, Hofland, L J, van Koetsveld, P M, Eijken, M, van Nederveen, F H, Kazemier, G, de Herder, W W, Feelders, R A & de Jong, F H 2013, ' Protein kinase C-induced activin A switches adrenocortical steroidogenesis to aldosterone by suppressing CYP17A1 expression ', A J P: Endocrinology and Metabolism (Online), vol. 305, no. 6, pp. E736-44 . https://doi.org/10.1152/ajpendo.00034.2013
American Journal of Physiology, Endocrinology and Metabolism, 305(6), E736-E744. American Physiological Society

Functional zonation of the adrenal cortex is a consequence of the zone-specific expression of P450c17 ( CYP17A1) and its cofactors. Activin and inhibin peptides are differentially produced within the zones of the adrenal cortex and have been implicat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ee586e96bef6c73e644fd94ca3e60e
https://doi.org/10.1152/ajpendo.00034.2013

The N-myc oncogene in human neuroblastoma cells: down-regulation of an angiogenesis inhibitor identified as activin A

Autor: Breit S, Ashman K, Wilting J, Jochen Rössler, Hatzi E, Fotsis T, Schweigerer L

Publikováno v: Scopus-Elsevier
Europe PubMed Central

Angiogenesis, the formation of new blood vessels, is seen during embryonic development and tumor progression, but the mechanisms have remained unclear. Recent data indicate that developmental and tumor angiogenesis can be induced by cellular oncogene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5c7b7dcd9630419fb522ef76ff66e0f5
http://olympias.lib.uoi.gr/jspui/handle/123456789/23865