Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Ingrid M, Garrelds"'
Autor:
André F. Rodrigues, Oliver Domenig, Ingrid M. Garrelds, A.H. Jan Danser, Natalia Alenina, Marko Poglitsch, Michael Bader
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 22 (2024)
Externí odkaz:
https://doaj.org/article/4b3a0ea4b1d54dcd91efb2a1e887aee0
Autor:
Simone de Vries Lentsch, Ingrid M. Garrelds, A. H. Jan Danser, Gisela M. Terwindt, Antoinette MaassenVanDenBrink
Publikováno v:
The Journal of Headache and Pain, Vol 23, Iss 1, Pp 1-7 (2022)
Highlights • Lower serum levels of calcitonin gene-related peptide (CGRP)-like immunoreactivity (CGRP-LI) in migraine patients at 2–4 weeks after starting treatment with erenumab were associated with better treatment response after three months.
Externí odkaz:
https://doaj.org/article/15c3412aee78415fbcc3b52d8208e02a
Autor:
Eduardo Rivera-Mancilla, Linda Al-Hassany, Heleen Marynissen, Dorien Bamps, Ingrid M. Garrelds, Jérôme Cornette, A. H. Jan Danser, Carlos M. Villalón, Jan N. de Hoon, Antoinette MaassenVanDenBrink
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 156 (2024)
Transient receptor potential (TRP) channels are pivotal in modulating vascular functions. In fact, topical application of cinnamaldehyde or capsaicin (TRPA1 and TRPV1 channel agonists, respectively) induces “local” changes in blood flow by releas
Externí odkaz:
https://doaj.org/article/6da861e0a7624ecc9eac267bb8c3cd87
Autor:
Estrellita Uijl, Dien Ye, Liwei Ren, Katrina M. Mirabito Colafella, Richard van Veghel, Ingrid M. Garrelds, Hong S. Lu, Alan Daugherty, Ewout J. Hoorn, Paul Nioi, Don Foster, A. H. Jan Danser
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 15 (2022)
Background A single dose of small interfering RNA (siRNA) targeting liver angiotensinogen eliminates hepatic angiotensinogen and lowers blood pressure. Angiotensinogen elimination raises concerns for clinical application because an angiotensin rise i
Externí odkaz:
https://doaj.org/article/1186619f806d410bac10cb41b2836b72
Autor:
Keivan Golshiri, Ehsan Ataei Ataabadi, Annika A. Jüttner, Gretchen L. Snyder, Robert E Davis, Amy Lin, Lei Zhang, René de Vries, Ingrid M Garrelds, Frank P. J. Leijten, A. H. Jan Danser, Anton J. M. Roks
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Age-related cardiovascular diseases (CVDs) remain among the leading global causes of death, and vascular smooth muscle cell (VSMC) remodeling plays an essential role in its pathology. Reduced NO-cGMP pathway signaling is a major feature and pathogeni
Externí odkaz:
https://doaj.org/article/432cd51823f34d07a3f3d4c35f7842bb
Autor:
Leni van Doorn, Wesley J. Visser, Daan C. H. van Dorst, Katrina M. Mirabito Colafella, Stijn L. W. Koolen, Anneke van Egmond- de Mik, Ingrid M. Garrelds, Dominique M. Bovée, Esther Oomen- de Hoop, Sander Bins, Ferry A. L. M. Eskens, Ewout J. Hoorn, A. H. Jan Danser, Ron H. J. Mathijssen, Jorie Versmissen
Publikováno v:
British Journal of Cancer, 128(2), 354-362. Nature Publishing Group
Background: Vascular endothelial growth factor inhibitors (VEGFIs) are effective anticancer agents which often induce hypertension. VEGFI-induced hypertension is sodium-sensitive in animal studies. Therefore, the efficacy of dietary sodium restrictio
Autor:
Katrina M. Mirabito Colafella, Daan C.H. van Dorst, Rugina I. Neuman, Leni van Doorn, Karla Bianca Neves, Augusto C. Montezano, Ingrid M. Garrelds, Richard van Veghel, René de Vries, Estrellita Uijl, Marian C. Clahsen-van Groningen, Hans J. Baelde, Anton H. van den Meiracker, Rhian M. Touyz, Willy Visser, A.H. Jan Danser, Jorie Versmissen
Publikováno v:
Clinical Science, 136(9), 675-694. Portland Press, Ltd.
Vascular endothelial growth factor antagonism with angiogenesis inhibitors in cancer patients induces a ‘preeclampsia-like’ syndrome including hypertension, proteinuria and elevated endothelin (ET)-1. Cyclo-oxygenase (COX) inhibition with aspirin
Autor:
Edwyn O. Cruz‐López, Liwei Ren, Estrellita Uijl, Marian C. Clahsen‐van Groningen, Richard van Veghel, Ingrid M. Garrelds, Oliver Domenig, Marko Poglitsch, Ivan Zlatev, Timothy Rooney, Anne Kasper, Paul Nioi, Don Foster, A. H. Jan Danser
Publikováno v:
British Journal of Pharmacology, 180(1), 80-93. Wiley-Blackwell
Background and Purpose Small interfering RNA (siRNA) targeting liver angiotensinogen lowers blood pressure, but its effects in hypertensive diabetes are unknown. Experimental Approach To address this, TGR (mRen2)27 rats (angiotensin II-dependent hype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be6a4fef44c7e318eeb2093a55188ebd
https://pure.eur.nl/en/publications/d406679c-44b9-43f0-b71e-b517c7e3b63a
https://pure.eur.nl/en/publications/d406679c-44b9-43f0-b71e-b517c7e3b63a
Autor:
Eva L. van der Linden, Adrienne Halley, Karlijn A. C. Meeks, Felix Chilunga, Charles Hayfron-Benjamin, Andrea Venema, Ingrid M. Garrelds, A. H. Jan Danser, Bert-Jan van den Born, Peter Henneman, Charles Agyemang
Publikováno v:
Clinical Epigenetics, 14(1):159. BioMed Central Ltd.
Clinical epigenetics, 14(1):159. Springer Verlag
Clinical epigenetics, 14(1):159. Springer Verlag
Background The epigenetic regulation of the renin–angiotensin–aldosterone system (RAAS) potentially plays a role in the pathophysiology underlying the high burden of hypertension in sub-Saharan Africans (SSA). Here we report the first epigenome-w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119ce59dfaae758e019bbff53cb08b10
https://pure.eur.nl/en/publications/1fe6f91e-03b6-4473-aa67-f4b2dbbb564d
https://pure.eur.nl/en/publications/1fe6f91e-03b6-4473-aa67-f4b2dbbb564d
Autor:
Edwyn Omar Cruz Lopez, Liwei Ren, Estrellita Uijl, Marian C. Clahsen-Van Groningen, Richard Van Veghel, Ingrid M. Garrelds, Oliver Domenig, Marko Poglitsch, Ivan Zlatev, Timothy Rooney, Anne Kasper, Paul Nioi, Don Foster, A.H. Jan Danser
Publikováno v:
Journal of Hypertension, 40(suppl. 1):e193. Lippincott Williams & Wilkins
OBJECTIVE: Small interfering RNA (siRNA) targeting liver angiotensinogen (AGT) exerts beneficial effects on blood pressure and kidney function, but its effects in diabetes are still unknown. DESIGN AND METHOD: To address this, TGR(mREN2)27 rats (a mo