Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ingrid M. Knarston"'
Autor:
Gorjana Robevska, Anne Jørgensen, Andrew H. Sinclair, Elizabeth Georges, Svenja Pachernegg, Irene M. Ghobrial, Ingrid M. Knarston, Katie L. Ayers, Minoru Takasato, Alexander N. Combes, Pei Xuan Er, Melissa H. Little
Publikováno v:
Stem Cell Reports
Summary Currently an in vitro model that fully recapitulates the human embryonic gonad is lacking. Here we describe a fully defined feeder-free protocol to generate early testis-like cells with the ability to be cultured as an organoid, from human in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cededc7d28219334483a04d4367c525
https://doi.org/10.1016/j.stemcr.2020.10.009
https://doi.org/10.1016/j.stemcr.2020.10.009
Autor:
Vincent R. Harley, Peter Koopman, John M. Hutson, Vincent Corbin, Josephine Bowles, Rajini Sreenivasan, Andrew H. Sinclair, Alexander E. Quinn, Katie L. Ayers, Jacqueline K. Hewitt, Jacqueline Tan, Jocelyn van den Bergen, Brittany Croft, Dung Chi Vu, Thomas Ohnesorg, Emanuele Pelosi, Ingrid M. Knarston, Gorjana Robevska
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature Communications
Nature Communications
Disorders of sex development (DSDs) are conditions affecting development of the gonads or genitalia. Variants in two key genes, SRY and its target SOX9, are an established cause of 46,XY DSD, but the genetic basis of many DSDs remains unknown. SRY-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76aead15948024cbd027bae379b86e17
http://link.springer.com/article/10.1038/s41467-018-07784-9
http://link.springer.com/article/10.1038/s41467-018-07784-9
Autor:
Matthew Parry, Aniruddha Chatterjee, Erin C. Macaulay, Antonio Ahn, Jackie L. Ludgate, Ian M. Morison, Peter A. Stockwell, Michael R. Eccles, Tim Foster, Robert J. Weeks, Ingrid M. Knarston
Publikováno v:
Epigenomics. 9:823-832
Aim: Validation of sequencing-based DNA methylation data is an important step for meaningful translation of findings. However, there has been limited assessment of different platforms to validate methylation data from next generation sequencing. Meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf2f09d6145425c14a1dea156a92d07
https://doi.org/10.2217/epi-2016-0176
https://doi.org/10.2217/epi-2016-0176
Autor:
Ingrid M. Knarston, Marion Beaumont, Célia Ravel, Linda Akloul, Sylvie Jaillard, Christèle Dubourg, Elena J. Tucker, Marc-Antoine Belaud-Rotureau, Andrew H. Sinclair, Katie L. Ayers, Jocelyn van den Bergen, Sylvie Odent, Gorjana Robevska, Céline Pimentel, Guilhem Jouve, Rajini Sreenivasan, Solène Duros, Sonia Grover, Brittany Croft
Publikováno v:
Maturitas
Maturitas, Elsevier, 2020, 131, pp.78-86. ⟨10.1016/j.maturitas.2019.10.011⟩
Maturitas, 2020, 131, pp.78-86. ⟨10.1016/j.maturitas.2019.10.011⟩
Maturitas, Elsevier, 2020, 131, pp.78-86. ⟨10.1016/j.maturitas.2019.10.011⟩
Maturitas, 2020, 131, pp.78-86. ⟨10.1016/j.maturitas.2019.10.011⟩
International audience; Ovarian deficiency, including diminished ovarian reserve and premature ovarian insufficiency, represents one of the main causes of female infertility. Little is known of the genetic basis of diminished ovarian reserve, while p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a787bc9b08389c0aed61802c039f0bc
https://pubmed.ncbi.nlm.nih.gov/31787151
https://pubmed.ncbi.nlm.nih.gov/31787151
Autor:
Peter Koopman, Josephine Bowles, Dung Chi Vu, Thomas Ohnesorg, Vincent R. Harley, Katie L. Ayers, Emanuele Pelosi, Alexander E. Quinn, Vincent Corbin, Jacqueline Tan, Jocelyn van den Bergen, Rajini Sreenivasan, Andrew H. Sinclair, Brittany Croft, Gorjana Robevska, John M. Hutson, Jacqueline K. Hewitt, Ingrid M. Knarston
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
Nature Communications
Nature Communications
Disorders of sex development (DSDs) are conditions affecting development of the gonads or genitalia. Variants in two key genes, SRY and its target SOX9, are an established cause of 46,XY DSD, but the genetic basis of many DSDs remains unknown. SRY-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531d377337d2d7cd08d848100381117f
https://doaj.org/article/e37751dddf224b2686fa5dc43ff347dd
https://doaj.org/article/e37751dddf224b2686fa5dc43ff347dd
Autor:
Ingrid M. Knarston, Gorjana Robevska, Jocelyn A van den Bergen, Stefanie Eggers, Brittany Croft, Jason Yates, Remko Hersmus, Leendert H. J. Looijenga, Fergus J. Cameron, Klaus Monhike, Katie L. Ayers, Andrew H. Sinclair
Publikováno v:
Human Mutation. 40:i-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9834783557b5e45c1861038599728f95
https://doi.org/10.1002/humu.22672
https://doi.org/10.1002/humu.22672
Publikováno v:
Clinical science (London, England : 1979). 130(6)
In the female gonad, distinct signalling pathways activate ovarian differentiation while repressing the formation of testes. Human disorders of sex development (DSDs), such as 46,XX DSDs, can arise when this signalling is aberrant. Here we review the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b4fbfa934456b8fe0338d6a68c6252
https://pubmed.ncbi.nlm.nih.gov/26846580
https://pubmed.ncbi.nlm.nih.gov/26846580