Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ingrid Spaan"'
Publikováno v:
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-18 (2018)
Abstract Multiple myeloma is the second most frequent hematological malignancy in the western world and remains incurable, predominantly due to acquired drug resistance and disease relapse. The highly conserved Wnt signal transduction pathway, which
Externí odkaz:
https://doaj.org/article/54b27bb2a10b45318f428f2e08fc63e5
Publikováno v:
Cancers, Vol 13, Iss 18, p 4668 (2021)
Multiple myeloma (MM) is a hematological malignancy that is still considered incurable due to the development of therapy resistance and subsequent relapse of disease. MM plasma cells (PC) use NFκB signaling to stimulate cell growth and disease progr
Externí odkaz:
https://doaj.org/article/88b926d2065f4a62b3c1db5ca70a6c12
Autor:
Ingrid Spaan, Niels van Nieuwenhuijzen, Thomas Kimman, Dedeke Rockx-Brouwer, Ralph G. Tieland, Madelon M. Maurice, Monique C. Minnema, Reinier A. Raymakers, Victor Peperzak
Publikováno v:
Blood Advances. 7:1103-1107
Publikováno v:
Cancers
Volume 13
Issue 18
Cancers, Vol 13, Iss 4668, p 4668 (2021)
Volume 13
Issue 18
Cancers, Vol 13, Iss 4668, p 4668 (2021)
Simple Summary Multiple myeloma (MM) is a blood cancer that is still incurable because patients become insensitive to available treatments. The cancerous cells in MM misuse a signaling route, called the NFκB pathway, to make MM more difficult to tre
Autor:
Anne Slomp, Thomas Kimman, Niels van Nieuwenhuijzen, Laura M Moesbergen, Victor Peperzak, Ingrid Spaan, Laura M. Timmerman, Marta Cuenca, Reinier Raymakers, Monique C. Minnema
Publikováno v:
Blood Adv
Novel combination therapies have markedly improved the lifespan of patients with multiple myeloma (MM), but drug resistance and disease relapse remain major clinical problems. Dexamethasone and other glucocorticoids are a cornerstone of conventional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::617f2f0388a193821fc8c3c13a4b20d0
https://europepmc.org/articles/PMC8270664/
https://europepmc.org/articles/PMC8270664/
Autor:
Hai-Kun Liu, Ingrid Spaan, Peter Bugert, Peter Angel, Tanja Eisemann, Barbara Costa, Andrey Korshunov, Heike Peterziel, Jens Strelau
Publikováno v:
Blood Advances. 3:1092-1102
Binding of the sialomucin-like transmembrane glycoprotein podoplanin (PDPN) to the platelet receptor C-type lectin-like receptor 2 induces platelet activation and aggregation. In human high-grade gliomas, PDPN is highly expressed both in tumor cells
Autor:
Victor Peperzak, Anne Slomp, Monique C. Minnema, Ingrid Spaan, Reinier Raymakers, Marta Cuenca, Thoman Kimman, Laura M. Timmerman
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 19:e110
Publikováno v:
Journal of hematology & oncology, 11(1). BioMed Central
Journal of Hematology & Oncology
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-18 (2018)
Journal of Hematology & Oncology
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-18 (2018)
Multiple myeloma is the second most frequent hematological malignancy in the western world and remains incurable, predominantly due to acquired drug resistance and disease relapse. The highly conserved Wnt signal transduction pathway, which plays a k
Publikováno v:
Cancer Research, 78(10), 2449. American Association for Cancer Research Inc.
Multiple myeloma (MM) is a treatable, but incurable, malignancy of plasma cells (PC) in the bone marrow (BM). It represents the final stage in a continuum of PC dyscrasias and is consistently preceded by a premalignant phase termed monoclonal gammopa