Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ingrid Uhlenbusch-Koerwer"'
Autor:
Christian Lupinek, Kurt Derfler, Silvia Lee, Thomas Prikoszovich, Oliver Movadat, Eva Wollmann, Carolin Cornelius, Milena Weber, Renate Fröschl, Regina Selb, Katharina Blatt, Dubravka Smiljkovic, Volker Schoder, René Cervenka, Thomas Plaichner, Gottfried Stegfellner, Hans Huber, Rainer Henning, Justyna Kozik-Jaromin, Thomas Perkmann, Verena Niederberger, Ventzislav Petkov, Peter Valent, Adelheid Gauly, Hans Peter Leinenbach, Ingrid Uhlenbusch-Koerwer, Rudolf Valenta
Publikováno v:
EBioMedicine, Vol 17, Iss C, Pp 119-133 (2017)
Background: Prevention of IgE-binding to cellular IgE-receptors by anti-IgE (Omalizumab) is clinically effective in allergic asthma, but limited by IgE threshold-levels. To overcome this limitation, we developed a single-use IgE immunoadsorber column
Externí odkaz:
https://doaj.org/article/fc182c7678904540a33c121811dc1d3f
Autor:
Thomas Plaichner, Kurt Derfler, Ingrid Uhlenbusch-Koerwer, Hans Huber, Silvia Lee, Eva Wollmann, Rudolf Valenta, Hans Peter Leinenbach, Rene Cervenka, Adelheid Gauly, Volker Schoder, Thomas Prikoszovich, Rainer Henning, Oliver Movadat, Justyna Kozik-Jaromin, Christian Lupinek, Gottfried Stegfellner, Ventzislav Petkov
Publikováno v:
5.3 Allergy and Immunology.
A novel highly selective single-use IgE-immunoadsorber, IgEnio, has been developed using BM10, a non-anaphylactic fragment of a monoclonal anti-human IgE antibody. In a proof of concept study, IgEnio was used to deplete IgE from the plasma of patient