Výsledky vyhledávání - "Ingrid M E Desar"

Akademický článek

Facilitators and barriers to conducting an efficient, competent and high-quality oncological multidisciplinary team meeting

Autor: Gijs Hesselink, Ingrid M E Desar, Valery E P P Lemmens, Janneke E W Walraven, Rob H A Verhoeven, Renske van der Meulen, Jacobus J M van der Hoeven

Publikováno v: BMJ Open Quality, Vol 12, Iss 1 (2023)

Background Optimal oncological care nowadays requires discussing every patient in a multidisciplinary team meeting (MDTM). The number of patients to be discussed is rising rapidly due to the increasing incidence and prevalence of cancer and the emerg

Externí odkaz: https://doaj.org/article/6b16325acbc4489e972281468bea7f18

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Akademický článek

The route to diagnosis of sarcoma patients: Results from an interview study in the Netherlands and the United Kingdom.

Autor: Vicky L M N Soomers, Winette T A van der Graaf, Shane Zaidi, Suzanne E J Kaal, Andrew J Hayes, Bart H W B Schreuder, Robin L Jones, Ingrid M E Desar, Olga Husson

Publikováno v: PLoS ONE, Vol 15, Iss 12, p e0243439 (2020)

IntroductionSarcomas are rare tumours. Early diagnosis is challenging, but important for local control and potentially survival and quality of life(QoL). We investigated (1)the route to diagnosis (RtD) experienced by sarcoma patients, including facto

Externí odkaz: https://doaj.org/article/287f717f1365431cbb9a27685ac9a531

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Akademický článek

Levels of circulating tumor DNA correlate with tumor volume in gastro‐intestinal stromal tumors: an exploratory long‐term follow‐up study

Autor: Roos F. Bleckman, Charlotte M. S. C. Haag, Naomi Rifaela, Gerrieke Beukema, Ron H. J. Mathijssen, Neeltje Steeghs, Hans Gelderblom, Ingrid M. E. Desar, Arjen Cleven, Arja terElst, Ed Schuuring, Anna K. L. Reyners

Publikováno v: Molecular Oncology, Vol 18, Iss 11, Pp 2658-2667 (2024)

Patients with gastro‐intestinal stromal tumors (GISTs) undergoing tyrosine kinase inhibitor therapy are monitored with regular computed tomography (CT) scans, exposing patients to cumulative radiation. This exploratory study aimed to evaluate circu

Externí odkaz: https://doaj.org/article/24846d9179084dad86b3bdbabda1dee8

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Akademický článek

Therapeutic drug monitoring to personalize dosing of imatinib, sunitinib, and pazopanib: A mixed methods study on barriers and facilitators

Autor: Kim Westerdijk, Neeltje Steeghs, Casper S. J. Tacke, Winette T. A. van derGraaf, Nielka P. vanErp, Gerard vanOortmerssen, Rosella P. M. G. Hermens, Ingrid M. E. Desar, In collaboration with the Dutch Pharmacology Oncology Group (DPOG)

Publikováno v: Cancer Medicine, Vol 12, Iss 22, Pp 21041-21056 (2023)

Abstract Background Personalized dosing based on measurement of individual drug levels and adjusting the dose accordingly can improve efficacy and decrease unnecessary toxicity of oncological treatment. For imatinib, sunitinib, and pazopanib, this th

Externí odkaz: https://doaj.org/article/f526d700fa4545ab81c035bd276d9978

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Akademický článek

Exposure–response analyses of cabozantinib in patients with metastatic renal cell cancer

Autor: Stefanie D. Krens, Nielka P. van Erp, Stefanie L. Groenland, Dirk Jan A. R. Moes, Sasja F. Mulder, Ingrid M. E. Desar, Tom van der Hulle, Neeltje Steeghs, Carla M. L. van Herpen

Publikováno v: BMC Cancer, Vol 22, Iss 1, Pp 1-12 (2022)

Abstract Aim In the registration trial, cabozantinib exposure ≥ 750 ng/mL correlated to improved tumor size reduction, response rate and progression free survival (PFS) in patients with metastatic renal cell cancer (mRCC). Because patients in routi

