Antibodies against apoB100 peptide 210 inhibit atherosclerosis in apoE-/- mice

Autor: Pontus Dunér, Ingrid Yao Mattisson, Per Fogelstrand, Lars Glise, Stacey Ruiz, Christopher Farina, Jan Borén, Jan Nilsson, Eva Bengtsson

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

Abstract Atherosclerotic plaques are characterized by an accumulation and subsequent oxidation of LDL, resulting in adaptive immune responses against formed or exposed neoepitopes of the LDL particle. Autoantibodies against native p210, the 3136–31

Externí odkaz: https://doaj.org/article/155b069540a744b0905d0437eeb14b5a

Myocardin Family Members Drive Formation of Caveolae.

Autor: Katarzyna K Krawczyk, Ingrid Yao Mattisson, Mari Ekman, Nikolay Oskolkov, Rebecka Grantinge, Dorota Kotowska, Björn Olde, Ola Hansson, Sebastian Albinsson, Joseph M Miano, Catarina Rippe, Karl Swärd

Publikováno v: PLoS ONE, Vol 10, Iss 8, p e0133931 (2015)

Caveolae are membrane organelles that play roles in glucose and lipid metabolism and in vascular function. Formation of caveolae requires caveolins and cavins. The make-up of caveolae and their density is considered to reflect cell-specific transcrip

Externí odkaz: https://doaj.org/article/2203c6483d104681a8d3583864d7d686

Lack of Ability to Present Antigens on Major Histocompatibility Complex Class II Molecules Aggravates Atherosclerosis in ApoE −/− Mice

Autor: Lena Sundius, Jan Nilsson, Ragnar Alm, Lukas Tomas, Sara Rattik, Harry Björkbacka, Ingrid Yao Mattisson, Gunilla Nordin Fredrikson, Ingrid Söderberg, Irena Ljungcrantz, Caitriona Grönberg, Maria Wigren

Publikováno v: Circulation. 139:2554-2566

Background: Hypercholesterolemic mice lacking factors required for activation of CD4 + T cells are characterized by reduced development of atherosclerosis. Consequently, it has been assumed that atherosclerosis involves loss of tolerance against modi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc7598f36cd49a3fab3e0862e77b12bf
https://doi.org/10.1161/circulationaha.118.039288

Apolipoprotein M and its impact on endothelial dysfunction and inflammation in the cardiovascular system

Autor: Ingrid Yao Mattisson, Christina Christoffersen

Publikováno v: Yao Mattisson, I & Christoffersen, C 2021, ' Apolipoprotein M and its impact on endothelial dysfunction and inflammation in the cardiovascular system ', Atherosclerosis, vol. 334, pp. 76-84 . https://doi.org/10.1016/j.atherosclerosis.2021.08.039

Apolipoprotein M (apoM) is a member of the lipocalin superfamily and is predominantly associated with high-density lipoprotein (HDL). It was found that apoM is the chaperon to the bioactive sphingolipid, sphingosine-1-phosphate (S1P). Several studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b1a93ebb0b7072618a84dda52037a2
https://pubmed.ncbi.nlm.nih.gov/34482091

Immune responses against oxidized LDL as possible targets for prevention of atherosclerosis in systemic lupus erythematosus

Autor: Michael Lebens, Ingrid Yao Mattisson, Gunilla Nordin Fredrikson, Anders A. Bengtsson, Sara Rattik, Jan Holmgren, Harry Björkbacka, Irena Ljungcrantz, Maria Wigren, Birgitta Gullstrand, Manuela Terrinoni, Jan Nilsson

Publikováno v: Vascular pharmacology. 140

Patients suffering from systemic lupus erythematosus (SLE) are at increased risk of developing cardiovascular disease (CVD) and traditional therapies including statins provide insufficient protection. Impaired removal of apoptotic material is a commo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab8228792d48e4e06dc2b4b4ad633c65
https://pubmed.ncbi.nlm.nih.gov/33857652