Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Ingunn Bakke"'
Autor:
Elin Synnøve Røyset, Henrik P Sahlin Pettersen, Weili Xu, Anis Larbi, Arne K Sandvik, Sonja E Steigen, Ignacio Catalan‐Serra, Ingunn Bakke
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 9, Iss 1, Pp 18-31 (2023)
Abstract Colon mucosae of ulcerative colitis (UC) and Crohn's disease (CD) display differences in the number and distribution of immune cells that are difficult to assess by eye. Deep learning‐based analysis on whole slide images (WSIs) allows extr
Externí odkaz:
https://doaj.org/article/50ead8b7e1914159a0fc47294967fc30
Autor:
Shreya Gopalakrishnan, Ingunn Bakke, Marianne Doré Hansen, Helene Kolstad Skovdahl, Atle van Beelen Granlund, Arne K. Sandvik, Torunn Bruland
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
There are many unanswered questions regarding responses to proinflammatory signals in intestinal epithelial cells (IECs). For example, chemokines secreted by IECs upon external stimuli play multifunctional roles in both homeostasis and during inflamm
Externí odkaz:
https://doaj.org/article/1c8497207a054ee8830b29b10212250a
Autor:
Gunnar Andreas Walaas, Shreya Gopalakrishnan, Ingunn Bakke, Helene Kolstad Skovdahl, Arnar Flatberg, Ann Elisabet Østvik, Arne Kristian Sandvik, Torunn Bruland
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThe epithelium in the colonic mucosa is implicated in the pathophysiology of various diseases, including inflammatory bowel diseases and colorectal cancer. Intestinal epithelial organoids from the colon (colonoids) can be used for disease m
Externí odkaz:
https://doaj.org/article/01ada229198b4632b1acd85dc3ea4dd7
Autor:
Shreya Gopalakrishnan, Marianne Doré Hansen, Helene Kolstad Skovdahl, Ingrid Aass Roseth, Atle van Beelen Granlund, Ann Elisabet Østvik, Ingunn Bakke, Arne Kristian Sandvik, Torunn Bruland
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Major Histocompatibility Complex (MHC)-I and -II genes are upregulated in intestinal epithelial cells (IECs) during active inflammatory bowel diseases (IBD), but little is known about how IBD-relevant pro-inflammatory signals and IBD drugs can regula
Externí odkaz:
https://doaj.org/article/89a246f92a1147c7afde661523747fdc
Autor:
Henrik Sahlin Pettersen, Ilya Belevich, Elin Synnøve Røyset, Erik Smistad, Melanie Rae Simpson, Eija Jokitalo, Ingerid Reinertsen, Ingunn Bakke, André Pedersen
Publikováno v:
Frontiers in Medicine, Vol 8 (2022)
Application of deep learning on histopathological whole slide images (WSIs) holds promise of improving diagnostic efficiency and reproducibility but is largely dependent on the ability to write computer code or purchase commercial solutions. We prese
Externí odkaz:
https://doaj.org/article/6ad698dcbbef4ffb9a2381ce7a518097
Autor:
Siri Sæterstad, Ann Elisabet Østvik, Elin Synnøve Røyset, Ingunn Bakke, Arne Kristian Sandvik, Atle van Beelen Granlund
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
In recent years it has become apparent that the epithelium is highly involved in inflammatory bowel disease (IBD) pathophysiology. The majority of gene expression studies of IBD are generated from heterogeneous biopsies, providing no distinction betw
Externí odkaz:
https://doaj.org/article/28890aa35b7444e682e28e443e7979b1
Autor:
Helene Kolstad Skovdahl, Shreya Gopalakrishnan, Tarjei Dahl Svendsen, Atle van Beelen Granlund, Ingunn Bakke, Zekarias G. Ginbot, Silje Thorsvik, Arnar Flatberg, Bjørnar Sporsheim, Jenny Ostrop, Tom Eirik Mollnes, Arne Kristian Sandvik, Torunn Bruland
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Treatment of inflammatory bowel disease (IBD) is challenging, with a series of available drugs each helping only a fraction of patients. Patients may face time-consuming drug trials while the disease is active, thus there is an unmet need for biomark
Externí odkaz:
https://doaj.org/article/23107a23c1a647daa8ee051009ee1d4a
Autor:
Kristin Matre Aasarød, Helge Lyder Waldum, Astrid Kamilla Stunes, Arne Kristian Sandvik, Arnar Flatberg, Patricia Mjønes, Unni Syversen, Ingunn Bakke, Reidar Fossmark
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 927 (2020)
Proton pump inhibitor use is associated with an increased risk of gastric cancer, which may be mediated by hypergastrinemia. Spasmolytic polypeptide-expression metaplasia (SPEM) has been proposed as a precursor of gastric cancer. We have examined the
Externí odkaz:
https://doaj.org/article/13841f5d4fe04090a7d2883254d35a0f
Autor:
Pål Vange, Torunn Bruland, Berit Doseth, Reidar Fossmark, Mirta M L Sousa, Vidar Beisvag, Øystein Sørdal, Gunnar Qvigstad, Helge L Waldum, Arne K Sandvik, Ingunn Bakke
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184514 (2017)
The cytoprotective protein clusterin is often dysregulated during tumorigenesis, and in the stomach, upregulation of clusterin marks emergence of the oxyntic atrophy (loss of acid-producing parietal cells)-associated spasmolytic polypeptide-expressin
Externí odkaz:
https://doaj.org/article/c733e76aeaeb4867accf8af17913da8d
Autor:
Helene Kolstad Skovdahl, Atle van Beelen Granlund, Ann Elisabet Østvik, Torunn Bruland, Ingunn Bakke, Sverre Helge Torp, Jan Kristian Damås, Arne Kristian Sandvik
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0141710 (2015)
The chemokine CCL20 and its receptor CCR6 are putative drug targets in inflammatory bowel disease, and CCL20 is a novel IBD predilection gene. Previous findings on the CCL20 response in these diseases are divergent. This study was undertaken to exami
Externí odkaz:
https://doaj.org/article/2ad252640ed742f283639bd6a9d181b4