Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Ingrid M. C. Kamerling"'
Autor:
Manon L. M. Prins, Geert V. T. Roozen, Cilia. R. Pothast, Wesley Huisman, Rob van Binnendijk, Gerco den Hartog, Vincent P. Kuiper, Corine Prins, Jacqueline J. Janse, Olivia. A. C. Lamers, Jan Pieter R. Koopman, Annelieke C. Kruithof, Ingrid M. C. Kamerling, Romy C. Dijkland, Alicia. C. de Kroon, Shohreh Azimi, Mariet C. W. Feltkamp, Marjan Kuijer, Simon P. Jochems, Mirjam H. M. Heemskerk, Frits R. Rosendaal, Meta Roestenberg, Leo G. Visser, Anna H. E. Roukens
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-10 (2024)
Abstract Fractional dosing can be a cost-effective vaccination strategy to accelerate individual and herd immunity in a pandemic. We assessed the immunogenicity and safety of primary intradermal (ID) vaccination, with a 1/5th dose compared with the s
Externí odkaz:
https://doaj.org/article/8c7cdcae1f5e4775b3bf74058e2d2a84
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 6, Pp 2391-2398 (2021)
Abstract Clinical development of vaccines in a pandemic situation should be rigorous but expedited to tackle the pandemic threat as fast as possible. We explored the effects of a novel vaccine trial strategy that actively identifies and enrolls subje
Externí odkaz:
https://doaj.org/article/0128ea5da08a4835b3f51007fda9720f
Autor:
Josephina P. M. Vrouwe, Ingrid M. C. Kamerling, Michiel J. vanEsdonk, Josbert M. Metselaar, Frederik E. Stuurman, Gabri van derPluijm, Jacobus Burggraaf, Susanne Osanto
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 5, Pp n/a-n/a (2021)
Abstract Dexamethasone has antitumor activity in metastatic castration resistant prostate cancer (mCRPC). We aimed to investigate intravenous liposome‐encapsulated dexamethasone disodium phosphate (liposomal dexamethasone) administration in mCRPC p
Externí odkaz:
https://doaj.org/article/7f6f12eb65c74ad0b8cee9f1481033da
Autor:
Cécile L. Berends, Lisa Pagan, Michiel J. vanEsdonk, Naomi B. Klarenbeek, Kirsten R. Bergmann, Matthijs Moerland, Vincent van derWel, Saco J. deVisser, Hans Büller, Frans deLoos, Wouter S. deVries, Hans Waals, Leo G. J. deLeede, Jacobus Burggraaf, Ingrid M. C. Kamerling
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 2, Pp n/a-n/a (2021)
Abstract The strict intake regimen of cysteamine bitartrate formulations, associated with side effects, is a concern for the treatment compliance in cystinosis therapy. Therefore, there is a need for a cysteamine formulation with an improved pharmaco
Externí odkaz:
https://doaj.org/article/7edf448348d44fbf8dec9db02864388c
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Externí odkaz:
https://doaj.org/article/72bdd58982c5499a9e83161cdad1ae3f
Publikováno v:
Frontiers in Medicine, Vol 5 (2018)
Vaccines can be extremely cost-effective public health measures. Unfortunately the research and development (R&D) of novel vaccines is suffering from rising costs and declining success rates. Because many vaccines target low- and middle income market
Externí odkaz:
https://doaj.org/article/74f048469238432dad58f48d5cea5ecc
Autor:
Anneke C. Dijkmans, Dinemarie M. Kweekel, Jaap T. van Dissel, Michiel J. van Esdonk, Ingrid M. C. Kamerling, Jacobus Burggraaf
Publikováno v:
Antibiotics, Vol 8, Iss 3, p 119 (2019)
Severe streptococcal infections are commonly treated with intravenous followed by oral penicillin (pheneticillin) therapy. However, switching from iv to oral therapy is complicated by the variability in oral pheneticillin absorption. We employed an O
Externí odkaz:
https://doaj.org/article/95c2d5b165d74422a1696ba2b85361e4
Autor:
Manon L. M. Prins, Johan L. van der Plas, Maurits F. J. M. Vissers, Cécile L. Berends, Gaby Tresch, Marianne Soergel, Elena Fernández, Nikita van den Berge, Daniël Duijsings, Christof Zitt, Vaia Stavropoulou, Maya Zimmermann, Roxana F. Drake, Jacobus Burggraaf, Geert H. Groeneveld, Ingrid M. C. Kamerling
Publikováno v:
British Journal of Clinical Pharmacology. 89:1105-1114
To assess viral clearance, pharmacokinetics, tolerability and symptom evolution following ensovibep administration in symptomatic COVID-19 outpatients.In this open-label, first-in-patient study a single dose of either 225 mg (n = 6) or 600 mg (n = 6)
Autor:
Aliede E. in ‘t Veld, Hendrika W. Grievink, Johan L. van der Plas, Boukje C. Eveleens Maarse, Sebastiaan J. W. van Kraaij, Tess D. Woutman, Mascha Schoonakker, Naomi B. Klarenbeek, Marieke L. de Kam, Ingrid M. C. Kamerling, Manon A. A. Jansen, Matthijs Moerland
Publikováno v:
Immunologic Research.
Based on its wide range of immunosuppressive properties, hydroxychloroquine (HCQ) is used for the treatment of several autoimmune diseases. Limited literature is available on the relationship between HCQ concentration and its immunosuppressive effect
Autor:
Geert Jan Groeneveld, Erica S. Klaassen, Ingrid M C Kamerling, Emilie M. J. van Brummelen, Vanessa Ville, Annie-Claude Benichou, Cécile L. Berends, Kirsten R. Bergmann, Laurence M Moss, Victor Juarez-Perez
Publikováno v:
British Journal of Clinical Pharmacology, 88(1), 103-114. WILEY
Aim Dual enkephalinase inhibitors (DENKIs) are involved in the regulation of nociception via opioid receptors. The novel compound STR-324 belongs to the DENKI pharmacological class. This first-in-human study evaluated the safety, tolerability, pharma