Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ingrid N. Michon"'
Autor:
Menno Hoekstra, Miranda Stitzinger, Eva J.A. van Wanrooij, Ingrid N. Michon, J. Kar Kruijt, J. Kamphorst, M. Van Eck, E. Vreugdenhil, Theo J.C. Van Berkel, Johan Kuiper
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 10, Pp 2198-2207 (2006)
Liver parenchymal cells play a dominant role in hepatic metabolism and thereby total body cholesterol homeostasis. To gain insight into the specific pathways and genes involved in the response of liver parenchymal cells to increased dietary lipid lev
Externí odkaz:
https://doaj.org/article/fe0853491e054cafab517f3c6d5e6b87
Autor:
Gijs H.M. van Puijvelde, Theo J.C. Van Berkel, Eva J.A. van Wanrooij, Niels Peterse, Paula de Vos, Thomas van Es, Johan Kuiper, Ingrid N. Michon
Publikováno v:
Vaccine
Vaccine, 29(5), 976-983
Vaccine, 29(5), 976-983
Background Interleukin 15 (IL-15) is a pro-inflammatory cytokine involved in inflammatory diseases and IL-15 is expressed in atherosclerotic plaques. Methods To establish the role of IL-15 in atherosclerosis we studied the effect of IL-15 on atherosc
Autor:
Tom J.M. Molenaar, Johan Kuiper, Erik A.L. Biessen, Ingrid N. Michon, Arnaud D. Hauer, Jan H. von der Thüsen, Theo J.C. Van Berkel
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1591(1-3):87-97
Restenosis after angioplasty occurs in 30–40% of the treated patients. To develop a strategy to deliver drugs to restenotic lesions, we selected phages that bind to proliferating vascular smooth muscle cells (VSMC), from a random constraint 15-mer
Autor:
Theo J.C. Van Berkel, Johan Kuiper, Sonja A.M. de Haas, Erik A.L. Biessen, Tom J.M. Molenaar, Ingrid N. Michon
Publikováno v:
Virology. 293:182-191
Internalization and degradation of filamentous bacteriophage M13 by a specific target cell may have major consequences for the recovery of phage in in vivo biopanning of phage libraries. Therefore, we investigated the pharmacokinetics and processing
Autor:
Hans E. Junginger, Tom J.M. Molenaar, Gerrit Borchard, Bogdan I. Florea, T. J. C. Van Berkel, Ingrid N. Michon, Ilze Bot, E.A.L. Biessen, Johan Kuiper
Publikováno v:
Journal of drug targeting. 11(7)
Differentiated, human submucosal-gland carcinoma, Calu-3 cell monolayers were used as in vitro model for the airway epithelium. Internalised phage were selected from a recombinant pComb8 phage library by repetitive cycles of bio-panning on Calu-3 mon
Autor:
Marc Hoylaerts, Ingrid N. Michon, Theo J.C. Van Berkel, Hans Pannekoek, Arnaud Bonnefoy, Sonja A.M. de Haas, Tom J.M. Molenaar, Erik A.L. Biessen, Johan Kuiper, Chantal C. M. Appeldoorn
Publikováno v:
Blood, 100(10), 3570-3577. American Society of Hematology
P-selectin is a leukocyte adhesion receptor expressed on activated vascular endothelium and platelets that mediates leukocyte rolling and attachment. Because P-selectin is critically involved in inflammation, we used phage display libraries to identi
Autor:
Louis C. Penning, Ingrid N. Michon, Johan Kuiper, Tom J.M. Molenaar, Erik A.L. Biessen, Theo J.C. Van Berkel
Publikováno v:
Biochemical and biophysical research communications. 293(4)
TGF-beta1 is a potent regulator of vascular smooth muscle cell (VSMC) proliferation, migration, and extracellular matrix (ECM) synthesis. In this study, we selected two peptides, IM-1 and IM-2, that bind to the TGF-beta type II receptor (TGF-beta RII