Macrophages and Dendritic Cells Are the Predominant Cells Infected in Measles in Humans

Autor: Ingrid V. Allen, Stephen McQuaid, Rosana Penalva, Martin Ludlow, W. Paul Duprex, Bertus K. Rima

Publikováno v: mSphere, Vol 3, Iss 3 (2018)

ABSTRACT Characterization of human measles cases is essential in order to better assess the data generated in model systems of morbillivirus infection. To this end, we collected formalin-fixed tissue samples from 23 natural measles cases from differe

Externí odkaz: https://doaj.org/article/1774f0a666714a1b9590c746ce02b8c6

Regulatory T cells promote myelin regeneration in the central nervous system

Autor: Amanda Boyd, Samara Fleville, Bernard Perbal, Ingrid V. Allen, Chao Zhao, Sonia R. Mayoral, Jonah R. Chan, Yvonne Dombrowski, Adrien Kissenpfennig, Rosana Penalva, Denise C. Fitzgerald, Emma Evergren, Rebecca J. Ingram, Marie Dittmer, Michelle Naughton, Jill Moffat, Peter Bankhead, Anna Williams, Rachel Hassan, Robin J.M. Franklin, Thomas O'Hagan, Peter W. Hamilton, Paul N. Moynagh, Georgios Eleftheriadis, John Falconer

Publikováno v: Nature neuroscience, vol 20, iss 5
Dombrowski, Y, O'Hagan, T, Dittmer, M, Penalva, R, Mayoral, S R, Bankhead, P, Fleville, S, Eleftheriadis, G, Zhao, C, Naughton, M, Hassan, R, Moffat, J, Falconer, J, Boyd, A, Hamilton, P, Allen, I V, Kissenpfennig, A, Moynagh, P N, Evergren, E, Perbal, B, Williams, A C, Ingram, R J, Chan, J R, Franklin, R J M & Fitzgerald, D C 2017, ' Regulatory T cells promote myelin regeneration in the central nervous system ', Nature Neuroscience, vol. 20, no. 5, pp. 674–680 . https://doi.org/10.1038/nn.4528
Nature neuroscience

Regeneration of CNS myelin involves differentiation of oligodendrocytes from oligodendrocyte progenitor cells. In multiple sclerosis, remyelination can fail despite abundant oligodendrocyte progenitor cells, suggesting impairment of oligodendrocyte d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be3ce4f91d7de556191ca602f2bee463
https://doi.org/10.1038/nn.4528

Ocular pathology in multiple sclerosis: retinal atrophy and inflammation irrespective of disease duration

Autor: Ingrid V. Allen, Roy W. Lyness, Stephen L. Hauser, Ari J. Green, Stephen McQuaid

Publikováno v: Brain. 133:1591-1601

There has been growing interest in the use of retinal imaging for tracking disease progression in multiple sclerosis. However, systematic and detailed pathological descriptions of retinal tissue in multiple sclerosis are lacking. Graded, histological

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9193ceb844b3705bb9e5ffce89354d08
https://doi.org/10.1093/brain/awq080

Rational Attenuation of a Morbillivirus by Modulating the Activity of the RNA-Dependent RNA Polymerase

Autor: Thomas Barrett, Ashley C. Banyard, David D. Brown, Ingrid V. Allen, W. Paul Duprex, Bertus K. Rima, Michael D. Baron

Publikováno v: Journal of Virology. 79:14330-14338

Negative-strand RNA viruses encode a single RNA-dependent RNA polymerase (RdRp) which transcribes and replicates the genome. The open reading frame encoding the RdRp from a virulent wild-type strain of rinderpest virus (RPV) was inserted into an expr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff1e5a2075249c34d75629bedaee05d
https://doi.org/10.1128/jvi.79.22.14330-14338.2005

of the Eighty-Seventh Meeting of the British Neuropathological Society held at the Royal Free Hospital School of Medicine 15–17 December 1993

Autor: Ingrid V. Allen

Publikováno v: Neuropathology and Applied Neurobiology. 20:294-313

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cf529d18e37356834d8975dcb08ad97a
https://doi.org/10.1111/j.1365-2990.1994.tb00972.x