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pro vyhledávání: '"Ingrid Ramm"'
Autor:
Ingrid Ramm, Adrian Sanchez-Fernandez, Jaeyeong Choi, Christian Lang, Jonas Fransson, Herje Schagerlöf, Marie Wahlgren, Lars Nilsson
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1853 (2021)
The addition of glycerol to protein solutions is often used to hinder the aggregation and denaturation of proteins. However, it is not a generalised practice against chemical degradation reactions. The chemical degradation of proteins, such as deamid
Externí odkaz:
https://doaj.org/article/9f1544ffd84b4b91b9480d507d08173d
Autor:
Ingrid Ramm, Mats Leeman, Herje Schagerlöf, Ileana Rodríguez León, Alejandra Castro, Lars Nilsson
Publikováno v:
Analytical and Bioanalytical Chemistry. 414:8191-8200
Physiochemical degradation of therapeutic proteins in vivo during plasma circulation after administration can have a detrimental effect on their efficacy and safety profile. During drug product development, in vivo animal studies are necessary to exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e4cbcc835b231d0e9a0f837fa64db3
https://doi.org/10.1007/s00216-022-04355-2
https://doi.org/10.1007/s00216-022-04355-2