Zobrazeno 1 - 10
of 244
pro vyhledávání: '"Inhee, Choi"'
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1, Pp 51-66 (2023)
ARS-interacting multifunctional proteins 2 (AIMP2) is known to be a powerful tumour suppressor. However, the target AIMP2-DX2, AIMP2-lacking exon 2, is often detected in many cancer patients and cells. The predominant approach for targeting AIMP-DX2
Externí odkaz:
https://doaj.org/article/7b2ee4a801084b17b8b7db733202f13c
Autor:
Seungki Lee, Subeen Kim, Doyun Kim, Jieun You, Ji Soo Kim, Hakchun Kim, Jungwon Park, Jihwan Song, Inhee Choi
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background Spatiotemporal regulation is one of the major considerations for developing a controlled and targeted drug delivery system to treat diseases efficiently. Light-responsive plasmonic nanostructures take advantage due to their tunabl
Externí odkaz:
https://doaj.org/article/d8d7e3e1445244a38af58b2c6cbd6e5b
Autor:
Diego Benítez, Jaime Franco, Florencia Sardi, Alejandro Leyva, Rosario Durán, Gahee Choi, Gyongseon Yang, Taehee Kim, Namyoul Kim, Jinyeong Heo, Kideok Kim, Honggun Lee, Inhee Choi, Constantin Radu, David Shum, Joo Hwan No, Marcelo A. Comini
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 912-929 (2022)
Trypanothione synthetase (TryS) catalyses the synthesis of N1,N8-bis(glutathionyl)spermidine (trypanothione), which is the main low molecular mass thiol supporting several redox functions in trypanosomatids. TryS attracts attention as molecular targe
Externí odkaz:
https://doaj.org/article/d6287e9bbb0746028794672207991f63
Autor:
Su-Yeon Lee, Sanghwa Kim, Inhee Choi, Yeonhwa Song, Namjeong Kim, Hyung Chul Ryu, Jee Woong Lim, Hyo Jin Kang, Jason Kim, Haeng Ran Seo
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-11 (2022)
Abstract 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) is a key enzyme that catalyzes the intracellular conversion of cortisone to physiologically active cortisol. Although 11βHSD1 has been implicated in numerous metabolic syndromes, such as o
Externí odkaz:
https://doaj.org/article/36fb516f0e0e4b41a7a98bd1d3942c9d
Publikováno v:
Advanced Science, Vol 10, Iss 23, Pp n/a-n/a (2023)
Abstract While breathing, alveoli are exposed to external irritants, which contribute to the pathogenesis of lung disease. Therefore, in situ monitoring of alveolar responses to stimuli of toxicants under in vivo environments is important to understa
Externí odkaz:
https://doaj.org/article/1ce8e7adc63844e6adb99badc09da3c1
Autor:
Hakchun Kim, Hyun Ji An, Junhee Park, Yohan Lee, Min Seob Kim, Seungki Lee, Nam Dong Kim, Jihwan Song, Inhee Choi
Publikováno v:
Nano Convergence, Vol 9, Iss 1, Pp 1-12 (2022)
Abstract Reactive oxygen species (ROS) regulate various physiological and pathological conditions in cells by interacting with signaling molecules and inducing oxidative stress. Therefore, sensitive monitoring of ROS levels in living cells is importa
Externí odkaz:
https://doaj.org/article/d538c958b9f1432eb19e680a7559a886
Autor:
Jinyeong Heo, Dahae Koh, Minjeong Woo, Doyoon Kwon, Virgínia Carla de Almeida Falcão, Connor Wood, Honggun Lee, Kideok Kim, Inhee Choi, Jichan Jang, Priscille Brodin, David Shum, Vincent Delorme
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Para-aminosalicylic acid (PAS) is an antibiotic that was largely used for the multi-therapy of tuberculosis in the twentieth century. To try to overcome the inconvenience of its low efficacy and poor tolerance, we searched for novel chemical
Externí odkaz:
https://doaj.org/article/cb73924f711a4011ae020b9651801daa
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The authors demonstrate a colourimetric imaging method using plasmonic nanoparticles for visualisation of heterochromatin histone markers. Based on the distance-dependent coupling effect, resulting in spectral shifts, they observe reorganisation of h
Externí odkaz:
https://doaj.org/article/236b82e720364340bdcc3a69cfe80ee0
Autor:
Sanghwa Kim, Minji Lee, Yeonhwa Song, Su-Yeon Lee, Inhee Choi, I-Seul Park, Jiho Kim, Jin-sun Kim, Kang mo Kim, Haeng Ran Seo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-18 (2021)
Abstract Background Hepatocellular carcinoma (HCC) is one of the most common malignant cancers worldwide, and liver cancer has increased in mortality due to liver cancer because it was detected at an advanced stages in patients with liver dysfunction
Externí odkaz:
https://doaj.org/article/e5f2ab7eaab24620b6335ddbce5e7714
Autor:
Hyung Chul Ryu, Marc Windisch, Jee Woong Lim, Inhee Choi, Eun Kyu Lee, Hye Hyun Yoo, Tae Kon Kim
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 462-468 (2021)
To develop unique small-molecule inhibitors of hepatitis C virus (HCV), thiophen urea (TU) derivatives were synthesised and screened for HCV entry inhibitory activities. Among them, seven TU compounds exhibited portent anti-viral activities against g
Externí odkaz:
https://doaj.org/article/f0c396f876fc46c69ff6a4c1280f3573