Externí odkaz: https://doaj.org/article/f27b5243be1f49888ffdb384331fa067

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Akademický článek

Targeting the FAK-Src Complex in Desmoplastic Small Round Cell Tumors, Ewing Sarcoma, and Rhabdomyosarcoma

Autor: Anke E. M. van Erp, Melissa H. S. Hillebrandt-Roeffen, Niek F. H. N. van Bree, Tim A. Plüm, Uta. E. Flucke, Ingrid M. E. Desar, Emmy D. G. Fleuren, Winette T. A. van der Graaf, Yvonne M. H. Versleijen-Jonkers

Publikováno v: Sarcoma, Vol 2022 (2022)

Desmoplastic small round cell tumors (DSRCTs), Ewing sarcoma (ES), and alveolar and embryonal rhabdomyosarcoma (ARMS and ERMS) are malignant sarcomas typically occurring at young age, with a poor prognosis in the metastatic setting. New treatment opt

Externí odkaz: https://doaj.org/article/54526dee4e644555857ded7c69c21881

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Improved Efficacy of First-Line Imatinib in Advanced Gastrointestinal Stromal Tumors (GIST)

Autor: Mahmoud Mohammadi, Nikki S. IJzerman, Dide den Hollander, Roos F. Bleckman, Astrid W. Oosten, Ingrid M. E. Desar, An K. L. Reyners, Neeltje Steeghs, Hans Gelderblom

Publikováno v: Targeted Oncology, 18, 415-423
Targeted oncology. SPRINGER
Targeted Oncology, 18, 3, pp. 415-423
Targeted Oncology, 18(3), 415-423. Springer Paris

Contains fulltext : 292913.pdf (Publisher’s version ) (Open Access) BACKGROUND: Patients with unresectable and metastasized gastrointestinal stromal tumor (GIST) experienced a remarkable improvement of progression-free survival (PFS) and overall su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef08572345892cbae2e4faab5be56cf
https://doi.org/10.1007/s11523-023-00960-y

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The influence of multidisciplinary team meetings on treatment decisions in advanced bladder cancer

Autor: Janneke E W, Walraven, Theodora M, Ripping, Jorg R, Oddens, Bas W G, van Rhijn, Catharina A, Goossens-Laan, Maarten C C M, Hulshof, Lambertus A, Kiemeney, J A, Witjes, Valery E P P, Lemmens, Jacobus J M, van der Hoeven, Ingrid M E, Desar, Katja K H, Aben, Lisa M C, van Hoogstraten

Publikováno v: BJU International, 131, 2, pp. 244-252
BlaZIB Study Group 2022, ' The influence of multidisciplinary team meetings on treatment decisions in advanced bladder cancer ', BJU International . https://doi.org/10.1111/bju.15856
BJU International, 131, 244-252
BJU International. Wiley-Blackwell
BJU international. Wiley-Blackwell

Contains fulltext : 291201.pdf (Publisher’s version ) (Open Access) OBJECTIVES: To investigate the role of specialised genitourinary multidisciplinary team meetings (MDTMs) in decision-making and identify factors that influence the probability of r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df50753121284beff9135fbe0ba2cb8
https://hdl.handle.net/2066/291201

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Dutch Gastrointestinal Stromal Tumor (GIST) Registry Data Comparing Sunitinib with Imatinib Dose Escalation in Second-Line Advanced Non-KIT Exon 9 Mutated GIST Patients

Autor: Mahmoud Mohammadi, Thekla M. Jansen-Werkhoven, Nikki S. Ijzerman, Dide den Hollander, Roos F. Bleckman, Astrid W. Oosten, Ingrid M. E. Desar, An K. L. Reyners, Neeltje Steeghs, Hans Gelderblom

Publikováno v: Targeted Oncology, 17, 6, pp. 627-634
Targeted oncology, 17(6), 627-634. SPRINGER
Targeted Oncology, 17, 627-634
Targeted Oncology, 17(6), 627-634. Springer Paris
Targeted Oncology, 17(6), 627-634. SPRINGER

Contains fulltext : 287667.pdf (Publisher’s version ) (Open Access) BACKGROUND: The prognosis of patients with advanced gastrointestinal stromal tumor (GIST) has improved greatly after the introduction of imatinib. However, primary or secondary res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49f27e3b1a5d8e44c14233b78c5e829
https://doi.org/10.1007/s11523-022-00926-6

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