Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Ingrid van der Heijden"'
Autor:
Jinhyuk Bhin, Mariana Paes Dias, Ewa Gogola, Frank Rolfs, Sander R. Piersma, Roebi de Bruijn, Julian R. de Ruiter, Bram van den Broek, Alexandra A. Duarte, Wendy Sol, Ingrid van der Heijden, Christina Andronikou, Taina S. Kaiponen, Lara Bakker, Cor Lieftink, Ben Morris, Roderick L. Beijersbergen, Marieke van de Ven, Connie R. Jimenez, Lodewyk F.A. Wessels, Sven Rottenberg, Jos Jonkers
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112538- (2023)
Summary: BRCA1 and BRCA2 both function in DNA double-strand break repair by homologous recombination (HR). Due to their HR defect, BRCA1/2-deficient cancers are sensitive to poly(ADP-ribose) polymerase inhibitors (PARPis), but they eventually acquire
Externí odkaz:
https://doaj.org/article/fd908dcc7cb748d2901dfd4eb935d917
Autor:
Marlous Hoogstraat, Esther H. Lips, Isabel Mayayo-Peralta, Lennart Mulder, Petra Kristel, Ingrid van der Heijden, Stefano Annunziato, Maartje van Seijen, Petra M. Nederlof, Gabe S. Sonke, Wilbert Zwart, Jelle Wesseling, Lodewyk F. A. Wessels
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract When locally advanced breast cancer is treated with neoadjuvant chemotherapy, the recurrence risk is significantly higher if no complete pathologic response is achieved. Identification of the underlying resistance mechanisms is essential to
Externí odkaz:
https://doaj.org/article/2615d770ea91484288e3fc2c9c92bdc1
Autor:
Yandisa Sikweyiya, Erin Stern, Jill Hanass-Hancock, Ingrid van der Heijden, Henri Myrttinen, Adolphina Addoley Addo-Lartey, Kristin Dunkle
Publikováno v:
BMC Public Health, Vol 22, Iss 1, Pp 1-15 (2022)
Abstract Background Gender-transformative work in the Global South often focuses on transforming ‘toxic masculinities’ to prevent intimate partner violence (IPV), but there has been little research on whether and how constructions of masculinitie
Externí odkaz:
https://doaj.org/article/941730b066fa4dc5bbb06be3b5592901
Autor:
Rozina Somani, Julienne Corboz, Rozina Karmaliani, Esnat D. Chirwa, Judith McFarlane, Hussain Maqbool Ahmed Khuwaja, Nargis Asad, Yasmeen Somani, Ingrid Van Der Heijden, Rachel Jewkes
Publikováno v:
Global Health Action, Vol 14, Iss 1 (2021)
Background: Children with disabilities are more likely to experience violence or injury at school and at home, but there is little evidence from Central Asia. Objective: To describe the prevalence of disability and associations with peer violence per
Externí odkaz:
https://doaj.org/article/e4946cef6ee249e69a4b51626c328c82
Autor:
Andrew Gibbs, Esnat Chirwa, Kristin Dunkle, Erin Stern, Ingrid Van Der Heijden, Laura Washington
Publikováno v:
BMJ Global Health, Vol 5, Iss 12 (2020)
Introduction Women with disabilities experience higher rates of intimate partner violence (IPV) than women without disabilities. There remains limited evidence about whether IPV prevention interventions for the general population have benefits for wo
Externí odkaz:
https://doaj.org/article/3e5b280b80a140cca8606ebc9bc335ef
Publikováno v:
BMJ Global Health, Vol 5, Iss 11 (2020)
Introduction Intimate partner violence (IPV) is a serious public health and human rights violation which impacts approximately one in three women worldwide. Some existing evidence suggests that women with disabilities are at higher risk of IPV, but i
Externí odkaz:
https://doaj.org/article/0eedf72b0ada4724a36f372ae9540295
Autor:
Sjoerd Klarenbeek, Chris W. Doornebal, Sjors M. Kas, Nicola Bonzanni, Jinhyuk Bhin, Tanya M. Braumuller, Ingrid van der Heijden, Mark Opdam, Philip C. Schouten, Kelly Kersten, Roebi de Bruijn, Daniel Zingg, Julia Yemelyanenko, Lodewyk F.A. Wessels, Karin E. de Visser, Jos Jonkers
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Effective treatment of invasive lobular carcinoma (ILC) of the breast is hampered by late detection, invasive growth, distant metastasis, and poor response to chemotherapy. Phosphoinositide 3-kinase (PI3K) signaling, one of the major druggable oncoge
Externí odkaz:
https://doaj.org/article/54b9a172c50d4990871cfc2608c09c9c
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178135 (2017)
Developing interventions that address psychosocial wellbeing of people living with HIV is critical to ensure strong linkages to and retention in HIV care. This paper describes the development of Sondela, an HIV adjustment and coping intervention for
Externí odkaz:
https://doaj.org/article/0976250a944f4250950ade80c94eecc2
Autor:
Abdelghani Mazouzi, Sarah C. Moser, Federico Abascal, Bram van den Broek, Martin Del Castillo Velasco-Herrera, Ingrid van der Heijden, Maarten Hekkelman, Anne Paulien Drenth, Eline van der Burg, Lona J. Kroese, Kees Jalink, David J. Adams, Jos Jonkers, Thijn R. Brummelkamp
Publikováno v:
Science Advances. 9
DNA interstrand crosslinks (ICLs) pose a major obstacle for DNA replication and transcription if left unrepaired. The cellular response to ICLs requires the coordination of various DNA repair mechanisms. Homologous recombination (HR) intermediates ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e6e7cedd9db10221bdcfd61f019d11d
https://doi.org/10.1126/sciadv.adf4409
https://doi.org/10.1126/sciadv.adf4409
Autor:
Jos Jonkers, Frans B.L. Hogervorst, Jost Seibler, Ellen Wientjens, Mark Pieterse, Pramudita Prasetyanti, Christiaan N. Klijn, Rinske Drost, Ingrid van der Heijden, Hanneke van der Gulden, Peter Bouwman
Supplementary Methods - PDF 55K, A detailed protocol for the classification of BRCA1 sequence variants using R26CreERT2/RMCE;Brca1SCo/{delta} ES cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::068d5af15587535ab78cd5d5eaacd641
https://doi.org/10.1158/2159-8290.22528938
https://doi.org/10.1158/2159-8290.22528938
